Articles Related to ETs
Comparison of Physicochemical and Binding Properties of Novicel™ Microcrystalline Cellulose and Avicel® PH 101 in Direct Compression of Ascorbic Acid Tablets
Microcrystalline cellulose (MCC) is a key excipient in formulation and production of pharmaceutical solid dosage forms such
as tablets. In this study, the microcrystalline cellulose (Novicel™) obtained from sugarcane bagasse (a waste material from
sugarcane factories) was compared with Avicel PH 101 (a commercially available MCC) for its physicochemical characteristics
and potential as a dry binder in direct compression of ascorbic acid tablets.
Bioequivalence Studies of Two Formulations of Rivaroxaban 10 Mg Coated Tablets under Fasting Conditions and 20 Mg Coated Tablets Under Fed and Fast Conditions And its Pharmacokinetic Comparison In Healthy Subjects
Justificative: This trial was conducted in order to register a new generic product of Rivaroxaban.
Objective: To evaluate the bioequivalence of rivaroxaban formulations manufactured by Eurofarma Laboratórios S/A and
the reference drug, Xarelto (Bayer) under fasting and fed conditions.
Methods: Three randomized, open label, balanced, 2 treatments, 4 periods, 2 sequences, single dose, full replicate, crossover
studies in 48 healthy adult human subjects under fed and fasting conditions for rivaroxaban 10 mg and 20 mg. Rivaroxaban
concentrations in plasma were determined using a validated HPLC-MS/MS method.
Bioequivalence Study of Two 80 Mg Valsartan Tablets Formulations in Healthy Chinese Subjects Under Fasting and Fed Condition
Objective: The purpose of this study was to compare the bioavalability between the two 80 mg Valsartan Tablets formulations and to evaluate the bioequivalence of Reference and Test formulations of Valsartan Tablets 80 mg in Healthy adult chinese Male and Female subjects under Fasting and Fed condition.
Effects of Enterotoxigenic Escherichia coli on haematological parameters, immunity, gut microbiota profile and metabolites in weaned Ningxiang piglets
The purpose of this study was to clarify the response of Ningxiang pig against pathogenic enterotoxigenic Escherichia coli
(ETEC) during the weaning period. Sixteen weaned Ningxiang pigs, were selected from one litter at 28 days and randomly
allocated into two groups, with or without oral administration of ETEC (109 colony forming units/piglet/d) for two
consecutive days. Blood and intestinal samples were collected after sacrifice to investigate the influence for systemic and
gastrointestinal tract influences
Assessment of Bacteriological Quality of Raw Bulk Milk of Camel, Cow and Goat from Local Markets in Yabello District, Borana Zone, Oromia Regional State
The study was conducted from September 2020 to June 2021 to assess the bacteriological quality of raw bulk milk from urban and rural local market sites in Borana pastoral area of Oromia Regional State, Southern Ethiopia. A total of 78 milk samples were collected and analyzed for bacterial load using standard plate count and coliform count techniques and isolation of pathogenic bacteria was conducted. The total mean aerobic bacterial counts of raw bulk milk samples of camel, cow and goat were 8.51 log cfu/ml, 8.73 log cfu/ml and 8.54 log cfu/ml respectively. Regarding the location of milk market sites, the mean total aerobic bacterial count was 8.72 log cfu/ml and 8.49 log cfu/ml in urban and rural milk market sites respectively. The total mean coliform counts of raw bulk milk samples of camel, cow and goat were 6.51log cfu/ml, 6.55 log cfu/ml and 6.47 log cfu/ml respectively. Regarding the location of milk market sites the total mean coliform counts was 6.63 log cfu/ml and 6.40log cfu/ml from urban and rural milk market sites respectively. Comparing the mean differences of the total mean aerobic and coliform bacterial counts, there was no significant mean differences (p>0.05) among the animal milk samples. However, there was significant mean differences (p<0.05) among the milk market sites. Different bacterial species were isolated from camel, cow and goat raw milk sample from the urban and rural milk market sites. The major bacterial isolates were Staphylococcus (both pathogenic and non-pathogenic), Escherichia coli and Bacillus species. Generally, the unhygienic milk handling resulted in poor milk quality in the pastoral area. Therefore, there is a need of training for persons at the various milk market sites on strict hygienic measures to improve the bacteriological safety of cow milk.
