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Articles Related to Diagnosis

Castleman’s Disease: a Diagnosis to Eliminate in Cases of Cervical Lymphadenopathy

Castleman’s disease is due to a lymphoproliferative disorder by the polyclonal proliferation of B cells inside lymphoid organ.Two types exist: the localized form which is usually benign and multicentric form which is more severe. The main risk is the development of lymphoma. Our aim is to report a case of a 18 years old man patient. Her medical history was unremarkable. She presented with a localized form on the right side of neck lymph node. After the ablation of the nodes,none relapse was noticed.
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Adrenal Incidentalomas - From Diagnosis to Follow-Up: Endocrine and Imaging Features at Diagnosis and Over Time

Adrenal incidentalomas (AIs) are frequent and although most of them are asymptomatic and benign, some do need treatment. The AIs follow-up has to be as sharp as to avoid missing pathology and to avoid harm and anxiety induced by the follow-up itself. It is, thus, a delicate medical condition for endocrinologists worldwide.
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Pulmonary Nocardiosis: A Rare Diagnosis in an Intensive Care Unit

Nocardiosis is an acute, subacute, or chronic bacterial infection that is typically acquired through inhalation and usually presents with pulmonary, central nervous system, and cutaneous manifestations. In critically ill patients, Nocardiosis has an unusually high morbidity and mortality.
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Liquid-Based Cytology Compared to Conventional Cytology for Diagnosis of Cervical Intraepithelial Neoplasia: A Single-Center Experience

Cervical carcinoma is the fourth most common gynecologic cancer. Screening assays that include the conventional cytology (CC) have a sensitivity and specificity far from optimal; however, liquid-based cytology (LBC) may overcome some limitations. The objective is to compare the screening accuracy of LBC and CC in individuals suspected of having precancerous lesions. A prospective, single center study, recruited individuals from a tertiary-level center. In all participants, CC and LBC were performed. Clinical, cytologic and histopathologic results were collected. Bethesda System was used and agreement of two of three cytopathologists was necessary to assign a positive or negative result. Cervical biopsy was performed in participants with abnormal findings.
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New Insight for Early Diagnosis of Neonatal Sepsis

Mean platelet volume MPV that is included in CBC, will be larger with platelet destruction problems as in Neonatal sepsis NS or when the body is producing increased numbers of platelets. Also, NS is associated with increased production of reactive oxygen species that will lead to consumption of specific antioxidant molecules like uric acid. The aim of the work: to determine the role of MPV and uric acid levels in the early diagnosis of NS.
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Dawn of the Biofilm Disease: Highlights about Biofilm in Bone and Joint & Prosthetic Joint Infections Pathogenesis, Diagnosis and Treatment

I present some key considerations of the biofilm disease as part of two complex pathologies such as bone and joint infections and prosthetic joint infections, taking into account the bacterial pathogenic factors to understand the particular nature of these infections, and to achieve an accurate diagnosis and management beyond the antimicrobial therapy. I mention some personal experience of many years in the medical microbiology laboratory and next to the patient’s bed.
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Cell Culture, Cytopathic Effect and Immunofluorescence Diagnosis of Viral Infection

Viruses are obligate intracellular parasites that require living cells in order to replicate. Cell culture for propagation and identification of viruses is an important component of the clinical virology laboratory. In general, diagnostic tests can be grouped into three categories: direct detection, virus isolation and serology. Direct examination methods can usually give a result either within the same or the next day. Immunofluorescence is widely used for the rapid diagnosis of virus infections by detection of virus antigen in clinical specimens and detection of virus-specific antibodies.
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Usefulness of a Pressure Wire for the Diagnosis of Vasospastic Angina during a Spasm Provocation Test

Spasm provocation tests (SPTs) using a pressure wire and compared the results with those from patients who underwent the same test without a pressure wire.
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Detection of Anti-Trypanosoma Cruzi Antibodies among Donors at A Blood Bank from Southern Mexico, Using an Iron Superoxide Dismutase Excreted (Fe-Sode) as Antigen

Trypanosoma cruzi, the causal agent of Chagas disease in humans, is a widely spread protozoan in Latin America. Chronically infected people are asymptomatic during an indeterminate stage but can represent a significant risk of transmission due to blood donations and organ transplants. Blood transfusion is recognized as the second most important path for transmitting of Chagas disease
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The Importance of Brain MRI in the Diagnosis of Marchiafava-Bignami Disease

