Articles Related to Drug Delivery
Review on Transdermal Drug Delivery System-Focus on Innovative 2 Transdermal Dosage Forms
The transdermal drug delivery system is technique that provides drug through the intact skin. Skin penetration enhancement techniques have been developed to increase the bioavailability of drug substance. These review describes various transdermal patches available in market, types of patches, basic components, polymer used in formulation. The novel drug delivery method do well and complete with those already on the market the main problem that requires consideration include device design and safety, efficacy, ease of handling and economical. Transdermal drug delivery system represent the most attractive method among these because of its low rejection rate, magnificent, ease of administration and better convenience and compliance with patient. This review article provide an overview of transdermal drug delivery system contains various innovative dosage forms. In comparison transdermal patch are effective due to its easy to apply and non-invasive.
Mucoadhesive Drug Delivery Systems-An Overview
The term mucoadhesion can be defined as a phenomenon of interfacial molecular attractive forces in the layer of surface of a biological
membrane and the natural or synthetic polymer, which allows the polymer to the adhere the surface of that membrane for an extended as well
prolonged period of time. Since the last four decades, the conception of mucoadhesion has achieved a important precious interest in the
various fields of pharmaceutics
Review on Recent Approaches in Transdermal Drug Delivery System
Transdermal drug delivery system has become a proven technology that offer significant clinical benefit over the dosage forms. Drugs with very short half-life, narrow therapeutic window, and poor bioavailability-transdermal drug system are convenient. Skin serves as site of drug application for local as well as systemic effects. There are wide varieties of drugs for which topical or transdermal is viable options
An Introduction to the Approaches of Novel Drug Delivery Systems for Acquired Immune Deficiency Syndrome (AIDS)
The currently available anti HIV agents have several drawbacks such as short half life, low bioavailability, poor CNS penetration and
retention, hepatic first pass metabolism, undesirable side effects and frequent dosing regimen.
A New Bi-Functional Derivative of Polyethylene Glycol as Molecular Carrier for Eugenol and Ibuprofen
Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecular carrier of drugs and the release kinetics of the two bioactive molecules was studied in vitro in buffer solution at pH 7.4, in simulated gastric fluid and in mouse plasma.
Evaluation of Luffa Aegyptica Mill Powder: A Novel Superdisintegrant in Delayed Release Tablets
The current research in the field of drug delivery by which pulsatile release can be achieved has been intensified. The objective of the present study was to evaluate Luffa aegyptica mill powder as a novel superdisintegrant in the development of pulsatile drug delivery system (PDDS).
Nanotechnology Approaches for Antiretroviral Drugs Delivery
The development of effective drug delivery approaches for the treatment of AIDS and HIV infection is a global challenge. The advent
of multidrug, highly active antiretroviral therapy (HAART), have increased the life span of HIV-infected patients.
Review on Transdermal Drug Delivery Systems
Recently, transdermal drug delivery system (TDDS) has become a more and more important approach to administering drugs. Based on its advantages, which are not achievable by other modes of administration, many researchers are dedicated to the study of it, and have made great progress. Although the skin offers a painless interface for systemic drug delivery, it also presents limitations which are mainly caused by the stratum corneum.
Wet Granulation to Overcome Liquisolid Technique Issues of Poor Flowability and Compactibility: A Study to Enhance Glibenclamide Dissolution
The aim of this study is to apply wet granulation on liquisolid powders to overcome issues of poor powder flowability and compressibility especially with using high viscosity liquid vehicles. Different liquisolid formulations were made using three excipients where the effect of each excipient used in the dissolution of the model hydrophobic drug (Glibenclamide) was evaluated. The Glibenclamide tablets were formulated using PEG 400, Synperonic PE/L44 and Cremophor ELP, at a 10 %w/w in liquid vehicle drug concentration. The carrier (Avicel®PH102) was used followed by colloidal silicon dioxide (coating material) that converted the wet mixture into dry powder. Potato starch, 5%w/w, as a disintegrant was mixed with the mixture manually for 10 minutes and was finalized by adding 0.75% of magnesium stearate as a lubricant.
Perspectives and Potential Applications of Ruthenium-Based Nanocarriers for Cancer Therapy
Cancer is a highly heterogeneous disease characterised by continuous uncontrolled growth and expansion of abnormal cells. In general, in tumor cells the signalling pathways regulating cellular processes, as cell growth and division and cell to cellcommunication result strongly altered.
Topical Delivery System for Phytochemicals: Capsaicin and Capsicum Tincture
Capsaicin, an active ingredient of Capsicum fruit, is currently undergoing “revival” in the clinical management of pain. However, the choice of its formulation is rather limited to the use of “old-fashioned” tinctures and recently the patches. In an attempt to improve the therapeutic outcome and develop its skin-friendly formulation, we prepared the vesicle-based drug delivery system with capsaicin.
Biocompatible Polymers and Processing Techniques in Drug Delivery and Tissue Engineering
In recent years many progress has been achieved in the biomedical and biopharmaceutical fields particularly in drug delivery and regenerative medicine. This has been possible thanks to the increased expertise in polymers chemistry as well as the advent of innovative techniques of materials manipulation that have lead to the production of new “smart” polymeric devices with peculiar propertiesable to selectively reach almost all areas of the human body, in the case of drug delivery systems, or to reduce the chemical-physical gap between human tissues and synthetic devices, in the case of tissue engineering.
Polymeric Nano-Fibers and Modified Nano-Fibers Assembly in 3D Network for Different Potential Applications
Polymeric nano-fiber based materials and their application is one of the research areas in materials science and nanotechnology. Nano-fibrous materials are receiving extensive research interest for applications in diverse fields as biosensors, optical and chemical sensors, stimuli-responsive or "smart" materials, bioreactors, drug delivery carriers, etc.
Editorial Board Members Related to Drug Delivery
Fatemeh Baghbani
Faculty of Biomedical Engineering
Amirkabir University of Technology
Iran
Amirkabir University of Technology
Iran
Daniela Iannazzo
University Researcher
Department of Electronic Engineering, Industrial Chemistry and Engineering
University of Messina
Italy
Department of Electronic Engineering, Industrial Chemistry and Engineering
University of Messina
Italy
Ibrahim El-Sherbiny
Associate Professor
Department of Nanomaterials Science
University of Science and Technology
Egypt
Department of Nanomaterials Science
University of Science and Technology
Egypt
Diego Andrés Chiappetta
Associate Professor
Department of Pharmaceutical Technology
University of Buenos Aires
Argentina
Department of Pharmaceutical Technology
University of Buenos Aires
Argentina
Lili Chen
Associate Professor
Department of Radiation Oncology
Fox Chase Cancer Center
United States
Department of Radiation Oncology
Fox Chase Cancer Center
United States
XU-FENG HUANG
Professor
School of Health Sciences
University of Wollongong
Australia
School of Health Sciences
University of Wollongong
Australia
Ana Rita Ramalho Figueiras
Faculty of Pharmacy
University of Coimbra
Portugal
University of Coimbra
Portugal
Zhenghong Wu
Professor
Department of Pharmaceutics
China Pharmaceutical University
China
Department of Pharmaceutics
China Pharmaceutical University
China
Nils Ole Schmidt
Neurosurgeon
Department of Neurosurgery
University Medical Center Hamburg-Eppendorf
Germany
Department of Neurosurgery
University Medical Center Hamburg-Eppendorf
Germany
Neama Ahmed Sobhy Ahmed Reiad
Faculty of Engineering
Department of Chemical Engineering
Cairo University
Egypt
Department of Chemical Engineering
Cairo University
Egypt