Articles Related to EMA

Sugarcane is a vital cash crop grown in about 200 tropical and sub-tropical countries around the world. Due to its high rates of occupational diseases, accidents, and fatalities the agro industry is regarded as one of the most hazardous industries despite being one of the essential sectors globally regarding food supply and workforce. Most of the world's cane sugar crop is produced In Low- and Middle-Income Countries (LMIC), such as Sudan, where agriculture and farming are still the main sources of income and managing occupational health and safety is challenging

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: Ammonia is corrosive and exposure will result in a chemical-type burn. It is highly hygroscopic and readily transforms the moist areas of the body such as eyes, nose, throat, and moist skin areas. It is a highly toxic irritant gas, and its toxicity usually occurs from occupational exposure, most are unintentional toxicity. It causes tissue damage via exothermic reaction with body tissues causing liquefactive necrosis. Release of ammonia has potentially for harmful effects on workers and the public. Although there have been incidents of exposure to harmful concentrations of ammonia in the world there have been few fatal accidents.Presentation depends on the level and duration of exposure. Management is supportive and its antidote is not available yet

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The optimal design of heliostat field in solar power generation device is studied Heliostat field generates high temperature by focusing the sunlight reflected from the mirror surface, thus pushing the turbine to generate electricity. In order to improve the efficiency of power generation, this paper optimizes the parameters of heliostat field, establishes a singleobjective optimization model, and uses mixed strategy whale optimization algorithm to solve it. Through geometric optical analysis and ray tracing model, the optical efficiency of heliostat field and the annual average output thermal power per mirror area are calculated. Finally, through the discussion and analysis of the model, the optimization design method is evaluated.

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Anthropometric data of Nigerian male and female agro equipment operators was determined as the operators were in a standing position. Field workers that facilitated the anthropometric measurements were trained and grouped into three groups – namely, coordinating supervisors, data collating officers and data collecting officers. The anthropometric data were collated from various individuals within the ages of (18 to 60) years from three states in each of the six geopolitical zones in Nigeria

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Eczema herpeticum (EH) is a skin infection caused by the herpes simplex virus (HSV) that occurs in individuals with atopic dermatitis. It is characterized by the sudden appearance of vesicles and erosions with crusts over areas affected by eczema. EH can range from mild and self-limiting in healthy adults to life-threatening in children, infants, and immunocompromised patients. Early treatment with antiviral therapy is crucial in preventing complications and mortality. EH is primarily caused by a superinfection of HSV, usually HSV-1, in individuals with atopic dermatitis. Reactivation of HSV is more common than primary infection. Patients with atopic dermatitis are more susceptible to skin infections due to impaired skin barrier function and immune dysregulation. Disseminated cutaneous HSV infection can also occur in individuals with other forms of dermatitis, known as Kaposi varicelliform eruption (KVE)

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: Obesity is a global epidemic with serious consequences for countries. Objective: This work aims to systematically review the available evidence on the relationship between basal metabolism (BM), body composition, and physical activity (PA) with central obesity. Methodology: The search strategy was carried out using Web of Science, PubMed, Google Scholar, and SciELO following the PRISMA guidelines. The STROBE checklist and the Jadad scale were also used for quality assessment.

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Using kinetic differential equations and the Runge-Kutt algorithm, an analysis of the pathological processes occurring in the course of Alzherimer’s disease was carried out. Thanks to the appropriately selected kinetic equations, the presented model allows to explain the time course of the growth of pathological proteins: beta-amyloid and tau protein and the related loss of nerve cells. The model is based on previous experimental knowledge of Alzherimer’s diseas and is in good agreement with the experimental data.

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This study is an attempt to emphasize the prevalence of severe anemia in pediatric age group and characterize different clinical and Hematological findings among them. Anemia is a major global health problem, especially in developing countries like India, despite the fact that this problem is largely preventable & easily treatable. It leads to morbidity and mortality in children and establish a public health problem of substantial importance.

