Articles Related to C%ce%bc
Movement Assessment Battery for Children-2 (MABC-2): A Cross-Cultural Comparison for Surinamese Children at 5 Years of Age
The Movement Assessment Battery for Children (MABC) is used globally to identify and describe impairments in motor development in children; however, norms for Surinamese children are lacking. We thus conducted a cross-cultural comparison for Surinamese children 5 years–5 years and 6 months using the Dutch/Flemish (NL) and United Kingdom (UK) norms of the MABC, second edition (MABC-2).
Quality of Life after Accidental Major Vascular Injury and Prolonged ICU Stay - A Case Report
Survival or mortality rate is a reasonable choice of an outcome measure for critically ill patients in intensive care unit (ICU). But it is also important to assess the impact of critical illness and peri-operative complications on health status and quality of life (QoL) after hospital discharge. The QLQ-C30 is a 30-item cancer-specific questionnaire that incorporates five functioning scales (physical, role, cognitive, emotional, and social), eight symptoms scales, perceived financial impact of the disease and a global scale [1-5].
Evaluating the Effect of Oprelvekin on Cardiac Repolarization in Subjects with Chemotherapy-Induced Thrombocytopenia: An Observational Chart Review of a Phase 2 Clinical Trial in Laredo, Texas
This study tested for the cardiac effects of Oprelvekin, recombinant human interleukin-11, a thrombopoietic growth factor, in patients afflicted with chemotherapy-induced thrombocytopenia (platelet count<50,000 cells/ul). Chart-reviews of patients fulfilling the inclusion criteria of: 18-75 yrs of age, non-myeloid malignancy, with adequate hematologic, hepatic and renal parameters and normal electrocardiograms that were enrolled in this phase 2 trial were analyzed. Patients of child-bearing potential agreed to be on a reliable form of birth control for the duration of the study. Results on 4 patients suggest that Oprelvekin does not cause atrial nor ventricular arrhythmia, a rare severe cardiac side effect, in treating patients with chemotherapy-induced thrombocytopenia.
Isolation, Identification, and Characterization of the Novel Antibacterial Agent Methoxyphenyl-Oxime from Streptomyces pratensis QUBC97 Isolate
Streptomyces species are medically, industrially, and microbiologically important bacteria that are found in soils and other habitats. Streptomyces isolates and QUBC97 were cultured on a new medium (CCG). Agar plug diffusion test showed antibacterial activity. N-butanol extracts analysed by silica thin layer chromatography (TLC), HPLC purified and identified by MS analysis. QUBC97 was identified based on morphology, PCR, and DNA sequencing of two loci.
Osteo-Articular Complications in a Pediatric Sickle Cell Disease Population - Imaging Value
Sickle cell disease (SCD) is the most frequent of a group of conditions known as haemoglobinopathies. The disease is an autosomal recessive genetic disorder, characterized by abnormal haemoglobin (Hemoglobin S) that under certain conditions polymerizes resulting in microvascular occlusions. This pictorial review illustrates the osteo-articular manifestations associated with sickle-cell disease encountered in children in our institution with at least one Haematology appointment in 2013/2014. Osteo-articular manifestations with imaging findings were reported in 28 out of 97 patients. The most frequent complications and those that required hospital care were painful vaso-occlusive crisis and femoral head osteomyelitis.
The Impact of Repeated Hb A2 Measurements on β-Thalassemia Trait Diagnosis
Hemoglobin A2 (Hb A2) is a minor component of the hemoglobin present in normal adult red blood cells, accounting for 1.5-3.5% of the total hemoglobin in healthy individuals.
A One-Year Hospital Based Prospective Study of Sickle Cell Disease from One Capital Area of Kuwait by HPLC
Haemoglobinopathies are inherited disorders of haemoglobin synthesis that are responsible for significant morbidity and mortality all over the world.
An Introduction to the Approaches of Novel Drug Delivery Systems for Acquired Immune Deficiency Syndrome (AIDS)
The currently available anti HIV agents have several drawbacks such as short half life, low bioavailability, poor CNS penetration and
retention, hepatic first pass metabolism, undesirable side effects and frequent dosing regimen.
Costimulatory Molecules CD80 and CD86 Colocalized in Neutrophil Extracellular Traps (NETs)
Neutrophil extracellular traps (NETs) have been proposed as vehicles for the sensitization of T cells by decreasing their activation threshold.