An Innovative Look at Buckling of Cracked Ghraphene Nano Sheets Using Novel Extended Molecular Mechanics Method
In this paper, we take a creative look at the effect of cracking on the buckling of graphene sheets. We introduced a significant improvement in molecular mechanical calculations that more accurately examine the behavior of atomic bonds during the instability of nanostructures in the presence of defects. A molecular mechanics method based on the modified couple stress (MCS) theory to consider the size effect on the graphene plate is introduced. Primary cracks with different lengths, orientations, and numbers were examined. For each crack, buckling parameters such as critical load and buckling modes of graphene sheets were investigated. This model has better computational performance and less computational compactness than other models. Our studies show that cracks perpendicular to the load direction have a greater effect on buckling parameters, including modes and critical buckling load than cracks aligned to the critical load.
Increasing the crack length will further reduce the critical buckling load. The effect of the number of cracks in two directions in buckling parameters was investigated. Increasing the number of cracks always decreases a critical buckling load. Increasing the number of cracks affects the first buckling mode more than others. The study of the eccentricity of cracks shows that with increasing the eccentricity distance, in cracks perpendicular to the loading direction, the critical buckling load will be further reduced. However, for cracks aligned with the load direction, increasing the eccentric distance has less effect on reducing the critical buckling load.
Evaluation of Characterization Results of Ru, Sb And V_Doped Sno2 Coatings Deposited by Using Produced and Commercial Targets
Ruthenium, Antimony and Vanadium doped and undoped tin oxide (SnO2) thin films were prepared by the R.F. Sputtering method. At the beginning of the thin film production studies, pellets were formed by pressing the filled and undoped tin oxide powders in the laboratory environment. The purpose of creating these pellets is to replace commercially purchased target material that acts as the coating material in the sputter coating device. The aim of the study is to use these pellets instead of this commercial target due to its disadvantages such as long lead time and expensiveness, and thus to produce easier, more diverse and high quality thin films. This study includes the synthesis of pure and doped thin films of tin oxide semiconductor material, which has a wide band gap and attracts attention with its wide spread use thanks to this feature, subjecting it to annealing process under different temperatures and times, and structural and morphological characterization studies: XRD, SEM, AFM, XPS, UV-Vis Spectrophotometer and Nano-hardness machine.
The study showed that doped and undoped tin oxide films showed similar properties to similar studies seen in the literature, so that the pellets formed in the laboratory environment functioned. No major structural difference was observed in the films produced as a result of the use of pellets and target. As a result of the findings of the study, it has been seen that it is a preliminary study for the investigation of gas sensing properties.
Maximal Distance of Splatters and Droplets Projections Produced by Dental Air and Water-Cooled Instruments Around a Dental Chair in an Open-Plan Area
A dental chair and its environment can be contaminated with droplet/splatter and aerosol particles, which contain various pathogens, including SARS-Cov-2, that can be transmitted by contact or inhalation. We aimed to evaluate the maximal distance of droplet/splatter projections for four different air and water-cooled dental instruments using a patient simulator, to define the boundaries of the open-plan area contaminated immediately after treatment.
We used a dental chair unit placed in a room in the open-plan area. Fluorescent powder was added to water, to know the maximal distance reached by the droplet/splatter on the surfaces of the dental room covered with white sheets.
Dental care was performed in an artificial mouth using either an air turbine handpiece, a high-speed electric contra-angle, an ultrasonic scaler, or an air/powder polisher with a constant volume of colored water. Maximal distances of droplet/splatter projections were measured after identifying the fluorescent patterns on the surfaces. Calculated heights and angles were then used after normalization to know the maximal distance that could be reached by these projections.
In these conditions, the theoretical maximal distance of droplet/splatter projection was 295 cm for the air-powder polisher, followed by 238 cm for the high-speed electric contra-angle, 93 cm for the air turbine and 77 cm for the ultrasonic scaler.
Theoretical projections for the ultrasonic scaler did not go beyond the dental room.
In our open-plan area, droplet/splatter projections can extend beyond the dental room entrance, but not over 1.80 m-high partitions, and could contaminate areas located nearby. Simple preventive measures would be to limit the perimeter of these projections, for example by installing a door, in addition to measures to limit the scope of aerosols.
Bioequivalence Study of Donepezil 10 mg Orally Disintegrating Tablets in Healthy Thai Volunteers Under Fasting Conditions
Donepezil is a potent, selective, noncompetitive and reversible inhibitor of acetylcholinesterase, commonly used for the treatment of Alzheimer’s disease. The form of orally disintegrating tablets (ODTs) is a good alternative dosage form for patients who have a difficulty in swallowing conventional tablets or capsules.
