Articles Related to GC

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In order to successfully counter the ever-growing drug problem, there is an increasing need, to identify conspiracy links and trafficking routes and to gather background intelligence concerning both the number of sources of drugs and whether those sources are within a country or are “internationally” based and also the points of distribution and distribution networks. A scientific tool to complement routine law enforcement investigative work in this field is the characterization and impurity profiling and cutting agents of seized drugs. Drug characterization studies have shown that it is possible to link samples, to classify material from different seizures into groups of related samples and to identify the origin of samples. Such information can be used for evidential (judicial, court) purposes or it can be used as a source of intelligence to identify samples that may have a common origin or history.

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Monocrotophos is a extremely hazardous organophosphate insecticide that is extensively used and easily accessible in India.

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Forensic Scientists are required to identify an ever increasing and more complex assortment of drugs and related compounds.

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This study investigates proximate composition and characterization of Moringa oleifera seed-oil using four methods of extraction (Cold pressing (CP), Enzyme assisted cold pressing (EACP), Enzyme assisted aqueous extraction (EAAE) and solvent extraction (SE)) and compared with olive oil. The results of proximate analysis of the kernel reveals (7.20 moisture content, 43.12 protein, 33.16 fat, 3.51 Ash, and 6.81 Carbohydrate by difference) %, while the oil yield obtained for CP, EACP, EAAE and SE were (7.75, 12.08, 23.25 and 33.16)%. The fatty acids composition and bioactive compounds were determined through GC-MS analysis. Melting and crystallization temperature ranges: -15.86 to 3.21 and 8.30 to -13.63 °C, respectively. There is a significant difference in term of oil yield, with cold pressing method having the lowest oil yield of 7.8 %. However, the quality of CP extracted Moringa oleifera oil was compared with virgin olive oil; it revealed its potentials as a good source of oleic acid making it to be a good substitute for virgin olive oil.

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Introduction: Among the neuroinflammatory disorder of CNS, Acute Disseminated Encephalomyelitis (ADEM) is a multifocal, subacute or acute onset disease that has got current interest of neurologists for its better outcome. Very few studies have been carried out on ADEM particularly in adults of our country. So we performed the study to describe short term motor outcome of hospital admitted ADEM patients.

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To evaluate the value and safety of labetalol in comparison to Alfa methyldopa in treatment of pregnant women with pregnancy-induced hypertension (PIH). 264 patients with PIH were randomly distributed to take either methyldopa (group 1) labetalol (group 2). or Intake of medications with respect to Age, gravidity, Blood Pressure measurement, albumin in urine measurement Levels, Side Effects, dose of the drug, increasing duration of pregnancy, mode of delivery, Perinatal safety and APGAR scores were studied. The statistical level of significance was taken at P<0.05.

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There has been little advance in embryo selection criteria since the first IVF. To this day, we select embryos by morphological criteria, which provide little information as to the actual embryo quality.

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Human epidermal growth factor receptor 2 (HER2) is responsible for the pathogenesis and poor outcomes of several types of cancers, including advanced gastric and gastroesophageal junction cancer. Molecular-targeted drugs on the other hand, such as trastuzumab, prolong overall survival and progression-free survival in HER2-positive gastric cancer. The purpose of the case report is to evaluate the impact of delivering trastuzumab in advanced gastric cancer with concomitant HER2 mutation and amplification.

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Sjögren syndrome (SS) is chronic, systemic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands. It is an elaborate involvement of the lacrimal and salivary glands, which eventually lead to keratoconjunctivitis sicca and xerostomia.

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The use of real explosive materials for canine training involves inherent dangers, toxicity risks exposure, and often limited availability of the training material all of which may affect the reliable training of canine teams. For this reason, the development of a training aid suitable for daily operations is beneficial to provide safe and effective explosive detection training that can provide for enhanced detection capabilities.

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White adipose tissue (WAT) is an endocrine organ with crucial role in the development of obesity and related diseases. White adipocytes have less mitochondria than brown adipocytes; nevertheless, there is an increasing body of evidence showing that mitochondrial parameters play a relevant role in WAT physiology, such as proliferation, differentiation and triacylglycerol storage levels.

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Cefpodoxime proxetil (CFPD PRXL) is broad spectrum, third generation cephalosporin; antibiotic. It is extremely bitter taste resulting in poor patient compliance. The aim of the present work was to prepare drug resin complex (DRC) using ion exchange resin (Kyron T-114) for taste masking and formulate oral reconstitutable suspension of DRC.

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Immunohistochemistry (IHC) was used to determine the protein levels of p27, CD117 and ki67 in tumor tissue of xenograft. After treatment of Fan, the morphologic changes were observed by DAPI staining, Hoechst staining and TUNEL detection under fluorescent microscopy.

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Use of gas chromatography (GC) combined with time-of –flight mass spectrometry (TOFMS) with soft ionization generated with three different plasma gases (i.e., Xe, Kr, Ar) was evaluated for the identification of several pyrrolidinophenone-type designer drugs that are commercially available.

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Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.

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Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological samples.

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The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.

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