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Beneficial Effects of Vitamin E against Indomethacin-induced Glutathione Depletion, Acetylcholinesterase Activity, (Na+,K+)-ATPase Activity and Osmotic Fragility of Erythrocyte

Indomethacin, is a well-known non-steroidal anti-inflammatory drug (NSAID), a cyclooxygenase inhibitor and extensively used as a medicine to reduce pain, fever, stiffness, swelling or inflammatory responses. Indomethacin inhibits both COX-1 and COX-2, which in turn, inhibits the production of prostaglandins in the gastrointestinal tract and disrupts the mucosal lining in the gastrointestinal tract leading to intestinal bleeding and perforation.
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New Technologies of Crystallization of Sucrose as Fundamental Factor of Increase in Economic Efficiency of Sugar Branch

In recent years sugar industry of the Russian Federation violently develops, showing positive effect in development of finished product. The modern crystallization of sucrose is based on two fundamental processes: periodic and continuous boiling of sugar massecuites. A traditional (typical) crystallization of sugar for these years undergone serious modernization as from the point of view of the technology, and equipment.
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Adolescent Smoking: The Relationship between Cigarette Consumption and BMI

Studies relating cigarette smoking and body weight yield conflicting results. Weight-lowering effects in women and men have been associated with smoking; however, no effects on weight have been proven. This study examined the association between cigarette smoking and relative weight in adolescent males and females as they age into young adults.
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Hypovolemic Shock Following Subgaleal Hemorrhage with Associated Hypoxic Ischemic Encephalopathy in a Term Infant

We are reporting an infant who was born by emergency cesarean section following failed vaginal delivery. This infant was noted to be in hypovolemic shock soon after birth. He developed large subgaleal hemorrhage within 6 hours after birth with associated diffuse intravascular coagulopathy and hypoxic-ischemic encephalopathy. He required multiple transfusions of packed red blood cell, platelets transfusion, fresh frozen plasma transfusions, and a cryoprecipitate. The infant was on body cooling therapy for hypoxic ischemic encephalopathy for three days. His neurological exam at the time of discharge was unremarkable. At the time of discharge, an infant is enrolled in an early intervention program with a multi-disciplinary follow-up scheduled.
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The ACAI (Euterpe oleracea Mart.) Pulp Consumption Improves Blood Pressure Levels in Women with Higher Concentrations of Interferon-Gamma

Interferon-gamma (IFN-γ) is associated with the inflammatory responses modulation, which could culminate in chronic metabolic diseases. In this context, the aim of the present study was to evaluate the effect of the acai (Euterpe oleracea Mart. mart.) pulp consumption on the anthropometric, clinical and biochemical parameters in women clinically healthy, with IFN-γ, respectively, smaller and higher than 5 pg/mL. Twenty four women in G1 (with IFN-γ concentrations smaller than 5 pg/mL) and sixteen in G2 (with IFN-γ concentrations greater than 5 pg / mL), consumed 200g per day of acai pulp during four weeks. Anthropometric and body composition measurements, biochemical and clinical data were evaluated before and after the intervention
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Assessment of Dietary and Total Greenhouse Gas Emissions from Group of Twenty (G20) and the World

Correlation formulas are developed to estimate the dietary and total greenhouse gas emissions (GHGEs) from Group of Twenty (G20) and the world in 2014 and 2017 using personal meat consumption as the required input. Among the 43 states involved in G20, the 28 states of the European Union (EU28) are considered as a whole. Based on 47,381 dietary survey samples, a formula is developed to establish the relationship between the meat consumption and GHGEs from human dietary and total activities.
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Air Pollution Report of Agartala city Tripura, India

Air pollution is a major and growing risk factor for ill health in India, contributing significantly to the country’s burden of disease. As per the Global Burden of Disease comparative risk assessment for 2015, air pollution exposure contributes to approximately 1.8 million premature deaths and 49 million disability adjusted life-years (DALYs) lost, ranking it among the top risk factors for ill health in India. Home to 10 of the top 20 cities with the highest annual average levels of PM2.5 as per the WHO Urban Ambient Air Quality Database (2016), and with several studies showing a worsening trend over the time, it is safe to say that rapid urbanization and industrial development have adversely affected urban air quality due to vehicular and industrial emissions. Simultaneously, over two-thirds of rural Indians caught in the ‘chulha trap’ use biomass fuels such as wood, dung or coal to satisfy their cooking and heating needs, resulting in smoke-filled homes and extremely high levels of exposure especially to women and children [1]. With respect to other cities of India, our smallest state Tripura (Agartala city) also have the high value of PM10 & PM2.5.The value of particulate matter is above the CPCB standards and also WHO standards. On the Basis of the study report we made some suggestion to overcome these conditions.
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An Investigation into the Range of Movement and Forces Involved by the Application of Wrist Flexion Restraint Techniques - Pain Inducing or Not?

