Top Links

Articles Related to GA

The Use of Gingipain DNA Vaccine Against Virulence of Porphyromonas Gingivalis: A Literature Review

Porphyromonas gingivalis (P. gingivalis) is a primary etiologic agent of generalized aggressive and chronic forms of periodontitis. It releases toxins called ‘gingipains’.Gingipains, (Arginine-and Lysine-specific cysteine proteinases) are proteases that are critical virulence factors in progression of periodontitis and degradation of cytokines expressed during inflammation. HRgpA and RgpB (products of two distinct but related genes) induce vascular permeability by activation of the kallikrein/kinin pathway and activating the blood coagulation system which in turn induces gingival crevicular fluid production and progression of inflammation leading to alveolar bone loss.
View complete article: PDF  |  Full-text

A Review on Antioxidant, Anti-Inflammatory and Gastroprotective Abilities of Mango (Magnifera indica) Leaf Extract and Mangiferin

Mango (Mangifera indica Linn.) trees have been cultivated and grown in Southern and Eastern India for thousands of years and have slowly spread all over the world. For over 4,000 years various parts of mango trees including leaf and fruit pulp have been extensively used in Ayurvedic and Unani medicines.
View complete article: PDF  |  Full-text

Timing is everything: Lipid and Energy Losses with Simulated Nasogastric Tube Feeds

To determine the proportion of human milk (pooled and homogenized) fat loss via feeding tube in a simulated 24-hour feeding cycle. Anonymous samples of frozen human milk were obtained, thawed and pooled (pHM) in a 1000 mL glass beaker with a magnetic stir bar. Eight syringes (30 mL each) were prepared and attached to 60” extension tubing and a 5 FR polyurethane or silicone nasogastric (NG) tube. Samples to test for pool uniformity were collected at the beginning, middle and end of syringe preparation. Milk was delivered sequentially via gravity, 30-minute or 60-minute infusion. Pooled human milk was analyzed for macronutrient content at the end of each feeding “cycle”. All scenarios were repeated using homogenized donor human milk (hDHM).
View complete article: PDF  |  Full-text

Principal Time-Use and School Efectiveness at Gabi-Rasu Zone Secondary Schools

Principals have different duties and responsibility to heads of schools. To better understand the allocation of their time work within the work day lives of principals, this study uses self-rating time-use data for secondary school principals in Gabi-Rasu Zone, Afar national regional state, Ethiopia. This study examines the relationship between the time principals spent on different types of activities and school outcomes including student achievement general education secondary school examination (GESSE) test score. We find that time spent on organization management activities, administration activities, instructional program activities, day-to-day instructional activities, internal relation activities, external relation and other activities are associated with school outcome (student test score). The researcher used a descriptive research design of survey type and gathered data through self-rating time usage data. The sample of this study comprises school principals in the Gabi-Rasu Zone. Thus, eleven public general preparatory secondary high school, two private general secondary high school and fifteen public general secondary high school. There are four research questions were guided this study. The data collected were analyzed through the computation of descriptive statistics, t-test, and contingency table and Univariate correlation. Findings indicated significant relationships between principal time-use and school effectiveness, principal effectiveness, proportion of time of different activity and activities that principals often engaged.
View complete article: PDF  |  Full-text

Internal Inflammatory Root Resorption. Management with Mineral Trioxide Aggregate and Gutta-Percha

Early diagnosis and accurate treatment are essential for Internal Inflammatory Root Resorption (IIRR) control. The aim is to present the sequence of diagnosis, treatment and follow-up of an IIRR using gutta-percha (GP) and Mineral Trioxide Aggregate (MTA) as obturation materials. This study exhibits an IIRR case in the #9 tooth of a 64-year old patient. History refers to a horse’s kick suffered ten years earlier. The tooth was asymptomatic during the interim time period but eventually the patient experienced symptomology. Following a detailed exam, a treatment plan was reached to save the tooth and maintain its functionality.
View complete article: PDF  |  Full-text

Risky Sexual Practices among Adolescents Living with HIV Accessing HIV and AIDS Care Services at Health Facilities in the Central Region of Uganda

Adolescents living with HIV in Uganda are sexually active just like their uninfected peers. With the availability of antiretroviral therapy (ART), the surviving population of adolescents prenatally infected with HIV is increasing and they are becoming sexually active.
View complete article: PDF  |  Full-text

