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Articles Related to Diagnosis

An Unexpected Diagnosis of Plasmacytoma of The Thyroid: A Case Report and Review of The Literature

Plasmacytoma is a malignant proliferation of plasma cells that can arise in the bone marrow (osseous) and in the soft tissues. Extramedullary plasmacytomas most commonly occur in the upper respiratory tract. Thyroid involvement is rare. In this report, we describe a new case plasmacytoma of the thyroid gland in a 60-year-old man with a history of multinodular goiter present for several years and an unexpected rapid increase of the mass associated to dysphagia, dyspnea, and dysphonia. Histopathological examination of surgical specimen, along with immunohistochemical studies, unexpectedly led to the diagnosis of plasmacytoma. We also briefly summarize the last 30 years of literature on thyroid plasmacytoma and review the salient characteristics of this rare condition.
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Detection of a Rheumatic Factor (RF,) Anti- Cyclic Citrullinated Peptides (Anti CCP) Antibodies and C- Reactive Protein (CRP) in Diagnosis and Prognosis of Rheumatoid Arthritis

Introduction: Rheumatoid arthritis ( RA)is an autoimmune and inflammatory disease. It is characterized by arthrosynovitis with resultant joint destruction . So, an early clinical diagnosis along with simple serological tests like anti CCP antibodies, C –reactive protein ( CRP) and Rheumatoid factor (RF) play an important role .An attempt was made to study and compare these parameters in OPD and IPD RA patients in our hospital setup, VMMC and Safdarjung Hospital , New Delhi. Aims and Objectives: To study the role of RF , Anti-CCP antibodies and CRP in early detection and prognosis of Rheu- matoid arthritis. Materials and Methods: A Total of 440 samples were studied from January 2018 to December 2020 (3years). Correlation between Rheumatoid factor(RF) ,anti CCP antibodies and CRP in suspected RA patients from various departments like PMR , Orthopaedics , Medicine, Obstetrics and Gynaecology and Paediatrics was attempted. RF and CRP was performed using latex agglutination test and anti CCP antibody by ELISA. Results and Conclusion: Of 440 samples tested, all the factors were positive in 87 patients . Anti CCP and RF alone was seen in 32 patients. RF and CRP positive in 49 patients, RF alone in 22 patients. In 250 patients all the tests were negative. So, Anti CCP along with RF and CRP showed a better positive predictive value in patients of Rheumatoid arthritis. But positivity of these parameters even in patients who lack sign and symptoms also aids in better diagnosis, treatment and prognosis.
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Diagnosis and Surgical Treatment of Patients with Closed Pancreatic Injuries

Diagnosis and choice of therapeutic rational tactics in patients with closed pancreatic injuries still remain and actual problem of urgent abdominal surgery. The results of treatment of 70 patients with pancreatic injuries being treated in a surgical department of RSCUMA of Uzbekistan Public Health and its branches during 2009-20021 with analyzed. Intraoperative inspection of omental bursa is still a single reliable method to reveal injuries to the pancreas. Depending on the character and localization the differ following kinds of surgical treatment of pancreatic injuries were used: based on adequate drainage of the impaired zone; removal of lifeless pancreatic tissues; restoration of passage or rational derivation of pancreatic juice. It is necessary to underline that in all cases of pancreatic injuries antisecretory, antianzymatic, antibacterial and desintoxicating therapy must be carried out.
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Confirmation Bias and Restorative Justice in The Setting of a Missed Diagnosis

One factor underlying medical errors in “confirmation bias,” the tendency to interpret new evidence as confirmation of one’s existing beliefs or theories. When a medical error occurs, the physician has a moral duty to examine the factors which lead to its occurrence, to discuss these factors with the patient who suffered the error, and to perform their due diligence to prevent the error from occurring again. Restorative Justice is a form of collaborative decisionmaking including all parties involved in a precipitating event, including the perpetrators, victims, and stakeholders. We report on a case in which confirmation bias played a major role in misdiagnosis followed by the application of Restorative Justice principles to address the consequent mistrust between the physician and patient.
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The Heel Fat Pad Syndrome - A Neglected Diagnosis

The heel fat pad cushioning is the result of its structure, shape, thickness. Its morphological modifications due to changes in the amount or distribution of the loads normally sustained by the foot can be disturbed and can result in heel pain. The heel fat pad was found to have a crest on its anterior dorsal surface, flanges on both sides and posteriorly, and a thick portion that reached and covered the posterior surface of the calcaneus and the Achilles tendon insertion. Its anterior internal portion is thinner, and a lump of fat is consistently present in this region [1].
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Relationship between Body Mass Index and Diagnosis of Obesity in the Military Health System Active Duty Population

The overall rate of obesity is rising in the United States; this is also reflected in the military population. It is important that providers appropriately diagnose obesity and discuss treatment options with their patients.
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Latent Fingerprint on Human Skin: A Silent Diagnosis

Fingerprints are one of the most valuable evidence due to their uniqueness.
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A MRI Diagnosis of Congenital Urogenital Anomalies in 27 Years Old Man

Congenital anorchia is an uncommon clinical condition. Etiology and pathogenetic mechanisms are often unknown. Although some patients with anorchia present with ambiguous external genitalia or micropenis, most have a normal phenotype. XY Disorders of Sex Development classifications are numerous and success rate in establishing a precise diagnosis is far lower than in XX karyotype.
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Should the Lateral Chest Radiograph be a Routine Projection in the Diagnosis of Pneumonia in Children: A Narrative Review?

