Articles Related to Gingiva
Porphyromonas gingivalis (P. gingivalis) is a primary etiologic agent of generalized aggressive and chronic forms of periodontitis. It releases toxins called ‘gingipains’.Gingipains, (Arginine-and Lysine-specific cysteine proteinases) are proteases that are critical virulence factors in progression of periodontitis and degradation of cytokines expressed during inflammation. HRgpA and RgpB (products of two distinct but related genes) induce vascular permeability by activation of the kallikrein/kinin pathway and activating the blood coagulation system which in turn induces gingival crevicular fluid production and progression of inflammation leading to alveolar bone loss.
This study aimed to determine whether a relationship exists between gingival stimulation and the levels of leptin, ghrelin, insulin and glucose, which are important regulators of energy homeostasis. Blood samples for ghrelin, leptin, glucose and insulin were taken from 15 male volunteers (mean age 25.5±2.3 years; mean body mass index 24.4±2.79 kg/m2), who did not brush their teeth for one day, after a 12 h-long overnight fasting and before standard breakfast (0 min) and thereafter at 30, 60, 120 and 180 min after breakfast. After toothbrushing after dinner and after a 12 h-long overnight fasting, blood samples were taken again before standard breakfast (0 min) and then after at the same time points following tooth brushing.A significant reduction was found in the leptin levels measured at 0, 30, 60, 120 and 180 min after tooth brushing (p < 0.005). The ghrelin levels also declined at these time points but were significant at 0, 30 and 120 min (p < 0.05). Despite the reduced insulin levels at 120 and 180 min after tooth brushing (p < 0.05), no significant change was observed in the glucose levels.
Atypical Granulomatous Lesion of Gingiva: A Case Report on Rare Manifestation of Tuberculosis in Oral Cavity
Primary tuberculosis lesion in oral cavity is a rare clinical entity. We report a case of gingival tuberculosis manifested as chronic ulceration with pus discharge.
Replacement of Missing Lateral Incisor Using A Zirconium Resin-Bonded Fixed Partial Denture: A Clinical Report
This clinical report describes the treatment of a 22-year-old female patient with maxillary lateral incisor agenesis. All-ceramic resin-bonded fixed partial dentures (RBFPD) were selected as the most conservative and esthetic treatment option.
Cleft lip is a common craniofacial anomaly. Median cleft lip is a midline vertical cleft through the upper lip. Of all the types of clefts, minimal Median cleft of the upper lip is a very rare craniofacial anomaly.
Mesenchymal stem cells (MSCs) have been found in almost all tissues and due to their regenerative properties represent promising tools in cell-based therapy. Role of MSCs in tissue repair is strongly governed by their interplay with immune cells and regulating factors.
Porphyromonas gingivalis is an anerobic, gram negative, bacterium which is a natural inhabitant of oral microbiome. Under unhealthy oral hygiene conditions the bacterium becomes highly destructive (photobiont) and leads to periodontitis (inflammation of periodontium).
Periodontal disease is a major oral health problem, in which specific species of bacteria play an important role in its progressing and severity. Because chronic periodontitis is believed to be asymptomatic in its initial stages, it has been suggested that individuals may be unaware of their clinical periodontal status [1-3] and underestimate what treatments are required, as judged by dental professionals .
Good oral hygiene protects against oral diseases such as caries and gum infections. Twice daily tooth brushing with fluoride pastes and flossing are recommended to keep mouth clean and reduce plaque bacterial growth. Poor access to oral cleaning material and dental care services expose children from poor backgrounds to oral diseases.