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To describe a case of a 39-years-old man with marked scleral thinning secondary to proton beam therapy for choroidal melanoma. Observations: The patient underwent multiple unsuccessful reconstructive surgical procedures complicated by failure and enucleation was finally suggested. However, he started improving following homologous serum drops administration

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Undernutrition is a leading cause of disease susceptibility, morbidity, and mortality in children. It is manifested in the form of stunting and wasting. Wasting is an acute form of undernutrition that indicates a recent food shortage and/or infectious diseases that lead to rapid and severe weight loss. The current study aimed to assess the prevalence and associated factors of stunting and wasting among under-five-aged children of displaced families in the North Gondar Zone. A cross-sectional study design was conducted from January to March 2022 among the under-five-aged children of the displaced family. A total of 205 randomly selected under-five-aged children from the displaced families were included in the study. A structured questionnaire was used to collect data, and the instrument was adopted from a previous study. Anthropometric measurements were carried out to determine the status of stunting and wasting. A bivariable and multivariable logistic regression analysis was used to find the factors associated with stunting and wasting. The prevalence of stunting and wasting among under-five-aged children was 26.2% and 18.7%, respectively. Out of the risk factors considered in the present study, age (AOR = 3.54; 95% CI: 0.2–3.54), family monthly income (AOR = 3.6; 95% CI: 1.3–7.5), eating only two meals per day (AOR = 2.8; 95% CI: 1.0–6.2), and not eating farm animal products (AOR = 2.2; 95% CI: 0.5–1.61) were important risk factors associated with stunting. In the other way, age, family monthly income, and eating only two meals per day were significant predictors of wasting. The result showed that the prevalence is severe in the study area. Therefore, the government should work on children under two years of age, take action to solve the nutritional issues, and encourage families with low monthly incomes to eat animal products at least once a week and nutritious food at least three times a day

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The determination of the postmortem interval (PMI) towards assisting in medicolegal investigations is a frequent requirement in any developed jurisdiction. Each of the latter has prevailing peculiarities, especially with many operating variables that include seasonal changes. There is a dearth of information about the decompositional pattern and progress of cadavers deposited on the ground in Nebraska, a jurisdiction lying within the Central Great Plains of North America. The present study, using an experimental pig was designed to consider the entomological peculiarities within a geographical area exhibiting taphonomic characteristics, and during a defined season.

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The aim of controlling/regulating cellular processes by surface patterning of biomaterials is a crucial concept in emerging research fields, where the precise fabrication of micro-nano surface topographies is required at manufacturing scales to meet consumer demand. Photolithography is typically employed for surface patterning; however, the high cost, process complexity, and lack of environmentally friendly and sustainable methodologies represent steep barriers for many researchers. Soft lithographic methods have been utilised extensively as a potential alternative for traditional photolithography, yet a photolithographic step is still required for initial template fabrication. Here, we demonstrate the use of repurposed optical consumer items such as DVDs, diffraction glasses, and gratings that would otherwise be thrown away after their useful lives, being used here as a sustainable approach as templates for the formation of complex nano-patterns. By replicating these templates in polydimethylsiloxane (PDMS) and polylactic acid (PLA), we show the varied interactions of human aortic smooth muscle cells (HAoSMC) to these surfaces. Notably, it was demonstrated that, in comparison to nonpatterned substrates, HAoSMC interaction (adhesion, spreading, and viability) was higher on DVD patterned surfaces compared to diffraction glass and grating patterned surfaces according to the results from cell metabolic activity (MTT and Alamar Blue), and proliferation (total DNA) assays. We demonstrate that a simple, reusable, inexpensive, yet robust technology could be a powerful tool in improving our understanding of cell-surface interactions and for the potential development of medical devices with micro- and nanoscale low or high adhesion features

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The main aim of this project is to formulate and evaluate Clindamycin peel-off gel face mask against Acne vulgaris. Peel off gel mask of Clindamycin phosphate was formulated using different excipients like Triethanolamine, Carbopol, Polyvinyl Alcohol, Glycerine, Xanthan gum, and Benzyl alcohol. Formulation of different composition of polymer was formulated and their pH, extrudability, homogeneity, spreadability, viscosity, washability and other parameters like drug content, permeability and drug release were evaluated. The result showed that the concentration of PVA and Carbopol which are the main polymers used in the formulations had effect on the drug content, drug release, permeability, spreadability and other parameters. The peel off mask prepared by using different concentration of these two polymers showed satisfactory result in all the evaluated parameters.

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Urinary stone is the presence of one or more stony concretes located at any level of a segment of the urinary tract. It is a worldwide problem that can affect all groups of ages and the prevalence has been increasing over time. Urolithiasis affects about 12% of the world population at some stage in their lifetime. Therefore, this study aimed to assess the prevalence and associated factors of urinary stone among adult patients attending in Tigray hospitals, Ethiopia.

