Articles Related to Cognitive Function

It has been reported that tomato (Solanum lycopersicum) fruit extracts may have beneficial effects on cognition. To assess if those effects are reproducible, cognitive function was assessed using a double-blind, randomised control trial design; 17 healthy test participants were given encapsulated tomato fruit (n=8) extract (290 mg) or a placebo control (n=9). Cognition was assessed at rest and, as exercise is known to negatively impact on cognitive function, equivalent tests were also undertaken after controlled physical exertion using the Bath University Rugby Shuttle Test (45 minutes and 90 minutes exercise).

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Excessive exposure to club drug gamma-hydroxybutyric acid (GHB) would cause cognitive dysfunction in which impaired Ca2+-mediated neuroplasticity in hippocampus may play an essential role in the pathogenesis of this deficiency. Considering melatonin is positive for neuroplastic regulation, the present study aims to determine whether melatonin would exert a neuro-protective effect on cognitive function following GHB.

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