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Articles Related to ALT

Modified and Combined Lateral and Posterolateral Approach an Alternative Treatment to Tibial Plateau Fractures

The selection of a surgical approach for the treatment of tibia plateau fractures is an important decision. Approximately 7% of all tibia plateau fractures affect the posterolateral corner. Displaced posterolateral tibia plateau fractures require anatomic articular reduction and buttress plate fixation on the posterior aspect. These aims are difficult to reach through a lateral or anterolateral approach. The standard posterolateral approach with fibula osteotomy and release of the posterolateral corner is a traumatic procedure, which includes the risk of fragment denudation. Isolated posterior approaches do not allow sufficient visual control of fracture reduction, especially if the fracture is complex. Therefore, the aim of this case report was to present a surgical approach for posterolateral tibial plateau fractures that both protects the soft tissue and allows for good visual control of fracture reduction. The approach involves a lateral arthrotomy for visualizing the joint surface and a posterolateral approach for the fracture reduction and plate fixation, which are both achieved through one posterolateral skin incision. Using this approach, we achieved reduction of the articular surface and stable fixation in patients at the final follow-up visit. No complications and no loss of reduction were observed. Additionally, the new posterolateral approach permits direct visual exposure and facilitates the application of a buttress plate. This approach does not require fibular osteotomy, and fragments of the posterolateral corner do not have to be detached from the soft tissue network.
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Access to and Utilisation of Adolescent Sexual and Reproductive Health Services among Secondary School Students in Mityana district, Uganda

The study of the access to and utilisation of Adolescent Sexual and Reproductive Health (ASRH) services among secondary school adolescents in, Mityana district was carried out in various schools in Ssekanyonyi sub-county. The study aimed to determine the prevalence of the ASRH burden, assess the utilisation of ASRH services in these schools and identify drivers/barriers to the utilisation of ASRH services among adolescents in secondary schools in Mityana district.
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Association between Physical Activity and Body Weight: Health Creation and Disease Prevention

Leisure time physical activity has a broad spectrum of health benefits. The objective of this study was to provide evidence and to support the association between physical activity and body weight. We used data from a probability sample of 8,128 individuals residing in Montreal (Canada). Multinomial multivariate logistic regression was used to determine the association between physical activity and body weight. Results showed no statistical association between physical activity and underweight. However, physical activity was associated with overweight, namely individuals doing less physical activity were significantly more likely to be overweight (OR=1.42; 95%CI=1.18- 1.69) than those performing intense physical activity. Additionally, the association between physical activity and obesity showed a negative incremental relationship, i.e. individuals reporting moderate physical activity were 29% more likely to be obese (OR=1.29; 95%CI=1.07- 1.55), and those reporting low physical activity were 123% more likely to be obese (OR=2.23; 95%CI=1.80-2.76) compared to intense physical activity status. Leisure time physical activity and overweight/obesity were significantly associated after accounting for several socioeconomic, lifestyle and health-related correlates. Due to the broader positive impact of physical activity on the health status of the individual, we advise health authorities to facilitate the propagation of healthy lifestyle in the community by adopting a health-creation policy in addition to the conventional disease-prevention strategy
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Bioequivalence between two Prolonged Release Tablets of Desvenlafaxine Succinate in Healthy Subjects under Fasting and Fed Conditions

Bioavailability in different formulations of desvenlafaxine100 mg prolonged-release tablets was compared in two bioequivalence studies, one under fasting conditions and the other after a standard breakfast. Both studies were a single dose, randomized, open-label, two-period crossover, with Brazilian male and female healthy subjects. Blood samples were taken during 48 h and plasmatic concentrations were determined using a validated UPLC-MS/MS method.
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Knowledge of HIV/AIDS Among General Practitioners in Health Facilities in Brazzaville in Republic of Congo

Despite the growing HIV burden, the disease continues to receive a relatively high public health priority in the Republic of Congo. To establish the knowledge, attitude, and practice on HIV/AIDS among general practitioners working in Brazzaville and to register their actual behavior in the prevention of HIV/AIDS. The study was a descriptive cross-sectional study. The sample size was 35 General Practitioners. A self- administered questionnaire was used to collect data in a four-week period in August 2017. Selected at random, were asked to participate. The data collected was analyzed using the Statistical Program for EpiInfo.
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Occupational Exposure to Blood and Bodily Fluids among Health Care Workers in a Medical Teaching Hospital

The objective of this study was to evaluate blood and bodily fluids exposure through needlestick injuries (NSI) and non-percutaneous incidents among healthcare workers (HCWs). This project utilized a dataset collected from J. W. Ruby Memorial Hospital in Morgantown, West Virginia, between January 1, 2014 and August 15, 2017. Data included de-identified codes of employees, occupations, types of exposure to bloodborne pathogens, routes of exposure, infectious disease exposures, and time incidents.
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Non-Operative Management of Acute Appendicitis – Evidence versus Practice in Eastern Health, Victoria, Australia

