Articles Related to Adherence
Adherence to Antiretroviral Medication and Factors Affecting it Among HIV-- Positive Patients Receiving it at Adama General Hospital
Before the development of highly active antiretroviral medication, AIDS and related illnesses caused a great deal of suffering and death. All of the AIDS-related morbidities and mortality have considerably decreased thanks to modern medication, especially in industrialized nations. However, this accomplishment is still elusive in underdeveloped nations, particularly in those in sub-Saharan Africa. This failure can be attributed to a number of factors. Poverty, ignorance about the treatment, and inadequate therapy adherence are at the top of this list.
Short-Term Usage Time and Rate of CPAP Predict Long-Term CPAP Adherence in Patients with Obstructive Sleep Apnea
Objective: Obstructive sleep apnea (OSA) is a highly prevalent disease associated with various morbidities worldwide.
Although continuous positive airway pressure (CPAP) is the cornerstone of therapy, adherence to CPAP directly affects
its efficacy. Methods: We retrospectively investigated consecutive patients who were diagnosed with OSA and placed on CPAP the-
rapy within an approximate ten-year period. Using patient characteristics and short-term usage, the predictors of adhe-
rence to CPAP were evaluated.
Level of Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in Ekiti State
Introduction: The use of anti-retroviral drugs slows down disease progression in Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) and this has improved the quality of life and life expectancy of Persons Living with HIV/AIDS (PLWHA). However, optimum use of antiretroviral drugs (adherence) by PLWHA is the key to achieving viral load suppression and preventing drug resistance in them.
Objective: This study determined the level of adherence to Anti-Retroviral Therapy (ART) among PLWHA in Ekiti State.
Methodology: A cross-sectional study was conducted on 320 PLWHA in Ekiti State University Teaching Hospital, Ado-Ekiti and 300 PLWHA in Federal Teaching Hospital, Ido-Ekiti aged 18 years and above using ARV for at least six months prior to the study. Quantitative data were collected from the participants using a structured questionnaire while sixteen in-depth interviews were conducted among purposively selected PLWHA in both study centres to further elicit qualitative information on determinants of adherence. Quantitative data were analyzed with SPSS 22 using descriptive statistics while content analysis was used for qualitative data. Regression analysis was done to identify determinants of adherence at p value < 0.05.
Results: About 60% of the PLWHA had high level of ART adherence while 18.9% had low adherence. Most of the respondents were female (66.0%), married (76.1%) and Christians (89.4%) and had post-secondary education (43.4%). Respondents’ age (X2=32.483), educational status (X2=2.473), marital status (X2=40.083), occupation (X2=57.951) and distance from the clinic (X2=13.181) significantly influenced the level of adherence. Patient factors such as forget timing of the medication, pill burden and feeling better, psychosocial factors like stigmatization, non-disclosure of status and depression; and healthcare factors such as long clinic waiting time and absence of support are some of the barriers to optimum ART adherence.
Conclusion: Counseling on drug adherence and psycho-social support to PLWHA will further improve their level of adherence to medication.
Factors Influencing Adherence to Hydroxyurea Treatment Among Children with Sickle Cell Disease at the Mother and Child Center of the Chantal Biya Foundation
Introduction: Sickle cell disease (SCD) is a genetic hemoglobin disease for which there are many treatment options. Evidence supports the efficacy and cost-effectiveness of hydroxyurea (HU). Nevertheless, its use and adherence to treatment remain suboptimal, hence, the necessity to assess the factors influencing this observance.
Objectives: The objective was to evaluate the factors influencing observance to HU in children with sickle cell disease from the Mother and Child Center of the Chantal Biya Foundation (MCC of the CBF).
Materials and Methods: This was a descriptive and analytical cross-sectional study from January to June 2020. Children on HU for at least six months, and followed up at MCC of the CBF were included. Data collection was done using a pre-tested questionnaire. The level of compliance was assessed using the Morisky’s observance grid, where 8 points was considered as “good”; 6-7 points as “fair”, and <6 as “poor”. Data were stored in CSPro version 7.0 software, and subsequently analyzed using the SPSS version 20.0 software.
Results: Of 142 patients recruited, the level of patient observance was considered “good” in 2.1%, fair in 26.1% and poor in 71.8%. Logistic regression analyses suggested that using hydroxyurea to prevent complications was the only factor that favored good medical adherence [OR=0.37; CI (0.14-0.987)] (p=0.047). Poor compliance was mainly associated with the fear of infertility and and other sides effects associated with the use of HU.
Conclusion: Children with SCD in this study have poor compliance with HU. Implementing IEC sessions would make it possible to raise patient/parent awareness and reverse this trend.
The development and validation of the Factors Affecting Adherence Scale in Greece
Despite hypertension is a major cardiovascular risk factor; only a few patients are adherent to therapy. Therefore, it is essential the acknowledgment of factors affecting adherence. The development and validation of a scale assessing factors affecting patients’ adherence to the therapeutic regimen.
Determinants of Medication Adherence in Nausea and Vomiting of Pregnancy
A major issue in adherence to medical treatment in nausea and vomiting of pregnancy (NVP) is mothers’ fear of perceived teratogenic damage. The objective of this study was to identify predictors of adherence to medication treatment in NVP. A prospective cohort study based on telephone interviews among women who experienced NVP and counseled by
Motherisk Israel NVP Helpline, located in a teratology information service. The consultation was divided into pharmacological and non-pharmacological recommendations. Data on adherence to medications and pregnancy outcomes were collected during telephone follow up interviews which were carried out soon after the birth of the child.
Neuropsycological Function, Insight, and Treatment Adherence among Patients with Schizophrenia
Research has suggested that poor insight in patients with schizophrenia is associated with poorer treatment compliance. One factor ontributing to poor insight may be neurocognitive deficits. The aim of the current study is to explore the relationship between cognitive insight, clinical insight, treatment adherence, executive functions and sustained attention within patients with schizophrenia. The study was conducted on 41 patients with schizophrenia using the Beck cognitive insight scale, the schedule for assessment of insight, the drug attitude inventory and two neuropsychological tests.
The Psychosocial Factors that Influencing HIV-AIDS Antiretroviral Treatment Adherence
The socio-cultural context of illness has become a major research area, and it has made significant contributions to our understanding of the socio-cultural dimensions of illness. In this article, we briefly trace the roots of a socio-cultural approach to illness, and we present some of the key findings of socio-cultural organized under main themes. Adherence to antiretroviral therapy drugs in the treatment of HIV infection is complicated because of many psychosocial factors. The aim of the study was to investigate the psychosocial factors involved in non-compliance with ART among people infected with HIV in Alert Hospital in Ethiopia.
Challenges in the Pharmacological Management of Non Hodgkin’s Lymphoma in Children in the Maintenance Phase of Therapy at Kenyatta National Hospital
Non Hodgkin’s lymphoma is an extremely chemo sensitive with a five year event free survival of greater than 90% in developed countries and a one year survival rate of 40-50% in developing countries.
Pregnancy after Novasure® Endometrial Ablation: Two Cases and a Literature Survey
NovaSure® endometrial ablation is a successful therapy for patients with heavy menstrual bleeding who do not want to preserve fertility. However, endometrial ablation is not a contraceptive treatment. We report two cases of pregnancy after NovaSure® endometrial ablation. Case 1 is a pregnancy in a 44-year old woman.