Caenorhabditis elegans (C. elegans) Used as a Whole Model Organism to Identify New Anti-Infectives Therapeutic Agent for MRSA Pathogens - A Review Paper

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the greatest fears with the number of serious infections on human health regarding antibiotic resistance. It causes a wide range of infections and bacteremia, ranging from inconsequential superficial skin infections, wound suppuration, even pneumonia or deep-seated tissue infections, which may lead to sepsis and fatalities.
View complete article: PDF  |  Full-text

Estimation of Beta-Lactam Antibiotics-Serum Albumin Conjugated Proteins by High Performance Liquid Chromatography with Ultraviolet Detector

β-lactam antibiotics represented the oldest class of antibiotics used in the treatment of infections in a human being, livestock, and aquaculture. Drugs residues in the edible tissues or foodstuffs of animal pose a potential threat to human health. At present, extensive antibiotic-resistant strains are now being detected and the development of antibiotic-resistant strains of epidemic and zoonotic pathogens is a major concern. Therefore, the purpose of this study was to estimate the extent of β-lactam antibiotics-HSA/BSA conjugations via three conjugation methods by using high-performance liquid chromatography (HPLC) with ultraviolet (UV) detector. We wish that the technique will be applied to preliminarily detect the residues of β-lactam antibiotics may persist in edible tissues or foodstuffs in the livestock and aquaculture farms in clinical.
View complete article: PDF  |  Full-text

Analysis of antibody by Real-Valued Special Functions

Along with the rapid development of genetic engineering technology and antibody engineering technology, the humanized monoclonal antibody has been rapidly developed and gradually replaces the rat sourced monoclonal antibody. In this paper, we establish two new logarithmically completely monotonic functions involving the real-valued special functions according to two preferred interaction geometries, necessary and sufficient conditions are presented for one of them to be logarithmically completely monotonic. As a consequence, a sharp inequality involving the real-valued special functions is deduced to solve the problems of genetically engineered antibody.
View complete article: PDF  |  Full-text

Night Shift Work and Weight Gain among Female Filipino Nurses

There are increasing numbers of overweight and obese nurses working the night shift. The purpose of this correlational and cross-sectional study was to determine if there are statistically significant associations between insufficient sleep, abnormal eating patterns, working 12-hour shifts, years of working night shift, age, stress, marital status, nursing units, decreased physical activity, and level of weight gain among female Filipino nurses working the night shift in the hospital. The theoretical foundation of this study was locate evidence, evaluate evidence, assess evidence, and informed decision model. An online survey through Survey Monkey was used to access nurses via a convenient sampling. Data were analyzed using Spearman correlation, multiple regression, and ANOVA. According to study findings, there were significant associations between insufficient sleep, abnormal eating patterns, marital status, 12-hour shifts, number of years working on night shift, and increased in body mass index. The implications for social change include information that nurses can use to better understand the negative implications of night shift work on health. At the organizational level, this study provides information for administrators and nursing leaders that might facilitate change in policies by improving working conditions for nurses.
View complete article: PDF  |  Full-text

Cubic Averaging Aggregation Operators with Multiple Attributes Group Decision Making Problem

The group decision making is a very useful technique for ranking the group of alternatives, the cubic averaging operator is new tool in group decision making problems. In this article, we develop a series of new operators so called cubic weighted averaging (CWA) operator, cubic ordered weighted averaging (COWA) operator and cubic hybrid averaging (CHA) operator. We also discussed some particular cases and properties of these operators. Furthermore, we apply the proposed aggregation operators to deal with multiple attribute group decision making in which decision information takes the form of cubic numbers. Finally, we used some practical examples to illustrate the validity and feasibility of the proposed methods by comparing with other methods.
View complete article: PDF  |  Full-text

Successful Treatment of Acquired Amegakaryocytic Thrombocytopenia (AAT) with Cyclosporine and Eltrombopag: A Case Report

Acquired amegakaryocytic thrombocytopenia is an unusual hematological disorder characterized by severe thrombocytopenia in association with a marked decrease, or the absence, of megakaryocytes in bone marrow. Its pathogenesis is not well understood and its clinical course is variable. Several treatments have been used, producing different responses. We present a case that was successfully treated with a calcineurin inhibitor combined with a thrombopoiesis-stimulating agent.
View complete article: PDF  |  Full-text

Endocardial Approach for Substrate Ablation in Brugada Syndrome: Epicardial, Endocardial or Transmural Substrate?