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The purpose of this study was to clarify the response of Ningxiang pig against pathogenic enterotoxigenic Escherichia coli (ETEC) during the weaning period. Sixteen weaned Ningxiang pigs, were selected from one litter at 28 days and randomly allocated into two groups, with or without oral administration of ETEC (109 colony forming units/piglet/d) for two consecutive days. Blood and intestinal samples were collected after sacrifice to investigate the influence for systemic and gastrointestinal tract influences

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n recent years’ nanostructure materials (NSMs) have been of great interest as catalysts and other applications because of their unique textural and structural characteristics. Out of various biomaterials employed for NPs synthesis, plant extracts have attracted much attention due to their effectiveness, availability, and green characteristics. Due to the range of chemical constituents, currently, the incorporation of the Aloe chemical constituents into other substances makes the biosynthesis of NPs which are very necessary for the formation and applications ofAloe-based NPs

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Dental practice involves a risk of exposure to microorganisms causing many infectious diseases. The risk of contamination starts at the beginning of the prosthetic workflow through impressions. Various chemical disinfection protocols for dental impressions are reported in the literature.

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Diabetic macular edema (DME) has become one of the most potential complications that results in loss of vision in patients with diabetic retinopathy. Treatment outcomes that have been predicted directly with advent of machine learning (ML) methods after the initial anti-vascular endothelial growth factor (anti-VEGF) injection, has become extremely vital in the management of DME. Purpose: The aim of this study is to analyze the efficiency of the ML regression models which were developed and validated to predict the possible post-injection central subfield thickness (CST) value and distant vision best corrected visual acuity (DV BCVA) in eyes with DME before the anti-VEGF injection is administered at either treatment initiation or during treatment monitoring. Methods: This retrospective study was conducted in Medical Research Foundation, Chennai, India from January 2010 to December 2020. The model development emphasized on an ensemble ML system consisting of four ML models that were developed and trained independently using the clinical parameters to predict the post injection CST value. The dataset consisting of 906 patients with total of 1874 samples [Optical coherence tomography (OCT) images and clinical parameters] were divided into trained and test set, and the model was validated on test dataset. The predicted CST values was then compared against the respective sample’s post injection actual CST value. The comparative results were measured in terms of Correlation Coefficient and Mean Absolute Relative Error (MARE). Results: On evaluation, we found that Support Vector Regression (SVR) with linear kernel performed best among the other models with four different scenarios in term of both CST and DVBCVA prediction with correlation coefficient of 0.65, 0.73, 0.75, 0.85 and 0.83, 0.87, 0.89 and 0.92 respectively.

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Bloodstream infections (BSI) are one of severe infectious complications faced by hematopoietic stem cell transplantation (HSCT) patients. BSI increases significantly the morbidity and mortality of HSCT patients. Gram-positive bacteria occurred more frequency than gram-negative bacteria over past decades, but rates of gram-negative bloodstream infections have recently increased again. Antibacterial prophylaxis could be justified in HSCT, infections caused by resistant pathogens increased mortality. New antibiotics such as omadacycline, meropenem/vaborbactam, eravacycline, ceftobiprole, tedizolid, dalbavancin, cefiderocol hold promise for the treatment of highly resistant pathogens.

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Osteoarthritis is an inflammatory-degenerative joint disease that affects the osteochondral unit with the concomitant intervention of the immune system; this causes pain and progressive functional limitation. With a varied and complex etiopathogenesis, Osteoarthritis has a subtle outcome and an inexorable evolution towards joint deformity. The therapeutic approach makes use of non-pharmacological and pharmacological aids. Pharmacological therapy consists of symptomatic drugs that act on acute and especially chronic pain, in an attempt to decrease the incidence of any structural damage to the cartilage and subchondral bone. If the anti-resorptive drugs cure the subchondral-epiphyseal osteometabolic pathology, the interventions on the cartilage have not produced important and well evaluable results, even after prolonged therapies. This contribution analyzes the profile of Clodronate, used for the treatment of subchondral bone edema in Osteoarthritis, regarding its potential protective effects in cartilage, like DMOADs.

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