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Articles Related to Heart Rate

Effects of Gabapentin Enacarbil on Cortical Arousals, Heart Rate, Blood Pressure and Anterior Tibialis EMG Responses Associated with PLMs in Restless Legs Syndrome

Objective: This study was conducted to investigate the effects of gabapentin enacarbil (GEn) on sleep EEG, heart rate (HR), blood presssure, anterior tibialis EMG activity (PLMs power) and subjective complaints in subjects with moderate to severe RLS and disturbed sleep. Methods: This was a single site, single-blind, placebo run-in, fixed dose single group polysomnography (PSG) study. Eligible subjects (age 24-66 years) were treated with placebo for one week and GEn (600 mg/day) for 4 weeks. Two in-laboratory PSGs were collected for adaptation and baseline at the end of the placebo run-in period and for re-adaptation and efficacy assessment at the end of the 4-week treatment period. The primary endpoint was the difference in PSG derived cortical arousal intensity (arousal scale, 0-9) associated with PLMs between 4 weeks of treatment with GEn and placebo. Secondary endpoints included changes in HR responses (ΔHR), nocturnal systolic blood pressure (SBP) changes (>10 mmHg) secondary to PLMs and PLMs power. Other PSG and subjective measures were assessed. Results: Of 20 subjects enrolled, 18 completed the study. Subjects treated with GEn did not show significant improvements in cortical arousal intensity and ΔHR. However, subjects showed reduced PLMs power (p= 0.013) and associated reductions in nocturnal SBP per hour of sleep (p= 0.041) GEn showed significant improvement in other PSG parameters and subjective endpoints. Conclusion: The data suggests that GEn reduces the frequency and power of PLMs and the corresponding SBP changes in subjects with RLS. Despite reducing the total number of PLM associated arousals and nocturnal HR, the study did not demonstrate consistent effects of GEn on cortical arousal intensity and corresponding HR changes associated with PLMs. Clinical Trial Registration: ClinicalTrials.gov identifier: NCT02424695
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Assessment of Autonomic Function in Subjects Practicing Yoga Using Spectral Analysis and Approximate Entropy Method

Autonomic nervous system involvement in subjects practicing Yoga has rarely been studied and has shown conflicting results. Our main purpose was to assess the effect of Yoga on autonomic function of group of subjects practicing Yoga regularly in comparison with another group with normal control subjects by measuring the frequency gain response of the two groups. Other aim of this study was to determine wither the duration of Yoga practicing correlated with measures of heart rate variability signal (HRV) using approximate entropy index (ApEn).
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Hemodynamic and Autonomic Reactivity to Mental and Physical Stress in Lean, Overweight and Obese Subjects

There could be progressive changes in hemodynamic and autonomic parameters causing cardiovascular damage from lean to morbid obesity. We aim to study resting and reactivity of hemodynamic and autonomic parameters to physical and mental stress in lean, overweight and obese subjects of the Oman Family Study (OFS).
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Surface ECG Markers may Predict Impending Atrial Fibrillation after Cardiac Surgery

Postoperative atrial fibrillation (POAF) is a common and dangerous complication following cardiac surgery.
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Could Non-Linear Heart Rate Variability Analysis of Short RR Intervals Series Give Clinically Valuable Information in Heart Disease?

New analytic methods based on nonlinear system theory have been developed to characterize the nonlinear features in HR dynamics. It is known from long time series (24h ECG recordings) that patients with chronic heart failure or stable coronary heart disease have altered fractal organization in heartbeat dynamics. During such long-time series, many confounding could limit the assessment of autonomic functions.
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Anti-Inflammatory and Anti-Arthritic Efficacy and Safety of Purified Shilajit in Moderately Arthritic Dogs

The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion).
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Heart Rate Variability and Occupational Stress: Future Directions

Statistics across industrialised societies show that occupational stress results in social and financial costs for individuals, organisations, and economies. Occupational stress is prevalent in many different forms, for example, work intensification, dissatisfaction with current work schedules, feelings of job insecurity, more work being done at odd hours, the spread of new information and communication technologies, and long hours becoming more common.
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Editorial Board Members Related to Heart Rate

Annapaola Zito

Professor
Cardiovascular Diseases Section
University of Bari
Italy

Rajajeyakumar Manivel

Assistant Professor
Department of Physiology
Chennai Medical College Hospital & Research Centre (SRM Group)
Irungalur, Trichy, Tamilnadu
India

Cameron Newton

Associate Professor
School of Management
Queensland University of Technology
Australia
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