Background: Radiofrequency ablation (RFA) in Brugada syndrome (BrS) has been performed both endocardially and epicardially. The substrate in BrS is thus unclear. Objectives: To investigate the functional endocardial substrate and its correlation with clinical, electrophysiological and ECG findings in order to guide an endocardial ablation. Methods: Thirteen patients (38.7±12.3 years old) with spontaneous type 1 ECG BrS pattern, inducible VF with programmed ventricular stimulation (PVS) and syncope without prodromes were enrolled. Before to endocardial mapping the patients underwent flecainide testing with the purpose of measuring the greatest ST-segment elevation for to be correlated with the size and location of substrate in the electro-anatomic map
View complete article: PDF  |  Full-text

The Efficacy and Safety of Prophylactic Fluconazole Prevent Invasive Fungal Infection in Preterm Very Low Birth Weight Infants: An Update Meta-analysis

We identified 8 eligible trials that enrolled 1392 infants. There was significant effect of prophylactic fluconazole on fungal colonization (RR, 0.31, 95%C1:-0.24 to 0.41; P<0.00001). Effect of prophylactic fluconazole on IFI in VLBW infants: RR: 0.42(95%CI 0.23 to 0.76; P=0.004.). However, prophylactic fluconazole did not reduce mortality in VLBW infants (RR 0.76, 95% CI 0.58 to 1.01; P = 0.06). Studies did not report significant adverse reactions.
View complete article: PDF  |  Full-text

Trial on the Efficiency of Topline® Against Natural Tick Infestations of Dromedaries in Mauritania

Topline®, as a 1% “pour-on” solution of fipronil, is produced by MERIAL Company. Fipronil is an acaricide used to control ticks and biting flies of cattle. Dromedaries are regularly infested by ticks. The effectiveness and residual activity of fipronil as a 1% w/w pour-on formulation (Topline®) was studied in a trial on ticks of calves of dromedaries near Nouakchott, Mauritania.
View complete article: PDF  |  Full-text

Ordered Growth of Anodic Aluminum Oxide in Galvanostatic and Galvanostatic-Potentiostatic Modes

The results are presented of obtaining anodic aluminum oxide with an ordered pore arrangement by employing two anodizing modes - galvanostatic mode and combined (galvanostatic + potentiostatic) mode, at high values of the current density and voltage. Use has been made of an oxalate electrolyte and a complex electrolyte comprising oxalic acid and phosphoric acid. Scanning electron microscopy has been used to investigate the surface morphology of the barrier and porous layers and to determine pore sizes and inter-pore distance.
View complete article: PDF  |  Full-text

Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
View complete article: PDF  |  Full-text

Analysis of Sweat Simulant Mixtures using Multiplexed Arrays of DNA-Carbon Nanotube Vapor Sensors

Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological samples.
View complete article: PDF  |  Full-text

Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
View complete article: PDF  |  Full-text

Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
View complete article: PDF  |  Full-text

Fabrication of Vertical Cu2ZnSnS4 Nanowire Arrays by Two-Step Electroplating Method into Anodic Aluminum Oxide Template

Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.
View complete article: PDF  |  Full-text

Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions

Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
View complete article: PDF  |  Full-text


Editorial Board Members Related to GA

Prakash Prajapat

Assistant Professor
Department of Chemistry
Mehsana Urban Institute of Sciences
Ganpat University
Gujarat.

Kornélia Tekes

Professor
Department of pharmacodynamics
Semmelweis University
Hungary

Esam Hosney Ali Ibraheem

Professor
Department of Botany and Microbiology
Assiut University
Egypt

Chunying Li

Assistant Professor
Department of Biochemistry and Molecular Biology
Wayne State University School of Medicine
United States

Dong-Hua Yang

Assistant Professor
Fox Chase Cancer Center
United States

Maria Ioannou

Senior Lecturer
University of Huddersfield
United Kingdom

Zhonghua Sun

Associate Professor
Department of Imaging and Applied Physics
Curtin University
Australia

Sobhi M. Gomha

Professor
Chemistry Department
Faculty of Science
Cairo University
Egypt

WILLIAM FRAZER MORRIS

Professor
School of Osteopathic Medicine
Campbell University
United States

Marwa Hamdy El-Wakil

Faculty of Pharmacy
Pharmaceutical Chemistry Department
Alexandria University
Egypt
Submit Manuscript