Although the use of physical restraint (PR) is accepted, it remains controversial as staff are required to balance professional, ethical and legal tensions between maintaining everyone’s safety, upholding human rights, and minimising harm. One such tension relates to the use of Wrist Flexion Techniques (WFT) used in some health, social care and custodial settings. WFT impose load onto the musculoskeletal structures of the wrist to gain control or compliance from a restrained person, and can result in discomfort, pain, injury, psychological trauma and be detrimental to therapeutic relationships. Current evidence and guidance on WFT are absent with debate existing as to whether WFT can be used without inducing pain. Twenty adults participated in the study. The mean discomfort angle was 90.1° (± 8.6) of flexion with 2.8 Kg (± 1.1) of force, and the mean pain angle was and 98.4° (± 7.9) of flexion with 4.4 Kg (± 1.8) of force, therefore only 8.3° of movement and 1.6 Kg of force separate pain free from pain inducing WFT. Genders did not differ in relation to angle of discomfort or pain. Females experienced discomfort with 1.1Kg less force (p = 0.021) and experienced pain with 1.7Kg less force (p = 0.023). This research challenges the assertion that WFT can exist as non-pain inducing and pain inducing PR techniques since the margin between them may be too small for practitioners to discriminate, particularly during the struggle of real world restraint. Further research may consider other potential pain inducing techniques, and the role and use of PIT during restraint.
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Preliminary Investigation of the Interaction of Misoprostol and Phenylbutazone on Bone Response to Injury in Horses

Phenylbutazone (PBZ) is commonly used in equine patients for treatment of orthopedic injuries. Phenylbutazone may adversely affect bone healing because of suppression of prostaglandin production. We hypothesized that administration of the prostaglandin analog misoprostol would enhance bone healing and mitigate the untoward effects of PBZ on bone response to injury in horses. The objectives of this study were to determine whether the administration of misoprostol would enhance bone healing and whether concurrent administration of PBZ and misoprostol would mitigate the untoward effects of phenylbutazone. Twenty horses were randomly assigned to one of four groups (n=5 per group): Group 1 (untreated control), Group 2 (phenylbutazone alone), Group 3 (misoprostol, alone), or Group 4 (concurrent treatment with phenylbutazone and misoprostol). A 4.5-mm diameter uni-cortical bone defect was created in one metacarpal III bone of all horses. Fluorochromic bone labels were administered intravenously on Days 0, 7, and 14. Computed tomographic osteoabsorptiometry and histomorphometric analyses were performed on the harvested metacarpal bones. Phenylbutazone treatment caused a decrease in endosteal new bone formation. Administration of misoprostol appeared to mitigate the magnitude of the PBZ effect on new bone formation (endosteal in-growth, p<0.06). Bone specific alkaline phosphatase serum activity decreased throughout the 14-day period of stall confinement. Mineral apposition rates increased in all groups during the period from 7 to 14 days after bone injury. Further research is needed to determine if this effect is significant. The administration of misoprostol may be beneficial to lessen the undesired impact of phenylbutazone on bone healing in horses.
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The Combined Effect of Organic and Inorganic Fertilizer on Yield and Yield Component of Cabbage (Brassica Oleracea) at Dedebit Central Tigray, Ethiopia

The use of organic fertilizer as an alternative to inorganic fertilizer increased among subsistence farmers in rural areas in meremieti. Despite the fact that, no clear recommendation exist for the application of rate of organic fertilizer on vegetable. Field experiment was conducted to evaluate the different combination of organic and inorganic fertilizer on yield and yield component of cabbage.
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Is there Correlations among SLEDAI, Pro-Inflammatory Biomarkers and Urine NGAL in SLE?

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease. Several indexes can measure SLE activity, and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) is one of them. The aim was to associate SLEDAI with inflammatory biomarkers present in serum (C3, C4, CH50, C-reactive protein, and creatinine), proteinuria (urine 24h) and urine NGAL in SLE patients. This study included 43 SLE patients who were arranged in two groups according to the value of SLEDAI. One group, SLEDAI 0-4 (n=25), included SLE patients with low activity, and the other group, SLEDAI >4 (n=18), included SLE patients form moderate to high activity. Level of urine NGAL (uNGAL) was determined by ELISA, and the data were analyzed using GraphPad Prism 5.
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Some Significant Developments in Bandage Fabrics

