Articles Related to EOC
Relation between Osteocalcin and Metabolic Profils in Overweight Men: Comparison of Aerobic and Resistance Trainings
Objectives: Recent studies have shown that exercise by affecting bones causes the release of hormones that are effective in
regulating blood glucose, lipid profile and preventing vascular calcification. The present study aims to Comparison effect
of aerobic and resistance exercises on Osteocalcin and Metabolic Profils in Overweight men.
Methods: total of 33 overweight healthy men (BMI 29 = 67.96 ± 0.96 and age 33.2 ± 2.23) were randomly assigned into
three groups: control (n = 11), aerobic (n = 11) and resistance exercise (n = 11) groups. The training program was conducted for 8 weeks, 3 sessions per week for the training groups. Body compositions parameters (weight, body fat percent,
BMI) were analyzed, osteocalcin and blood biochemical parameters were assessed from fasting blood samples before and
after 8-week exercise programme.
Results: Body fat, BMI and body weight reduction following exercise (P<0/05), significantly increased serum Osteocalcin
(P<0/05, baseline vs Post exercise) and blood biochemical parameters significantly changes (P < 0/05). Increase in osteocalcin had a negative correlation with changes in body composition, as well as HOMA-IR and HDL, LDL not significantly
(all P > 0/05).
Conclusion: Aerobic and Resistance exercise cause to changes in body weight, body fat, BMI, as well as the increase level of
osteocalcin and improvement of glucose metabolism and lipid profiles. However, the difference between the two training
groups was not statistically significant.
Clodronate : A Potential DMOAD in Osteoarthtitis
Osteoarthritis is an inflammatory-degenerative joint disease that affects the osteochondral unit with the concomitant intervention of the immune system; this causes pain and progressive functional limitation. With a varied and complex etiopathogenesis, Osteoarthritis has a subtle outcome and an inexorable evolution towards joint deformity. The therapeutic
approach makes use of non-pharmacological and pharmacological aids. Pharmacological therapy consists of symptomatic
drugs that act on acute and especially chronic pain, in an attempt to decrease the incidence of any structural damage to the
cartilage and subchondral bone. If the anti-resorptive drugs cure the subchondral-epiphyseal osteometabolic pathology,
the interventions on the cartilage have not produced important and well evaluable results, even after prolonged therapies.
This contribution analyzes the profile of Clodronate, used for the treatment of subchondral bone edema in Osteoarthritis,
regarding its potential protective effects in cartilage, like DMOADs.
An Adjuvant Approach to Alleviate Reoccurring or Treatment Resistant Symptoms of IBD in Companion Animals
Inflammatory bowel disease (IBD) is a common yet distressing condition afflicting tissues of the gastrointestinal (GI) tract in
companion animals; symptoms include vomiting, diarrhoea, loss of appetite and weight loss. Pathogenesis of IBD may link to both
diet and parasitic or bacterial infections of the gut. Although current treatments may provide some relief to the animal, unfortunately
recurrent flaring of symptoms is not uncommon. Therapeutic interventions available to the veterinarian include those that focus on
treating any underlying infection and or a change in diet, both employed with the aim of reducing inflammation.
Tracheobronchopathia Osteochondroplastica: A Case Report
Tracheobronchopathia osteochondroplastica (TOCP) is a rare disease defined by the presence of osteocartilaginous foci
in the submucosa, without direct connection to the cartilage structures of the respiratory tree. The disease is usually located in the trachea, sometimes in the bronchi and more rarely in the larynx.
Former Effective Immunotherapy without Adverse Events of Inoperable Epithelial Ovarian Cancers and a Prospect for the Immune Prophylaxis
Current cancer treatments by immune checkpoint blockades are limited due to severe adverse events caused by alteration of the immune system required for homeostasis of normal tissues. Common cancer chemotherapy alters the quality of patients’ lives. Platinum-based treatment can lead to severe neurotoxicity with chronic debilitation. Additionally, survival of patients with epithelial ovarian cancers (EOCs) has remained poor despite extensive cytoreductive surgery, high dose chemotherapy, checkpoint blockades and immunotherapies effective in some other types of cancer. The pathobiology of EOC cancer stem cells (CSCs) is not well understood. Observations demonstrate that EOCs exhibit in vivo two distinct CSC types - perivascular diploid CSCs dividing asymmetrically with the help of the host suicidal CD8+ T cells, and haploid CSCs at the cancer abdominal surface originating from meiosis I cytokinesis of bulk surface cancer cells. The perivascular CSCs contribute to the cancer cell bulk and, via left ovary venous blood, can cause EOC liver metastases. Haploid CSCs released from the bulk cancer surface cause the common pelvic and abdominal EOC spread. Former elimination of the host antibodies blocking T cell effectors by intermittent doses of cyclophosphamide exhibiting significant immunomodulatory anticancer effects, facilitation of the immune system reactivity against alloantigens of cancer cells by blood transfusions, and augmentation of anticancer immunity by bacterial toxins, resulted during the subsequent treatment-free period into rejection of inoperable EOCs without any adverse events during the treatnment. To help prevent cancer relapses, patients treated for advanced primary epithelial cancers should be considered as candidates for continuously stimulating immune anticancer activity by treatments such as daily metformin and weekly lentinan consumptions.
