Articles Related to High Performance Liquid Chromatography
Estimation of Beta-Lactam Antibiotics-Serum Albumin Conjugated Proteins by High Performance Liquid Chromatography with Ultraviolet Detector
β-lactam antibiotics represented the oldest class of antibiotics used in the treatment of infections in a human being, livestock, and aquaculture. Drugs residues in the edible tissues or foodstuffs of animal pose a potential threat to human health. At present, extensive antibiotic-resistant strains are now being detected and the development of antibiotic-resistant strains of epidemic and zoonotic pathogens is a major concern. Therefore, the purpose of this study was to estimate the extent of β-lactam antibiotics-HSA/BSA conjugations via three conjugation methods by using high-performance liquid chromatography (HPLC) with ultraviolet (UV) detector. We wish that the technique will be applied to preliminarily detect the residues of β-lactam antibiotics may persist in edible tissues or foodstuffs in the livestock and aquaculture farms in clinical.
Hemoglobin A2 (Hb A2) is a minor component of the hemoglobin present in normal adult red blood cells, accounting for 1.5-3.5% of the total hemoglobin in healthy individuals.
A One-Year Hospital Based Prospective Study of Sickle Cell Disease from One Capital Area of Kuwait by HPLC
Haemoglobinopathies are inherited disorders of haemoglobin synthesis that are responsible for significant morbidity and mortality all over the world.
Relative Bioavailability of Ciprofloxacin Doses (750 and 1000) mg in Healthy Male Volunteers by Using HPLC Method
A new, stable and accurate high performance liquid chromatography ultraviolet spectrophotometric method for quantitation of Ciprofloxacin in human plasma was developed and validated.
Reduction of Bitterness and Enhancing Palatability of Cetirizine Oral Liquid Dosage Forms by Cyclodextrins
The aim of this manuscript is to study cyclodextrins (CDs) as a potential excipient to suppress bitterness and enhance palatability of pediatric liquid preparations for Cetirizine, an extremely bitter drug. Natural α, β and γ CDs; and β CD derivatives such as hydroxyl propyl (HP), randomly methylated (RM) and sulfobutyl ether (SBE) β-CDs were screened in different molar ratios of 1:1, 1:2 and 1:3 for their inhibition of the extremely bitter taste of Cetirizine using the human gustatory sensation test.
Capsaicin, an active ingredient of Capsicum fruit, is currently undergoing “revival” in the clinical management of pain. However, the choice of its formulation is rather limited to the use of “old-fashioned” tinctures and recently the patches. In an attempt to improve the therapeutic outcome and develop its skin-friendly formulation, we prepared the vesicle-based drug delivery system with capsaicin.