Association between Chronic Obstructive Pulmonary Disease Severity and Platelet Values
To investigate the association between platelet values and COPD severity using linear variables in order to
better explain and explore these correlations.
Comparative Effect of a High Fat with or without High Levels of Sucrose Diets on Peripheral Neuropathy in C57BL/6J Mice
Feeding mice a diet containing high fat and high sucrose has been promoted as a good model for type 2 diabetes. This study sought to determine the effect of feeding mice a high fat and high sucrose diet on neuropathy compared to mice fed only a high fat diet and mice fed a high diet and treated with streptozotocin.
HIV Screening Scenarios and Targets to Achieve 90% Sero-Status Knowledge Over 2021-2025 in Morocco – Pioneer Use Case of the Goals HIV Testing Strategies Model in a Concentrated Epidemic
Morocco applied the Goals testing model, projecting alternative testing scale-up scenarios, varying coverage targets for 13 adult populations. The model was calibrated using program service delivery, spending and surveillance data (2015-2019), integrated bio-behavioural surveys, and national HIV estimates. It projects annual diagnoses by target group from undiagnosed prevalence and testing coverage, allowing for HIV-infected people self-selecting for testing, retesting and transitions between groups. Scenarios were
evaluated for knowledge status improvement and cost, focusing on 2023-2025.
Reproduction and pre-weaning Growth Performances of Guinea Pigs (Cavia porcellus) Fed on the diets containing Ipomea batatas Leaves and/or Stylosanthes guianensis Meal
To contribute to the efficient satisfaction of nutrient needs of guinea pigs, a study on the effect of the inclusion of Ipomea batatas leaves
and Stylosanthes guianensis meal on the reproductive performance of guinea pigs was carried out between October 2019 and January
2020 in the Animal Production and Nutrition Research Unit of the University of Dschang. 80 guinea pigs including 64 females and
16 males weighing 448 ± 50 g and aged between 5 and 6 months were identified and distributed randomly into 4 groups of 20 animals
each.
Bioequivalence of Two Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate 600/200/300 mg Fixed-Dose Combination Tablets in Healthy Thai Male Volunteers under Fasting Conditions
Fixed-dose combination tablet formulation of efavirenz/emtricitabine/tenofovir disoproxil fumarate 600/200/300 mg is an antiretroviral
therapy comprising one non-nucleoside reverse-transcriptase inhibitor and two nucleoside reverse-transcriptase inhibitors to control
human immunodeficiency virus infection.
Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell
The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
Editorial Board Members Related to ETs
VOJTECH HAINER
Associate Professor
Institute of Endocrinology
Obesity Management Center
Prague
Czech Republic
Institute of Endocrinology
Obesity Management Center
Prague
Czech Republic
Charles J. Malemud
Professor
Department of Medicine and Anatomy
Case Western Reserve University
United States
Department of Medicine and Anatomy
Case Western Reserve University
United States
TIMUCIN UGURLU
Associate Professor
Department of Pharmaceutical Technology
Marmara University
Turkey
Department of Pharmaceutical Technology
Marmara University
Turkey
Makobetsa Khati
Department at CSIR Biosciences
Pretoria
South Africa
Pretoria
South Africa
Khalid M. El-Say
Associate professor
Department of Pharmaceutics and Industrial pharmacy
King Abdulaziz University
Saudi Arabia
Department of Pharmaceutics and Industrial pharmacy
King Abdulaziz University
Saudi Arabia
Younes Chorfi
Associate Professor
Department of Veterinary Biomedicine
University of Montreal
Canada
Department of Veterinary Biomedicine
University of Montreal
Canada
Tetsuya Yoshinaga
Professor
Institute of Health Biosciences
Tokushima University
Japan
Institute of Health Biosciences
Tokushima University
Japan
Rodrigo Fernandez Valdivia
Assistant Professor
Department of Pathology
Wayne State University School of Medicine
United States
Department of Pathology
Wayne State University School of Medicine
United States
ALAA EL-DEEN BAKRY YASSIN
Associate Professor
Department of Pharmaceutical Sciences
King Saud bin Abdulaziz University for Health Sciences
Saudi Arabia
Department of Pharmaceutical Sciences
King Saud bin Abdulaziz University for Health Sciences
Saudi Arabia
Anuradha Ratna
Department of Medicine
University of Massachusetts Medical School
USA
University of Massachusetts Medical School
USA