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Articles Related to Acquired Factor XII Deficiency

Acquired Factor XII Deficiency in a Patient with Schizophrenia

We report a 50-year-old man who presented schizophrenia and an abnormal coagulation profile indicative of an inhibitor. Clinical experiments demonstrated prolonged partial thromboplastin time along with acquired factor XII deficiency and a positive anticoagulant antibody. To the best of our knowledge, the coexistence of schizophrenia and anticoagulant antibody with deficiency of coagulation factor XII is extremely rare that has not previously been reported. This patient has also indicated the paraplegia associated with spinal tuberculosis along with the loss of bladder and bowel control. Herein, we present the case of a chronic schizophrenia patient who developed the anticoagulant antibody and abnormally low serum levels of factor XII.
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