Articles Related to ECG
Evaluating the Effect of Oprelvekin on Cardiac Repolarization in Subjects with Chemotherapy-Induced Thrombocytopenia: An Observational Chart Review of a Phase 2 Clinical Trial in Laredo, Texas
This study tested for the cardiac effects of Oprelvekin, recombinant human interleukin-11, a thrombopoietic growth factor, in patients afflicted with chemotherapy-induced thrombocytopenia (platelet count<50,000 cells/ul). Chart-reviews of patients fulfilling the inclusion criteria of: 18-75 yrs of age, non-myeloid malignancy, with adequate hematologic, hepatic and renal parameters and normal electrocardiograms that were enrolled in this phase 2 trial were analyzed. Patients of child-bearing potential agreed to be on a reliable form of birth control for the duration of the study. Results on 4 patients suggest that Oprelvekin does not cause atrial nor ventricular arrhythmia, a rare severe cardiac side effect, in treating patients with chemotherapy-induced thrombocytopenia.
Spontaneous Coronary Artery Dissection: Efficient Clinical Outcome through Percutaneous Coronary Intervention
Spontaneous coronary artery dissection (SCAD) is a rare myocardial ischemic disease that threatens patients’ life. Various risk factors are associated with SCAD, such as smoking, severe hypertension and psychological reasons. Considering the formation of dissection, SCAD can be divided into intimal tear type or intraluminal hemorrhage type.
There is a frequent association between renal insufficiency and patients with cardiovascular disease, suggesting a common pathogenic mechanism.
Fatal arrhythmia is the leading cause of mortality in chronic haemodialysis patients. Long QT syndrome is responsible for polymorphic ventricular tachycardia known as Torsade de Pointes. Classically, long QT syndromes were divided into congenital and acquired; however ‘silent’ variants, in which patients remain asymptomatic until exposed to a drug or electrolyte disturbance precipitating the arrhythmia, have now been recognized.
Postoperative atrial fibrillation (POAF) is a common and dangerous complication following cardiac surgery.
Could Non-Linear Heart Rate Variability Analysis of Short RR Intervals Series Give Clinically Valuable Information in Heart Disease?
New analytic methods based on nonlinear system theory have been developed to characterize the nonlinear features in HR dynamics. It is known from long time series (24h ECG recordings) that patients with chronic heart failure or stable coronary heart disease have altered fractal organization in heartbeat dynamics. During such long-time series, many confounding could limit the assessment of autonomic functions.
Statistics across industrialised societies show that occupational stress results in social and financial costs for individuals, organisations, and economies. Occupational stress is prevalent in many different forms, for example, work intensification, dissatisfaction with current work schedules, feelings of job insecurity, more work being done at odd hours, the spread of new information and communication technologies, and long hours becoming more common.
An Ultra-High Pressure Liquid Chromatography Time-of-Flight Mass Spectrometry (UHPLC-TOF-MS) method for quantitative analysis of 30 drugs in whole blood was developed and validated. The method was used for screening and quantification of common drugs and drugs of abuse in whole blood received from autopsy cases and living persons.