Articles Related to Adenocarcinoma
Pancreatic cancer carries one of the worst prognoses in the United States. It is the fourth leading cause of cancer-related death in the United States and second after colorectal cancer in digestive system cancer-related death. Early detection is the key to improving its prognosis. Surgical resection is the only curative treatment, but even after margin-negative resection, the 5-year survival rate is still 30%. The following case presents a fascinating diagnosis of pancreatic cancer. Despite an initial diagnosis of pancreatitis, negative cytology, tumor markers, and imaging suggestive of intraductal papillary mucinous neoplasm (IPMN), this patient underwent surgical resection that later revealed pancreatic adenocarcinoma of the tail. This article highlights certain imaging modalities and characteristics that are essential in the diagnosis of pancreatic adenocarcinoma, in an effort to guide management of similar cases, with hope it leads to better outcomes.
Rare Adnexal Carcinomas: Series of Four Cases Treated at the Ibn Rochd University Hospital of Casablanca
Cutaneous adnexal carcinomas are rare cutaneous malignant adnexal tumors derived from eccrine and apocrine sweat glands, follicular structures and sebaceous glands. They represent less than 1% of cutaneous cancers Porocarcinoma and hidradenocarcinoma are two main types of eccrine sweat carcinomas of unknown pathogenesis characterized by their clinicopathological diversity.
Chronic urticaria is a common condition but its etiology can sometimes be serious. A variety of causes has been reported to induce urticaria, like food, infections, drugs or environmental factors. Although an association between chronic urticarial and malignancy has been occasionally reported, such association remains controversial because it’s difficult to demonstrate it’s not just coincidental. However, various cancers have been described in connection with this skin pathology such as thyroid, pulmonary or renal carcinoma. In all of these cases, treatment of the tumor led to prompt resolution of the urticarial lesions, thus suggesting a pathogenetic relationship between the two. We report the case of a man treated for several months without success for chronic urticaria whose treatment of the recurrence of his prostate cancer has removed the skin lesions.
We report the case of a 52 year old man having no previous abdominal surgery who presented with small bowel obstruction. Computerised tomography showed mid jejunal obstruction, however, the cause of the obstruction could not be diagnosed radiologically. Laparotomy was performed and the obstruction was found to be due to a small annular jejunal tumour.
Primary small cell lung cancer (SCLC) showing epidermal growth factor receptor (EGFR) mutation is extremely rare. Transformation into SCLC has been reported as an evolution of lung adenocarcinoma acquiring resistance to EGFR tyrosine kinase inhibitors (TKI) and is considered to be a rare resistance mechanism of EGFR-TKI therapy.
Effect of Neoadjuvant Chemoradiotherapy on Pathologic Stage and Survival in Patients with Locally Advanced Esophageal Cancer
The treatment of resectable stages of esophageal cancer often involves pre-operative concurrent chemoradiotherapy. This study aims to evaluate the effect of cisplatin/5-fluorouracil (5-FU)-based neoadjuvant chemoradiotherapy on pathologic stage and survival in patients with locally advanced esophageal cancer.
The aim of this project was to evaluate the influence of inflammatory cytokines IL-1β and IL-8 on gastric epithelial-mesenchymal transition in gastric epithelial cells.
Image-Guided Radiotherapy Using MV for Prostate Cancer: A Correlation Analysis between Electronic Portal Imaging with Fiducial Markers and Cone Beam CT
IGRT combined with three-dimensional conformal radiation therapy (3D CRT) and intensity-modulated radiation therapy (IMRT) is gaining quick acceptance in radiotherapy treatment of prostate cancer [1-4]. The advantage of this technique is that it localizes the target volume accurately, thus increasing precision in treatment delivery.
Langerhans Cell Histiocytosis in a Patient with Lynch Syndrome (Hereditary Non Polyposis Colorectal Cancer)
A fifty three year old white female smoker with Lynch Syndrome was receiving adjuvant chemotherapy for node positive caecal adenocarcinoma. Interval investigations demonstrated a second primary gastric cancer with bilateral pulmonary nodules of indeterminate significance. Lung biopsy revealed Langerhans cell histiocytosis (LCH).
A retrospective analysis was conducted on 8466 gastric cancer patients from different age groups treated in Minsk City Clinical Oncological Hospital from 1998 to 2013. Of these, 72 (0.85%) patients were under the age of 30, 72.2% of which were diagnosed with clinical stage IV cancer
A seventy five year male presented with acute onset right foot pain and swelling. Plain imaging revealed a lytic area in the medial and middle cuneiform bones of the right foot. Background history of resected pancreatic cancer and current presentation were consistent early diffuse disease recurrence of a pancreatic primary tumour. The presenting feature in this case was of symptomatic acrometastases, that is, metastases to the feet.
Esophageal carcinoma is the eighth most common cancer, and the sixth most common cause of cancer-related deaths worldwide. Esophageal carcinomas in developing nations account for more than 80% of the total cases and deaths. Esophageal cancer can arise as esophageal squamous cell carcinoma (ESCC) or esophageal adenocarcinoma (EAC), which have distinct etiological and pathological characteristics. ESCC is the most common histological type of esophageal cancer in the Eastern world, and its incidence remains stable. In contrast, the epidemiology of esophageal cancer in developed nations has dramatically changed over the past 40 years. Forty years ago, ESCC accounted for more than 90% of esophageal cancer cases in the United States. However, adenocarcinoma has now become the leading type of esophageal cancer in the United States, representing 80% of cases.
Cutaneous metastases from abdominal malignancies are rare and have been reported in less than 5% of patients . Furthermore, metastases in patients suffering from colorectal neoplasia are even rarer entity. Tan et al, among 2538 of the new cases of colorectal cancer over the period of 6 years, reported only 3 cases (0.1%) with cutaneous deposits . Presentation varies from cutaneous or subcutaneous small nodules, rash or large fungating lesions [1-4]. Inevitably, their presence implies the disease progression, and poor prognosis with the reported survival between 1 to 34 months [2,3,5].
Gastric Type Adenocarcinoma with Fundic Gland Differentiation in the Duodenum Resected by ESD (Endoscopic Submucosal Dissection)
Gastric type adenocarcinoma with fundic gland differentiation (GA-FG) has been reported as a new, rare, chief cell differentiation composed carcinoma. Clinicopathologically, it exists on the gastric cardia/fundus, with low proliferative activity and low-grade malignancy. Until now, there has been no report of this GA-FG type cancer in the duodenum.
Metastatic gastric tumors (MGTs) mean the tumor cells that attack the stomach and grow there through blood vessel, lymph vessel, and other pathway, consistent with the primary tumor in phenotype, which are clinically uncommon, and information on MGTs is generally limited to single case reports. Here we present a clinical series of 8 cases with MGTs, in attention to discuss the clinical characteristics, diagnosis and treatment, and prognosis of MGTs.