Articles Related to APCI
Ion Mobility Spectrometry: A Tool in the Forensic Science for the Post Detonation Residue Analysis
The emergent threat of terrorism activities has caused an urgent need of improved forensic explosive analysis. Complex matrices, limited samples, and confusing interpretations serve as challenges for a forensic chemist in order to link the evidence to the perpetrator of the crime.
Development and Optimization of an LC-MS/MS Method for Dosage Form of Ergocalciferol (Vitamin D2 ) in Human Plasma
Accurate measurement of ergocalciferol in biological samples has become easier using high-end mass spectra. Currently, various LCMS/MS methods have been developed to quantify ergocalciferol. Use of LC-MS/MS has accomplished to develop an accurate method that could quantify ergocalciferol in a large number of samples where it should be analyzed in the blood immediately after dosage. The objective of this study is to optimize chromatographic conditions and evaluate the LC-MS/MS method for accurate quantification of the dosage form of ergocalciferol in human plasma. Extraction and separation of ergocalciferol in human plasma was achieved using methanol liquid-liquid extraction and by a reverse phase C8 column, respectively