Mesenchymal Stem Cells from Different Tissues: Immune Status and Activity
Mesenchymal stem cells (MSCs) have been found in almost all tissues and due to their regenerative properties represent promising tools in cell-based therapy. Role of MSCs in tissue repair is strongly governed by their interplay with immune cells and regulating factors.
Orally Disintegrating Tablets: A Short Review
This article summarizes the advantages of orally disintegrating tablets (ODTs) as well as critical issues during evaluation of ODTs such as bioequivalence and challenges and limitations of ODTs and finally present and the future of ODTs. ODTs have received everincreasing demand and the field has become a rapidly growing area in the pharmaceutical industry.
In Vitro Models to Study Candida Albicans Biofilms
Biofilm is a common mode of fungal growth in clinical infection and Candida albicans is one of the species that are the most frequently associated with biofilm infection which has a significant impact on morbidity and mortality. In the mode of biofilm, C. albicans tends to display high resistance to body immunity and antimicrobial agents.
Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites
Ovarian cancer constitutes the second most common gynecological cancer with a five-year survival rate of 40%. Among the various histotypes associated with hereditary ovarian cancer, high-grade serous epithelial ovarian carcinoma (HGSEOC) is the most predominant and women with inherited mutations in BRCA1 have a lifetime risk of 40-60%. HGSEOC is a challenge for clinical oncologists, due to late presentation of patient, diagnosis and high rate of relapse. Ovarian tumors have a wide range of clinical presentations including development of ascites as a result of deregulated endothelial function thereby causing increased vascular permeability of peritoneal vessels.
Do Expression Profiles of Cytokines VEGF, TNF- α, IL-1β, IL-6 and IL-8 Correlate with Gallbladder Cancer?
Gallbladder carcinoma is a multifactorial disease with a complex interplay at molecular levels. Here we look at the expression of specific cytokines (TNF-α, IL-1β, IL-6, IL-8 and VEGF) in GBC patients to develop them as biomarkers of gallbladder cancer.
Fangchinoline Inhibits Breast Tumor Proliferation and Induces Apoptosis in MDA-MB-231 Cell Line in Vivo
Immunohistochemistry (IHC) was used to determine the protein levels of p27, CD117 and ki67 in tumor tissue of xenograft. After treatment of Fan, the morphologic changes were observed by DAPI staining, Hoechst staining and TUNEL detection under fluorescent microscopy.
Editorial Board Members Related to C%ce%bc
Wei-Yen Hsu
Professor
Department of Information Engineering and Management
National Chung Cheng University
Taiwan
Department of Information Engineering and Management
National Chung Cheng University
Taiwan
MASAYOSHI YAMAGUCHI
Professor
Department of Hematology and Medical Oncology
Emory School of Medicine
Emory University
United States
Department of Hematology and Medical Oncology
Emory School of Medicine
Emory University
United States
Paulo Nunes Costa Filho
School of Physical Education and Sports, Rio de Janeiro Federal University, Av. Carlos Chagas Filho, 540 - Cidade Universitária, Rio de Janeiro, RJ, 21940-901, Brazil.
Madhu K. Nair
Professor
Division of Oral and Maxillofacial Diagnostic Sciences
College of Dentistry
University of Florida
United States
Division of Oral and Maxillofacial Diagnostic Sciences
College of Dentistry
University of Florida
United States
Prof. Dr. Alireza Heidari, Ph.D., D.Sc.
Full Distinguished Professor and Academic Tenure of Chemistry.
Enrico Fermi Distinguished Chair in Molecular Spectroscopy.
Head of Cancer Research Institute (CRI).
Director of the Bio Spectroscopy Core Research Laboratory (BCRL) at Faculty of Chemistry, California South University (CSU), Irvine, California, USA.
President of the American International Standards Institute (AISI), Irvine, California, USA.
Board Member of the World Association of Theoretical and Computational Chemists (WATOC).
Suresh G. Joshi
Associate Professor
Department of Microbiology and Immunology
Drexel University
United States
Department of Microbiology and Immunology
Drexel University
United States
Michael Downing
Clinical Associate Professor
Faculty of Medicine
University of British Columbia
Canada
Faculty of Medicine
University of British Columbia
Canada