The article provides some useful insights on bandage cloths as pointed out by some significant researches. Some work has been focused on medical bandages. In the construction of bandages, cotton, bamboo and cotton/bamboo have been selected. In order to enhance the functional properties finish has been given that include antimicrobial using triclosan, vitamin E and aloe vera. The woven bandages have been tested for antimicrobial activity, comfort and aesthetic property.
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Access to and Utilisation of Adolescent Sexual and Reproductive Health Services among Secondary School Students in Mityana district, Uganda

The study of the access to and utilisation of Adolescent Sexual and Reproductive Health (ASRH) services among secondary school adolescents in, Mityana district was carried out in various schools in Ssekanyonyi sub-county. The study aimed to determine the prevalence of the ASRH burden, assess the utilisation of ASRH services in these schools and identify drivers/barriers to the utilisation of ASRH services among adolescents in secondary schools in Mityana district.
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Accidentally Discovered Pure Squamous Cell Carcinoma of the Gall Bladder: A Case Report

Squamous cell carcinoma of the gallbladder is rarely reported, comprises less than 1% of all gall bladder cancer and portends a worse prognosis than the more common adenocarcinoma. We report a 80-year-old female who presented with acute onset epigastric pain. She was operated on based on a presumptive diagnosis of acute on top of chronic cholecystitis with cholelithiasis according to clinical and ultrasonographic findings. Histopathological examination of the thickened wall of the gallbladder revealed well to moderately differentiated keratinized squamous cell carcinoma invading full wall thickness and infiltrating the liver. Further examinations revealed no other primary site for the tumour. Gallbladder cancer should be considered as part of the differential diagnosis in elderly patients presenting with cholecystitis.
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Veterinary Considerations for the Theoretical Resurrection of Extinct Species

The de-extinction of the dinosaur is a dubious possibility but its consideration brings forth some issues that are at least worthy of scientific discussion. In this review, we discuss two distinct issues that have implications for a de-extinct species such as a dinosaur: the ability, or lack thereof, to safely sedate a rare and potentially fractious animal capable of harming the veterinary staff tasked with its care; and, disease risks associated with a species that has been extinct for millions of years. To identify potential sedatives, comparative pharmacology will be needed to uncover the links between receptor pharmacology and the desired clinical outcomes of activating established alpha-2 adrenergic, opioid, and benzodiazepine receptors. Specific to disease control, it will be necessary to understand the unique susceptibility of the new species to current diseases as well as predicting their reservoir capacity for potential human and veterinary pandemic diseases. While the topics presented herein are not exhaustive, this review highlights some of the foremost research that should be conducted in order to serve the unique veterinary needs of a de-extinct species using the dinosaur as a paradigm. Addressing these issues should be considered if an intact dinosaur genome becomes available, regardless of the feasibility of dinosaur resurrection.
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Ordered Growth of Anodic Aluminum Oxide in Galvanostatic and Galvanostatic-Potentiostatic Modes

The results are presented of obtaining anodic aluminum oxide with an ordered pore arrangement by employing two anodizing modes - galvanostatic mode and combined (galvanostatic + potentiostatic) mode, at high values of the current density and voltage. Use has been made of an oxalate electrolyte and a complex electrolyte comprising oxalic acid and phosphoric acid. Scanning electron microscopy has been used to investigate the surface morphology of the barrier and porous layers and to determine pore sizes and inter-pore distance.
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Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
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Analysis of Sweat Simulant Mixtures using Multiplexed Arrays of DNA-Carbon Nanotube Vapor Sensors

Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological samples.
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
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Fabrication of Vertical Cu2ZnSnS4 Nanowire Arrays by Two-Step Electroplating Method into Anodic Aluminum Oxide Template

Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.
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Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions

Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
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Editorial Board Members Related to GA

Jonathan Scott Harrison

Professor
Division of Hematology/Medical Oncology University of Missouri
United States

Daniela Iannazzo

University Researcher
Department of Electronic Engineering, Industrial Chemistry and Engineering
University of Messina
Italy

Akram Mahmoud El-Abd Asbeutah

Assistant Professor
Department of Radiologic Sciences
Faculty of Allied Health Sciences
Kuwait University
Kuwait

Jason W. Locasale

Assistant Professor
Division of Nutritional Sciences
Cornell University
United States

ARA ANTONYAN

Associate Professor
Department of Biophysics
Yerevan State University
Armenia

Mohamed Maarouf Ali Zeinhom

Associate Professor
Food Hygiene Department
Faculty of Veterinary Medicine
Beni-Suef University
Egypt

Ki Baik Hahm

Professor
Cancer Prevention Research Center
CHA University
Korea

Andrey Budanov

Assistant Professor
Department of Human and Molecular Genetics
Massey Cancer Center
United States

Khue Vu Ngyen

Departments of Medicine and Pediatrics
University of California
USA

Jianguo Zhang

Associate Professor
School of Computing
University of Dundee
United Kingdom
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