Articles Related to Hyperlipidemia
The experiment was conducted to investigate the effect of induced hyperlipidemia in SD rats fed with high fat diet (HFD) for 7 weeks on blood lipid profile and possible pathological changes in liver, stomach, intestine, heart, spleen, lung and kidney. There were significant differences in most rats which induced hyperlipidemia throughout the experimental period with the blood lipid levels and histopathology.
The Association Between Strength, Balance and Physical Function with the Body Mass Index in Dyslipidemia
The coexistence of chronic diseases has led to greater negativity in patients than the negativity of diseases individually speaking. The aim of this study was to investigate the effects of the body mass index on metabolic profile, isometric and isokinetic muscle strength, static and dynamic balance, and anaerobic capacity in dyslipidemia patients, as well as to emphasize what exercises should be recommended for recovering the experienced functional loss of the patients. Forty five patients (26 women, 19 men) between 40 and 75 years of age and who were newly diagnosed as dyslipidemia were enrolled into this study. The patients were divided into two groups according to their body mass indexes (BMI): group 1 (n:18) or those whose BMI was lower than 25 kg/m2, and group 2 (n:27) or those whose BMI was higher than 30 kg/m2. Biochemical blood sampling was done. The Get Up and Go, single leg stance, anaerobic capacity, and isometric as well as isokinetic muscle strength tests were performed in order to evaluate functional capacities. There were no statistically significant differences shown at gender distribution, age, or height (p>0.05) between groups. The weight and BMI’s between the groups were statistically significantly different (p<0.05). The fasting glucose levels and triglyceride levels of group 2 was statistically significantly higher than group 1 (p<0.05), whereas other biochemical parameters showed no differences (p>0.05). The static balance tests results between groups have shown no statistically significant differences (p<0.05); however the dynamic balance test results for group 2 was statistically significantly worse than those of group 1 (p<0.05). The parameters of the results of the anaerobic testing, alongside those of the isometric and isokinetic testing for group 1 patients were statistically significantly higher than those of group 2 (p<0.05). Obesity negatively affects dyslipidemic patients’ metabolic and functional capacities. An exercise program for dyslipidemic patients with a high BMI should include strengthening and balance as well as dynamic balance exercises in order to positively influence both their metabolic profiles and functional status.
Non-arteritic anterior ischemic optic neuropathy (NAION) is an entity that is caused by circulatory insufficiency which affects the proximal portion of the optic nerve. NAION is characterized by the following triad: abrupt and painless loss of vision, optic disc smelling and nerve fiber bundle defects in the visual field of the affected eye.
Drug Tolerability and Outcomes in Kidney Transplant Recipients Treated with Two Formulations of Mycophenolic Acid
Mycophenolic Acid (MPA) is one of the most widely used immunosuppressive agents in kidney transplantation. This study was designed to compare the safety, tolerability and efficacy of two formulations of mycophenolic acid, Mycophenolate Mofetil (MMF) and Enteric-Coated Mycophenolate Sodium (EC-MPS), in renal transplant recipients.