There has been an increasing body of literature on conservative management of acute appendicitis recently. The aim of this study was to evaluate the current practice of non-operative management of acute appendicitis in Eastern Health, a Melbourne metropolitan health network.
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Health-Related Quality of life of Complete versus Infarct artery-only Percutaneous Coronary Revascularization in Multi-vessel Disease with ST-Segment Elevation Myocardial Infarction

The aim of this study was to evaluate the health-related quality of life (HRQoL) as measured by the EQ-5D (European quality of life-5 dimensions) self-report questionnaire in patients treated with complete revascularization versus infarct artery-only revascularization at index admission.
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A Health Model Based on the Clinical Practice of Manual Therapists

Introduction: The evolution of health models occurred along with the changes of the definition of health and rehabilitation but it is still unknown the predominant model of health that fits the clinical practice of physiotherapists who work in manual therapy. Aim(s): Creation of a questionnaire to assess the health model that fits the clinical practice of physiotherapists and after application,
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A Review on Antioxidant, Anti-Inflammatory and Gastroprotective Abilities of Mango (Magnifera indica) Leaf Extract and Mangiferin

Mango (Mangifera indica Linn.) trees have been cultivated and grown in Southern and Eastern India for thousands of years and have slowly spread all over the world. For over 4,000 years various parts of mango trees including leaf and fruit pulp have been extensively used in Ayurvedic and Unani medicines.
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Designing Inter Professional Spiritual Health Care Education Program for Students of Health Sciences

Spiritual health care requires teamwork and collaboration between the doctor, nurse, psychologist, clergyman, and social worker who have completed required inter-professional spiritual health training, during and after their academic education. This study was conducted to “design inter professional spiritual health care education program for Students of Health Sciences.
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Risky Sexual Practices among Adolescents Living with HIV Accessing HIV and AIDS Care Services at Health Facilities in the Central Region of Uganda

Adolescents living with HIV in Uganda are sexually active just like their uninfected peers. With the availability of antiretroviral therapy (ART), the surviving population of adolescents prenatally infected with HIV is increasing and they are becoming sexually active.
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Screening & Awareness of Breast Cancer in an Urban Slum of Pakistan: A Pilot Study

Background: Breast cancer is the most common cancer in women across the world with low survival rates in less developed countries. Low survival rates in less developed countries can be explained mainly by the lack of early detection programs and lack of adequate diagnosis and treatment facilities.
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Mental Health Distress and Wellness among Medical Students

The aim of this article was to assess the mental distress more extensively than has been done before and to determine likely predictors of distress and well-being issues. Moreover, the significant improvement needed in connection to medical students in the context of psychological signs, symptoms of mental distress, and solutions for the students with mental health distress and wellness perspectives were addressed.
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Novel Alternative Treatment to Plasmapheresis in Evans Syndrome

Evans syndrome is a rare haematological disease characterised by concurrent occurrence of autoimmune haemolytic anaemia (AIHA) and idiopathic thrombocytopenic purpura. The autoimmune haemolysis can lead to hyperbilirubinaemia, profound anaemia and haemodynamic instability. It can be difficult to treat and when refractory to medical treatment it could necessitate emergency splenectomy. Plasmapheresis is used in refractory haemolytic anaemia to aid removal of disease causing autoimmune complexes whilst immunomodulators act to reduce autoantibody response and effectiveness. However, this is an expensive and resource intensive process that is limited to tertiary referral centres. In this case study we present a successful novel alternative for life threatening AIHA in Evans Syndrome using haemofiltration with on-going fresh frozen plasma transfusion when resources are limited or it is not an accessible method.
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Editorial Board Members Related to ALT

Gary Lee Francis

Professor
Division of Endocrinology and Metabolism
Medical College of Virginia
United States

Steve A. Maxwell

Associate Professor
Department of Molecular and Cellular Medicine
Texas A&M Health Science Center
United States

Ramesh C. Gupta

Department of Chemistry
Nagaland University
India

Majeda Al-Farajat

Director
Quality and Patient Safety
Prince Sultan Cardiac Center
Saudi Arabia

Mehdi Vosoughi

Assistant Professor
Department of environmental health engineering
Ardabil University of Medical Sciences
Iran

Michael Gibson

Associate Professor
Department of Medicine
Case Western Reserve University
United States

Joseph Pergolizzi

Adjunct Assistant Professor
Department of Medicine
Johns Hopkins University
United States

ADRIAN M. BARANCHUK

Associate Professor
Department of Biomedical and Molecular Sciences
Queen’s University
Canada

Jayasimha Rao

Associate Professor
Jefferson College of Health Sciences
Department of Medicine
USA

NAZMUL HOQUE

Assistant Professor
Department of Gynecology, Obstetrics and Reproductive Health
Bangabandhu Sheikh Mujibur Rahman Agricultural University
Bangladesh
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