Articles Related to DC

SARS-CoV-2 can reach the central nervous system through the vagal nerve. Microbiota may favour or prevent viral spread. Assess whether auricular transcutaneous vagus nerve stimulation (ATVNS) may favour the occurrence of mild-COVID-19 or the recurrence of herpes simplex type 1. 749 patients were included. 195 patients were recommended and comply with ATVNS. 67 patients of the ATVNS group experienced mild-COVID-19 (34.3%) versus only 28 in the not-recommended ATVNS group (525 patients; 5.3%). A similar percentage was observed in the non-compliant ATVNS group (one case for 29 patients; 3.4%) [p<0.001].

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Non-uniform native T1 (T10) distribution influences reliable measurement of Ktrans: a pharmacokinetic parameter (Ktrans) that quantitatively measures neovascularization of the tumor tissue that has been used for the classification of malignant breast lesions and to monitor therapy response.

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This study aims at describing the CT imaging findings and role of multidetector computed tomography (MDCT) in evaluation of squamous cell carcinoma of buccal mucosa and its staging. The imaging findings in squamous cell carcinoma (SCC) of the oral cavity allow the radiologist to accurately determine the extent and staging of disease thereby help clinicians plan appropriate treatment.

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History of hand washing as an intervention to reduce morbidity and mortality in hospitals dates back to early 1800’s and the practise has yielded good results. Increasing evidence suggesting that hand washing significantly reduced the risk of respiratory tract infections and diarrhoeal diseases, lead to the promotion of hand washing in homes as a public health intervention of choice with well documented impact.

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Here, we present a 43-year-old male with osteogenesis imperfecta (OI) with previously placed intramedullary growing rods that sustained an atypical femur fracture (AFF) following long-term bisphosphonate use. He additionally experienced a non-traumatic ipsilateral femoral neck fracture that was successfully managed with operative stabilization. Despite previous reports following successful conservative management for AFF in patients with OI, nonunion developed requiring osteotomy and surgical stabilization.

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Current cancer treatments by immune checkpoint blockades are limited due to severe adverse events caused by alteration of the immune system required for homeostasis of normal tissues. Common cancer chemotherapy alters the quality of patients’ lives. Platinum-based treatment can lead to severe neurotoxicity with chronic debilitation. Additionally, survival of patients with epithelial ovarian cancers (EOCs) has remained poor despite extensive cytoreductive surgery, high dose chemotherapy, checkpoint blockades and immunotherapies effective in some other types of cancer. The pathobiology of EOC cancer stem cells (CSCs) is not well understood. Observations demonstrate that EOCs exhibit in vivo two distinct CSC types - perivascular diploid CSCs dividing asymmetrically with the help of the host suicidal CD8+ T cells, and haploid CSCs at the cancer abdominal surface originating from meiosis I cytokinesis of bulk surface cancer cells. The perivascular CSCs contribute to the cancer cell bulk and, via left ovary venous blood, can cause EOC liver metastases. Haploid CSCs released from the bulk cancer surface cause the common pelvic and abdominal EOC spread. Former elimination of the host antibodies blocking T cell effectors by intermittent doses of cyclophosphamide exhibiting significant immunomodulatory anticancer effects, facilitation of the immune system reactivity against alloantigens of cancer cells by blood transfusions, and augmentation of anticancer immunity by bacterial toxins, resulted during the subsequent treatment-free period into rejection of inoperable EOCs without any adverse events during the treatnment. To help prevent cancer relapses, patients treated for advanced primary epithelial cancers should be considered as candidates for continuously stimulating immune anticancer activity by treatments such as daily metformin and weekly lentinan consumptions.

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Plague remains a major public health problem in Madagascar. Faced with reports of plague cases and deaths in Tsiroanomandidy district, we performed an investigation in October 2014.Our aim was to describe the plague outbreak and to improve the national plague control strategies. We used the National plague control program case definition. We identified cases from outpatient registers and collected socio-demographic and clinical information. Plague circulation was determined through a retrospective environmental survey of rodents and vectors.

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We conducted a retrospective study on 27children with retinoblastoma in the Lubumbashi University Hospital between January 2008 and October 2012. Al cases were diagnosis clinically and 11 cases were confirmed by histology.

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We report here for the first time the efficacy of pegylated interferon α2a (Peg-Ifn) as a therapy for patients with myelofibrosis and high blast counts. We treated four patients who were in an accelerated phase of myeloproliferative neoplasms or acute panmyelosis with myelofibrosis using only this drug.

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A survey was conducted to investigate whether the community uses traditional healers or modern health centers after exposure to dog bites and veterinary public health responses on the issues in Arba Minch, Ethiopia. Two stage cluster and simple random sampling procedures were employed to select inhabitants and other target study population for this study.

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Hirschsprung’s disease is a rare pathology Most cases become manifest during the neonatal period, but in rare instances, the disease is initially diagnosed in adult patients.

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To develop a valid method to identify insulin resistance (IR) in overweight and obese adolescents without requiring a fasting blood sample.

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Obesity and the side effects of weight gain among Iranian females are significantly higher compared to males. In addition, the trend of overweight and obesity among Iranian adolescents in particular is increasing.

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Combating counterfeit medicines requires a new and unique crime scene investigation and forensic science approach. The “crime scene” is both at the production of the counterfeit product anywhere in the world and simultaneously at the packaged product in a consumer’s hand.

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The aim of this study was to evaluate the survival rate, complications and marginal bone loss of single-tooth lockingtaper implants.

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