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Grapes (Vitis vinifera L.) are among the most commonly cultivated horticultural crops on the earth covering an area of 7.5 million hectares with around 70 million tons production. Grapes being highly nutritious are majorly utilized in making beverages or used as fresh and raisin. In today’s world, the most concerned topic in agriculture is continuous change in climatic conditions leading to several negative social, ecological, economical and biological problems. Grapes are delicate fruits, their vines are sensitive towards extremes in temperature, water, heat, duration and intensity of light exposure as well as carbon dioxide and humidity alterations. Hence, one can shift to drought and heat tolerant varieties and certain training and pruning methods suitable to the prevailing environmental conditions. Vineyard management practices, including farm mechanization can be amended for improving the gains, while reducing the input

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The vibrations of carbon nanotubes under the influences of various internal and external forces have been subjects of interests for some years. These researches have not really considered the effects of surface energy and initial stress which are very important from both material and mechanical aspects of views. Therefore, the current study presents the simultaneous impacts of surface energy, initial stress and nonlocality and other various parameters on the nonlinear vibration of carbon nanotube hot fluid-conveying resting on elastic foundations in a magnetic environment. The derived equations governing the behaviours are solved using Galerkin’s decomposition-Adomian decomposition method is adopted to explore the concurrent impacts of surface elasticity, initial stress, residual surface tension and nonlocality on the nonlinear vibration of singlewalled carbon conveying nanotube resting on linear and nonlinear elastic foundation and operating in a thermo-magnetic environment

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A cross-sectional study was conducted to assess food habits among college students at Kuwait University (KU) utilizing a written questionnaire, targeting first year to higher education level regardless of age. Participants were recruited from different colleges (n=678) (73%, females, and 27% males) with a response rate of 98.8%. Data showed that 48.6% buy their foods from campus, and 38.2% of them eat in college daily. The taste was the most influential factor that is affecting food choices (53.7%), while only 2.9% of students considered cost as an important element

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Justificative: This trial was conducted in order to register a new generic product of Rivaroxaban. Objective: To evaluate the bioequivalence of rivaroxaban formulations manufactured by Eurofarma Laboratórios S/A and the reference drug, Xarelto (Bayer) under fasting and fed conditions. Methods: Three randomized, open label, balanced, 2 treatments, 4 periods, 2 sequences, single dose, full replicate, crossover studies in 48 healthy adult human subjects under fed and fasting conditions for rivaroxaban 10 mg and 20 mg. Rivaroxaban concentrations in plasma were determined using a validated HPLC-MS/MS method.

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Pyoderma gangrenosum is a rare ulcerating skin disease often presenting as an extra intestinal manifestation of IBD and is difficult to manage. Treatment options for pyoderma gangrenosum include steroids, calcineurin inhibitors and anti TNF agents. Here in, we report a case of recurrent Pyoderma gangrenosum with Ulcerative Colitis that was successfully managed with Tofacintib, a JAK inhibitor

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Supraventricular tachycardia is the most common type of tachyarrhythmia seen in childhood. First-line treatments (adenosine, esmolol-propranolol, digoxin, electrical cardioversion) usually suppress tachycardia, but rarely tachycardia is resistant and requiring Class IC and/or Class III agents, such as amiodarone, sotalol, propafenone, and flecainide.

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According to the UNAIDS 2022 report, 52% of the HIV positive children between 0-14 years were able to access treatment and of these 68% attain viral suppression. CCR5 promoter genotype specifically single nucleotide polymorphisms have been linked to modulate patient virological status. However, the few studies that have studied the association in infants have utilized allele-specific PCR a genotypic method limited to detecting already known SNPs. By using Sanger sequencing, we explored the association taking into account novel mutations.

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Two basic reactions occur during the anodizing of aluminum: 1) the aluminum is consumed and 2) an oxide grows. By accepting this statement as true, the anodizing process can be viewed as a corrosion process, and anodizing can be modeled using the Tafel Equation. Anodizing process parameters of electrolyte chemistry and concentration, temperature, aluminum substrate resistance and current density are presented as they relate to the Tafel Equation and how they impact the anodic aluminum oxide structure and properties. Understanding this relationship is consequent in making anodizing an engineering process, one that enables tuning the structure such that it yields distinct characteristics to fulfill design and application requirements.

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Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.

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The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.

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The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.

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The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.

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Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.

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We investigated a method for preparation of ordered nanopore arrays with the interpore distance of 60 nm by guided self-organization of anodic aluminum oxide with a prepatterned array of pits in the starting Al film.

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The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.

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Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.

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Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.

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