A Study of Immune Response in Nile Tilapia (Oreochromis niloticus) Fed Levamisole Incorporated Diet
This study was undertaken to evaluate the influence of levamisole on the immune enhancement of Nile tilapia (Oreochromis niloticus) against potential bacterial pathogens, Fish with weight of 98±5 g were randomly distributed into seven groups each at a rate of 20 fish per 300-L aquarium and fed on a diet containing 0.0, 250, 500, 750, 1000, 1250 or 1500 mg levamisole/kg diet for eight weeks.
ESBL-Producing E. Coli in a Patient on Automated Peritoneal Dialysis
Peritoneal Dialysis (PD) is one of the 3 well-established modalities of renal replacement therapy used in patients with renal failure. Despite its significant role as a successful method of renal replacement therapy, PD is highly associated with peritonitis and catheter-related infections.
Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites
Ovarian cancer constitutes the second most common gynecological cancer with a five-year survival rate of 40%. Among the various histotypes associated with hereditary ovarian cancer, high-grade serous epithelial ovarian carcinoma (HGSEOC) is the most predominant and women with inherited mutations in BRCA1 have a lifetime risk of 40-60%. HGSEOC is a challenge for clinical oncologists, due to late presentation of patient, diagnosis and high rate of relapse. Ovarian tumors have a wide range of clinical presentations including development of ascites as a result of deregulated endothelial function thereby causing increased vascular permeability of peritoneal vessels.
Review on Transdermal Drug Delivery Systems
Recently, transdermal drug delivery system (TDDS) has become a more and more important approach to administering drugs. Based on its advantages, which are not achievable by other modes of administration, many researchers are dedicated to the study of it, and have made great progress. Although the skin offers a painless interface for systemic drug delivery, it also presents limitations which are mainly caused by the stratum corneum.
Feasibility Analysis of Autogenous Tooth-based Bone Graft Material after Guided Bone Regeneration Technique
We set out to determine the possibility of radiographically evaluating the degree of marginal bone loss in humans after functional loading of implants at sites of guided bone regeneration (GBR) with autogenous tooth-based bone graft (ATBBG) material (AutoBT®, Korea Tooth Bank, Seoul, Korea).
Juvenile Ossifying Fibroma - WHO Type
Juvenile ossifying fibroma is an uncommon clinical entity, its aggressive local behaviour and high recurrence rate mean that it is important
to make an early diagnosis, apply the appropriate treatment and, especially, follow the patient up over the long term. In the
current article we report a case of juvenile ossifying fibroma-WHO type in 12yr old patient which was clinical and histopathologically
challenging as it was asymptomatic and at an unusual location.
The Updated International Veterinary Anatomical and Embryological Nomenclatures
The international nomenclature of the anatomical, histological and embryological terms is known as Nomina Anatomica Veterinaria (N.A.V.), Nomina Histologica Veterinaria (N.H.V.) and Nomina Embryologica Veterinaria (N.E.V.).
Editorial Board Members Related to EOC
Russell D Frew
Professor
University of Otago
Department of Chemistry
New Zealand
University of Otago
Department of Chemistry
New Zealand
JACQUES MARESCAUX
Professor
Department of Surgery
Research Institute Against Digestive Cancer
France
Department of Surgery
Research Institute Against Digestive Cancer
France
Madhuresh Kumar Sethi
Researcher
Research and Development
Mylan Laboratories Limited
India
Research and Development
Mylan Laboratories Limited
India
Saeid Abroun
Associate Professor
School of Medicine
Tarbiat Modares University
Iran
School of Medicine
Tarbiat Modares University
Iran
Mohamed M. El Alfy
Associate Professor of Hydrogeology
Prince Sultan Institute For Environment
Water and Desert Research
King Saud University
Saudi Arabia
Prince Sultan Institute For Environment
Water and Desert Research
King Saud University
Saudi Arabia
Qingsong Ye
Associate Professor
Department of Orthodontics
James Cook University
Australia
Department of Orthodontics
James Cook University
Australia
Adolfo Antonio Gutiérrez
Professor
National University of Tucumán
School of Natural Sciences and IML
Argentina
National University of Tucumán
School of Natural Sciences and IML
Argentina