Marchiafava-Bignami disease (MBD) is a neurological disorder that has been found to be associated with chronic alcoholism and malnutrition. We report a 45 year old man, chronic alcoholic that developed discouragement for activities involving daily living, changes in retrograde memory in addition to mutism and gait instability. Brain MRI showed central atrophy of the corpus callosum(CC), hypointensity(necrosis) and ventricular dilation(white matter and subcortical region involvement).
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A Case of Solitary Fibrous Tumor of the Mesorectum: Usefulness of Immunohistochemical Staining for a Differential Diagnosis from a Gastrointestinal Stromal Tumor

Extrapleural solitary fibrous tumors (SFT) and gastrointestinal stromal tumors (GISTs) are similar morphologically and on imaging studies. We report a case of a patient with a giant pelvic tumor, which was difficult to be diagnosed. A 71-year-old male presented to our hospital with a complaint of urinary retention. A radiological examination showed a giant pelvic tumor mass, which ventrally compressed the urinary bladder and rectum, and was supplied by vascular flow from the right internal iliac artery. The resected specimen was 15 × 10 cm, elastic soft, and solid pale yellow in color. Because the tumor was histologically composed of spindle-shaped cells and was CD34 positive, cytokeratin negative, epithelial membrane antigens negative and KIT negative, we first thought the tumor was a KIT-negative GIST.
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Predictors of Delayed Diagnosis and Evolution in Sub-Saharan Immigrants with HIV Infection in a Hospital in Madrid (2004–2013)

The aim of this study was to analyze the delayed diagnosis and evolution of HIV infection in predominantly sub-Saharan immigrants compared to other patients in a hospital in Madrid between 2004 and 2013. We retrospectively analyzed new HIV diagnoses. Late presentation or advanced disease were considered the presence of CD4 lymphocyte counts less than 350 or 200 cells/µl at diagnosis, respectively, or an AIDS-defining disease regardless of the CD4 count. Patients were compared according to their origin and sex.
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Diagnostic Approaches towards Camelpox Disease

Camelpox is routinely diagnosed based on clinical signs, pathological findings and cellular and molecular assays.
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Case Report of Severe Preeclampsia and Associated Postpartum Complications

Preeclampsia is clinically defined by hypertension and proteinuria, with or without pathologic edema that occurs after 20 weeks’ gestation, but can also present up to 4-6 weeks post-partum. Worldwide, incidence of preeclampsia is 5-14 percent of all pregnancies, while severe preeclampsia can develop to about 25 percent of all cases of preeclampsia.
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Fibromatosis Colli, a Rare Cause of Neck Mass in Infants: A Case Report

Fibromatosis colli is a benign fibrous mass developed from the sternocleidomastoid muscle. The exact etiologies are unknown. It seems that it is due to birth trauma. Ultrasound is the diagnostic tool of choice. The treatment is based on physiotherapy.
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Editorial Board Members Related to Diagnosis

Nikolić Dragan M

Faculty of Medicine
University of Belgrade
Serbia

Dimitrios Kanakis

Associate Professor
Department of Pathology
University of Nicosia Medical School
Cyprus

Shereen Mohamed Mohamed Olama

Professor
Department of Rheumatology and Rehabilitation
Faculty of Medicine
Mansoura University
Egypt

Nallasivam Palanisamy

Associate Professor
Michigan Center for Translational Pathology
University of Michigan
United States

PAUL G HORGAN

Professor
Department of Surgery
University of Glasgow
United Kingdom

GAVIN PAUL SACKS

Associate Professor
Department of Obstetrics & Gynecology
University of New South Wales
Australia

Lin Feng

Associate Professor
Bioinformatics Research Centre
Nanyang Technological University
Singapore

Zhonghua Sun

Associate Professor
Department of Imaging and Applied Physics
Curtin University
Australia

Mohamed Abdo Rizk

Professor
Department of Internal Medicine and Infectious Diseases
Mansoura University
Egypt

IOANNIS D. BASSUKAS

Professor
Dermatology
School of Medicine
University of Ioannina
Greece
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