ANNEX PUBLISHERS

Journal of Immunology and Infectious Diseases

Editorial Board Member - JIID

Lan Zhou

Assistant Professor
Department of Pathology
Case Western Reserve University
United States
BIOGRAPHY:

Dr. Zhou completed her PhD thesis studying the gap junction protein regulation by Src oncogene. From 1999 to 2001, Dr. Zhou worked as a Research Associate at HHMI under Dr. John Lowe’s supervision to study how fucosyl- glycans modify selectin ligand activity in myeloid cell homeostasis. Since being recruited to Case Western Reserve University, Dr. Zhou has conducted research to try to understand the functional regulation of hematopoietic stem cell (HSC) fate specification and differentiation, myeloid and lymphoid cell homeostasis, and HSC self-renewal and niche development by fucosylated glycans present on Notch and selectin ligands. Dr. Zhou has also been interested in the role of Notch signaling in pancreatic cancer and aberrant glycosylation in colon carcinogenesis and tumor surveillance. Her long term research goals include

 1) to understand the mechanism(s) of which Notch as a signaling molecule and an adhesion molecule in HSC niche retention and quiescence maintenance

 2) to identify cellular and/or soluble factors that are critical for suppression of hematopoiesisby leukemia cells that are amenable to disruption

 3) to develop a deeper understanding of the role of Notch signaling in pancreatic cancer progression

 4) to use mouse models to investigate the mechanisms of aberrant glycosylation induced colitis and colon cancer development.



RESEARCH INTERESTS:

Dr. Zhou long term research focus is to understand the normal hematopoietic stem cell (HSC) niche regulation by Notch and associated adhesion processes, how leukemia regulates marrow micro-environment, and the role of aberrant Notch signaling in pancreatic cancer and colon cancer carcinogenesis and immuno-surveillance.





Other Editorial Board Members - JIID

Martin Michaelis

Professor of Molecular Medicine
Centre for Molecular Processing and School of Biosciences
University of Kent
United Kingdom

Guoshun Wang

Associate Professor
Department of Microbiology, Immunology and Parasitology
LSU Health New Orleans
United States

STEFAN KOSTADINOV

Assistant Professor
Alpert Medical School
Brown University
United States

David L. Hirschberg

Assistant Professor
Columbia University
United States

Bin Zhou

Scientist
J. Craig Venter Institute
United States

Henrique Serezani

Assistant Professor
Department of Microbiology and Immunology
Indiana University
United States

Jeffrey E. Lee

Assistant Professor
Laboratory Medicine & Pathobiology
University of Toronto
Canada

Jana Barlic-Dicen

Assistant Professor
Department of Cell Biology
University of Oklahoma Health Sciences Center
United States

Paul H. Wooley

Professor
Orthopaedic Research Institute
Wichita State University
United States

Matthias Clauss

Associate Professor
Department of Medicine
Indiana University
United States
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