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Articles Related to Coagulopathy

Acquired Factor XII Deficiency in a Patient with Schizophrenia

We report a 50-year-old man who presented schizophrenia and an abnormal coagulation profile indicative of an inhibitor. Clinical experiments demonstrated prolonged partial thromboplastin time along with acquired factor XII deficiency and a positive anticoagulant antibody. To the best of our knowledge, the coexistence of schizophrenia and anticoagulant antibody with deficiency of coagulation factor XII is extremely rare that has not previously been reported. This patient has also indicated the paraplegia associated with spinal tuberculosis along with the loss of bladder and bowel control. Herein, we present the case of a chronic schizophrenia patient who developed the anticoagulant antibody and abnormally low serum levels of factor XII.
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Case Report of Severe Preeclampsia and Associated Postpartum Complications

Preeclampsia is clinically defined by hypertension and proteinuria, with or without pathologic edema that occurs after 20 weeks’ gestation, but can also present up to 4-6 weeks post-partum. Worldwide, incidence of preeclampsia is 5-14 percent of all pregnancies, while severe preeclampsia can develop to about 25 percent of all cases of preeclampsia.
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Pregnant Patients with Deep Venous Thrombosis: Management and the Incidence of Thrombophilic Risk Factors

There is lack of knowledge about anticoagulant therapy in pregnancy and an acceptable guide for their use is based on case series and the opinion of scientists. For this reason, we carried out a study on pregnant women suffering from acute deep venous thrombosis (DVT) using enoxaparin twice daily dose.
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Warfarin-Induced Tissue Necrosis (WITN): Case Report and Literature Review, A Proposed Name Change

Warfarin is the most frequently prescribed oral anticoagulant in the United States. Its indications range from treatment of deep venous thrombosis and pulmonary emboli to the prophylaxis and treatment of thromboembolic conditions associated with atrial fibrillation and cardiac valve replacement. While bleeding is the most commonly encountered complication warfarin induced skin necrosis (WISN) can be a rare complication. Extensive skin and deeper tissue necrosis may be encountered requiring multiple surgical debridement and reconstructive procedures along with the medical management.
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