Articles Related to Cardiomyopathy
Cisplatin-Gemcitabine Related Cardiomyopathy in Non-Small Cell Lung Cancer NSCLC Patient: A Case Study
Gemcitabine is a pyrimidine analog and cisplatin is a platinum agent, they are usually combined to form a chemotherapeutic doublet used to treat different types of oncological cancers, including non-small cell lung cancer (NSCLC). Although these agents are not known to cause such events, few cases related to possible cardiotoxicity side effects have been reported ; including angina, chronic heart failure, arrhythmias, and cardiac ischemia. A 52-year-old African male presented with Stage IV lung adenocarcinoma metastatic to the bone, pleura and lymph node, EGFR wild type. Patient has a history of hypertension, diabetes, and atrial fibrillation and on rate control medications. He was treated initially with cisplatin-gemcitabine, after which he developed cardiomyopathy.
Investigate the use of cardiac resynchronization therapy (CRT) in cancer patients with heart failure (HF); assess factors associated with ischemic and non-ischemic HF. Many newer cancer therapies are cardiotoxic; thus, the incidence of HF has been increasing in this high-risk patient population. CRT has beneficial effects on morbidity, mortality, and left ventricular function in patients with non-ischemic cardiomyopathy, yet cancer patients and survivors who develop severe HF and are eligible for CRT often does not receive it.
54-year-old gentleman with a previous medical history consistent of recurrent headaches, hypertension, dilated cardiomyopathy, hypercholesterolemia and recurrent renal calculi. Over a one-year period, he gradually developed worsening headaches associated with intermittent blurred vision, generalized aches and pains, mild cognitive impairment, and several episodes of focal upper and lower limb weakness.
Acquired heart diseases such as myocarditis, cardiomyopathies and rheumatic heart diseases are important non-communicable diseases responsible for morbidity and mortality in children.
Dilated Cardiomyopathy is the most common form of the cardiomyopathies in children accounting for a significant cause of morbidity and mortality as well as a common indication for heart transplant.
Methamphetamine is one of the most commonly abused illegal stimulants and causes the release of dopamine, norepinephrine and serotonin. These neurotransmitters trigger vasospasm, causing persistent tachycardia, hypertension, and direct myocardial toxicity. Moderate usage of methamphetamine can increase cardiac output and myocardial contractility. However, larger doses can cause depression of the myocardium.
Could Non-Linear Heart Rate Variability Analysis of Short RR Intervals Series Give Clinically Valuable Information in Heart Disease?
New analytic methods based on nonlinear system theory have been developed to characterize the nonlinear features in HR dynamics. It is known from long time series (24h ECG recordings) that patients with chronic heart failure or stable coronary heart disease have altered fractal organization in heartbeat dynamics. During such long-time series, many confounding could limit the assessment of autonomic functions.
Editorial Board Members Related to Cardiomyopathy
University of Toledo
University of Toledo