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Articles Related to DC

Global Correction of T10 Non-uniformity in mMR Breast Coil with Multiple Tube Phantom-based Technique and its Validation in Breast MRI: a Feasibility Study

Non-uniform native T1 (T10) distribution influences reliable measurement of Ktrans: a pharmacokinetic parameter (Ktrans) that quantitatively measures neovascularization of the tumor tissue that has been used for the classification of malignant breast lesions and to monitor therapy response.
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Multidetector CT Imaging of Squamous Cell Carcinoma of Buccal Mucosa

This study aims at describing the CT imaging findings and role of multidetector computed tomography (MDCT) in evaluation of squamous cell carcinoma of buccal mucosa and its staging. The imaging findings in squamous cell carcinoma (SCC) of the oral cavity allow the radiologist to accurately determine the extent and staging of disease thereby help clinicians plan appropriate treatment.
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Hand Washing: A Proposed Scoring Scale to Grade the Level of Practice of Mothers in the Community

History of hand washing as an intervention to reduce morbidity and mortality in hospitals dates back to early 1800’s and the practise has yielded good results. Increasing evidence suggesting that hand washing significantly reduced the risk of respiratory tract infections and diarrhoeal diseases, lead to the promotion of hand washing in homes as a public health intervention of choice with well documented impact.
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Atypical Femur Fracture Nonunion in a Patient with Osteogenesis Imperfecta

Here, we present a 43-year-old male with osteogenesis imperfecta (OI) with previously placed intramedullary growing rods that sustained an atypical femur fracture (AFF) following long-term bisphosphonate use. He additionally experienced a non-traumatic ipsilateral femoral neck fracture that was successfully managed with operative stabilization. Despite previous reports following successful conservative management for AFF in patients with OI, nonunion developed requiring osteotomy and surgical stabilization.
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Former Effective Immunotherapy without Adverse Events of Inoperable Epithelial Ovarian Cancers and a Prospect for the Immune Prophylaxis

Current cancer treatments by immune checkpoint blockades are limited due to severe adverse events caused by alteration of the immune system required for homeostasis of normal tissues. Common cancer chemotherapy alters the quality of patients’ lives. Platinum-based treatment can lead to severe neurotoxicity with chronic debilitation. Additionally, survival of patients with epithelial ovarian cancers (EOCs) has remained poor despite extensive cytoreductive surgery, high dose chemotherapy, checkpoint blockades and immunotherapies effective in some other types of cancer. The pathobiology of EOC cancer stem cells (CSCs) is not well understood. Observations demonstrate that EOCs exhibit in vivo two distinct CSC types - perivascular diploid CSCs dividing asymmetrically with the help of the host suicidal CD8+ T cells, and haploid CSCs at the cancer abdominal surface originating from meiosis I cytokinesis of bulk surface cancer cells. The perivascular CSCs contribute to the cancer cell bulk and, via left ovary venous blood, can cause EOC liver metastases. Haploid CSCs released from the bulk cancer surface cause the common pelvic and abdominal EOC spread. Former elimination of the host antibodies blocking T cell effectors by intermittent doses of cyclophosphamide exhibiting significant immunomodulatory anticancer effects, facilitation of the immune system reactivity against alloantigens of cancer cells by blood transfusions, and augmentation of anticancer immunity by bacterial toxins, resulted during the subsequent treatment-free period into rejection of inoperable EOCs without any adverse events during the treatnment. To help prevent cancer relapses, patients treated for advanced primary epithelial cancers should be considered as candidates for continuously stimulating immune anticancer activity by treatments such as daily metformin and weekly lentinan consumptions.
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Bubonic Plague Outbreak Investigation in the Endemic District of Tsiroanomandidy - Madagascar, October 2014

Plague remains a major public health problem in Madagascar. Faced with reports of plague cases and deaths in Tsiroanomandidy district, we performed an investigation in October 2014.Our aim was to describe the plague outbreak and to improve the national plague control strategies. We used the National plague control program case definition. We identified cases from outpatient registers and collected socio-demographic and clinical information. Plague circulation was determined through a retrospective environmental survey of rodents and vectors.
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Retinoblastoma: A Retrospective Study of 27 Cases in University Hospital of Lubumbashi-RDC