Chest x-rays (CXR) are frequently used in the diagnosis of pneumonia in pediatrics patient. The lateral projection produces more than double the effective patient dose than the frontal (anterior-posterior (AP)/ posterior-anterior (PA)) projection in CXR series, with potentially little assistance in diagnosing disease.
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Squamous Cell Carcinoma of the External Auditory Canal: Case Report

Squamous cell carcinoma of the external auditory canal may masquerade as an infective process causing late diagnosis. A delay in treatment as a result of missed diagnosis would carry a poor prognosis as the disease progresses to an advanced stage. We present a case of a man with history of chronic otorrhea, who developed left sided otalgia associated with hearing loss. otoscopic examination shows a mass in her left ear and pus discharge which was initially treated as an infection. The biopsy of the mass was proven to be squamous cell carcinoma. High index of suspicion is necessary when encountering patients presenting with a mass in the ear canal with prior history of chronic otorrhea or cholesteatoma. Proper tissue biopsy is crucial. Early diagnosis is required for better prognosis for the patient.
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Importance of Complete Clinical History in the Management of Parakeratinized Odontogenic Keratocyst: Case Report

The Odontogenic Keratocyst considered potentially aggressive and of high recurrence located between 30 and 60%, with clinical and radiographic characteristics not clearly defined. It occurs at any stage of life. The 70 to 80% of the cases are located in the jaw, commonly in the area of the lower third molar and mandibular angle from where they progress towards the branch and the body. The lesions are long latent, often asymptomatic and can reach remarkable dimensions without significant deformation of the jaw bones. They are often found during the routine radiographic examination.
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Castleman’s Disease: a Diagnosis to Eliminate in Cases of Cervical Lymphadenopathy

Castleman’s disease is due to a lymphoproliferative disorder by the polyclonal proliferation of B cells inside lymphoid organ.Two types exist: the localized form which is usually benign and multicentric form which is more severe. The main risk is the development of lymphoma. Our aim is to report a case of a 18 years old man patient. Her medical history was unremarkable. She presented with a localized form on the right side of neck lymph node. After the ablation of the nodes,none relapse was noticed.
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Adrenal Incidentalomas - From Diagnosis to Follow-Up: Endocrine and Imaging Features at Diagnosis and Over Time

Adrenal incidentalomas (AIs) are frequent and although most of them are asymptomatic and benign, some do need treatment. The AIs follow-up has to be as sharp as to avoid missing pathology and to avoid harm and anxiety induced by the follow-up itself. It is, thus, a delicate medical condition for endocrinologists worldwide.
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Pulmonary Nocardiosis: A Rare Diagnosis in an Intensive Care Unit

Nocardiosis is an acute, subacute, or chronic bacterial infection that is typically acquired through inhalation and usually presents with pulmonary, central nervous system, and cutaneous manifestations. In critically ill patients, Nocardiosis has an unusually high morbidity and mortality.
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Liquid-Based Cytology Compared to Conventional Cytology for Diagnosis of Cervical Intraepithelial Neoplasia: A Single-Center Experience

Cervical carcinoma is the fourth most common gynecologic cancer. Screening assays that include the conventional cytology (CC) have a sensitivity and specificity far from optimal; however, liquid-based cytology (LBC) may overcome some limitations. The objective is to compare the screening accuracy of LBC and CC in individuals suspected of having precancerous lesions. A prospective, single center study, recruited individuals from a tertiary-level center. In all participants, CC and LBC were performed. Clinical, cytologic and histopathologic results were collected. Bethesda System was used and agreement of two of three cytopathologists was necessary to assign a positive or negative result. Cervical biopsy was performed in participants with abnormal findings.
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Editorial Board Members Related to Diagnosis

Adolfo Godoy Pinto

Professor
Veterinary Medicine and Animal Science
University of Chile
Chile

Mamatha Ballal

Professor
Melaka Manipal Medical College
Manipal University
India

James Tao

Associate Professor
Department of Neurology
The University of Chicago
United States

WANG CHI CHIU

Professor
Department of Obstetrics & Gynecology
The Chinese University of Hong Kong
Hong Kong

Xiaoqing Guo

Division of Genetic and Molecular Toxicology
National Center for Toxicological Research (NCTR)
USA

Monique Mancuso

Researcher
Coastal Marine Environment Institute (IAMC)
National Research Council (CNR)
Italy

Andrzej Wernicki

Professor
Faculty of Veterinary Medicine
University of Life Sciences
Poland

JON B. SUZUKI

Professor
Department of Periodontology & Oral Implantolog
Temple University
United States

GAVIN PAUL SACKS

Associate Professor
Department of Obstetrics & Gynecology
University of New South Wales
Australia

Jerry R. Roberson

Associate Professor
Theriogenology/Large Animal Medicine
Ross University School of Veterinary Medicine
West Indies
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