We conducted a retrospective study on 27children with retinoblastoma in the Lubumbashi University Hospital between January 2008 and October 2012. Al cases were diagnosis clinically and 11 cases were confirmed by histology.
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Responses and Survival under Pegylated Interferon α2a Treatment for Patients with Post-MPN Acute Myeloid Leukemia and Acute Panmyelosis with Myelofibrosis

We report here for the first time the efficacy of pegylated interferon α2a (Peg-Ifn) as a therapy for patients with myelofibrosis and high blast counts. We treated four patients who were in an accelerated phase of myeloproliferative neoplasms or acute panmyelosis with myelofibrosis using only this drug.
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Community Perception towards Traditional Healers and Health Centers on Management of Dog Bites and its Relation with Veterinary Public Health Activities

A survey was conducted to investigate whether the community uses traditional healers or modern health centers after exposure to dog bites and veterinary public health responses on the issues in Arba Minch, Ethiopia. Two stage cluster and simple random sampling procedures were employed to select inhabitants and other target study population for this study.
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Hirschsprung’s Disease in Adult Treated by Coloprotectomy and Colo-Anal Anastomosis

Hirschsprung’s disease is a rare pathology Most cases become manifest during the neonatal period, but in rare instances, the disease is initially diagnosed in adult patients.
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How Should we Screen Overweight and Obese Adolescents for Risk of Type 2 Diabetes in Large Public Health Initiatives?

To develop a valid method to identify insulin resistance (IR) in overweight and obese adolescents without requiring a fasting blood sample.
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Relationship between Body Weight and Self-Esteem: A Study of Young Men and Women in Iran

Obesity and the side effects of weight gain among Iranian females are significantly higher compared to males. In addition, the trend of overweight and obesity among Iranian adolescents in particular is increasing.
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Addressing the Risk of Product Fraud: A Case Study of the Nigerian Combating Counterfeiting and Sub-Standard Medicines Initiatives

Combating counterfeit medicines requires a new and unique crime scene investigation and forensic science approach. The “crime scene” is both at the production of the counterfeit product anywhere in the world and simultaneously at the packaged product in a consumer’s hand.
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Clinical Evaluation of 762 Single-Tooth, Locking-Taper Implants: A Prospective Study with 1- to 12-Years of Follow-Up

The aim of this study was to evaluate the survival rate, complications and marginal bone loss of single-tooth lockingtaper implants.
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Primary Angiitis of the Central Nervous System a Riddle, Wrapped in a Mystery, inside an Enigma

54-year-old gentleman with a previous medical history consistent of recurrent headaches, hypertension, dilated cardiomyopathy, hypercholesterolemia and recurrent renal calculi. Over a one-year period, he gradually developed worsening headaches associated with intermittent blurred vision, generalized aches and pains, mild cognitive impairment, and several episodes of focal upper and lower limb weakness.
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Editorial Board Members Related to DC

Moinuddin Sarker

Natural State Research Inc.
Stamford, Connecticut
United States

Wai Yee Chan

Professor of Biomedical Sciences and Director
School of Biomedical Sciences
The Chinese University of Hong Kong
Hong Kong

GHASSAN M. MATAR

Professor
Department of Experimental Pathology, Immunology & Microbiology
Faculty of Medicine
American University of Beirut
Lebanon

Loai Aljerf

Professor
Department of Basic Sciences
Faculty of Dental Medicine
Damascus University
Syria

Sherifa Ahmed Hamed

Professor
Department of Neurology and Psychiatry
University of Assiut
Egypt

Konstantin N Konstantinov

Professor
Department of Internal Medicine
University of New Mexico
United States

ALI H. MOKDAD

Professor of Global Health
Institute for Health Metrics and Evaluation (IHME)
University of Washington
United States

Maythem M Saeed

Adjunct Professor
Department of Radiology
School of Medicine
University of California
United States

SHANKAR M. L. SASTRY

Professor
Department of Mechanical Engineering and Materials Science
Washington University, St. Louis
United States

PUNAM OHRI-VACHASPATI

Associate Professor
School of Nutrition and Health Promotion
Arizona State University
United States
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