Articles Related to ICS

Lung ultrasound (LUS) is reliable in detecting and quantifying of pulmonary congestion in hemodialysis (HD) patients. Pulmonary congestion holds a negative prognostic value in HD patients even when it is asymptomatic. The pathophysiology of pulmonary congestion in HD is complex and includes volume and non-volume dependant factors. We examined the impact of different inter-dialytic intervals on pulmonary congestion by studying its dynamics using lung ultrasou

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The use of surface electromyography (sEMG) signals for clinical diagnosis is well appreciated in the medical field. However, the use of sEMG signals for the control of powered prosthetic limbs is still regarded as a futuristic idea. Past and present studies have focused more on the upper limb (hand) as compared to the lower limb (leg). The challenges associated with the controlling leg movement include designing for both balance and locomotion. After amputation, the muscle orientation and alignments on the residual stump changes as some of the anatomical landmarks are changed during surgical procedure. To achieve locomotion, some amputees, generally from third-world nations, use passive mechanical prosthetic limbs with a fixed ankle.

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In order to analyze denaturation, we take into account a mapping from the finite temperature phase transition onto a zero temperature quantum phase transition caused by a quench, where the control parameter is the torsion-associated magnetic field and the quench duration handles the temperature effect

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Shin Onodera, Motomi Ishibe (2023) Outcomes Following Debridement, Antibiotics, and Implant Retention with the Exchange of Modular Components in Hip Periprosthetic Joint Infections. J Orthop Physiother 6(1): 101

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Justificative: This trial was conducted in order to register a new generic product of Rivaroxaban. Objective: To evaluate the bioequivalence of rivaroxaban formulations manufactured by Eurofarma Laboratórios S/A and the reference drug, Xarelto (Bayer) under fasting and fed conditions. Methods: Three randomized, open label, balanced, 2 treatments, 4 periods, 2 sequences, single dose, full replicate, crossover studies in 48 healthy adult human subjects under fed and fasting conditions for rivaroxaban 10 mg and 20 mg. Rivaroxaban concentrations in plasma were determined using a validated HPLC-MS/MS method.

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Prostate cancer (Pca) is the second most prevalent malignant neoplasia in man, just after non-melanoma skin cancer. Today, prostate biopsy for tissue sampling is still the gold standard for its diagnosis. However, new generation imaging exam has been used in several clinical scenarios. Yet, positron emission tomography (PET) that targets a specific transmembrane protein on prostatic cells

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Large numbers of nations are associated with utilization of anti-toxins regardless of remedy (OTC medications). This DDD/ ATC value contributes to improved antibiotic use quality. The principal objective is to direct improvement of sane medication use of strategies and to give a standard technique for information for future evaluation.

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Allergic bronchopulmonary aspergillosis (ABPA) is an idiopathic inflammatory disease of the lung, characterized by an allergic inflammatory response to colonization of the airways by Aspergillus fumigatus or other fungi. Untreated or inadequatetreatment may lead to poor outcome in patients. Raised level of serum IgE of more than 1000 IU/ML have been considered as one if theimportant diagnostic criteria for ABPA, however relation of serum IgE withs severity ofdiseases is lacking. This study was conducted to find out level of serum IgE in patients ofABPA and to find out corelation of Serum IgE with duration of symptoms and diseasesseverity.

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This study was conducted to compare the bioavailability of two tablet formulations containing 200 mg Lacosamide (one Lacosamide 200 mg film-coated tablet marketed in Italy as Ollat®, one Vimpat® coated tablet). 20 healthy subjects were enrolled in a single-center, randomized, single-dose, laboratory-blinded, 2-period, 2-sequence, crossover study, with a minimum washout period of 7 days. All the 20 subjects completed the study. Plasma samples were collected up to 72.0 hours post-dosing. Lacosamide levels were determined using a validated high-performance liquid chromatography with tandem mass spectrometry (HPLC/MS/MS) method

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Stress of the endoplasmic reticulum (ER) is induced by the accumulation of misfolded proteins in this organelle. It can be triggered by biotic and abiotic stress (particularly heat), but also by chemical treatments (such as DTT and tunicamycin) at a laboratory scale. To respond to this stress, various cellular mechanisms are involved, including the highly conserved protein repair pathway, the UPR (Unfolded Protein Response). This pathway aims to restore protein homeostasis in cells. In cereals, seed storage proteins (SSP) represent one of the characteristics that determine grain quality and are of great interest to agriculture. Unlike dicots, the dynamics of the UPR induction pathway in monocots are poorly documented in the literature.

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Background and Purpose: Ischemic stroke is a treatable medical emergency. The diagnosis of stroke is mainly clinical and not always so obvious. Intravenous thrombolysis treatment with altepase IV and endovascular treatment have been proved as fist-line beneficial options for eligible patients who have acute ischemic stroke. However, approximately 30% of patients who experience an acute neurological deficit compatible with ischemic stroke fall into the category of "stroke mimics"

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Immune-checkpoint inhibitors (ICI) have provided groundbreaking advancements for a variety of malignancies. It has been of recent interest to identify predictive indicators of response to improve cancer management using immunotherapy. The intestinal microbiome has been recognized as a potential predictor of ICI anti- tumor activity. Antibiotics reduce diversity the overall composition of the gut microbiota, with effects seen as quickly as in a single day. Post-antibiotic dysbiosis recovery varies depending on type and duration of exposure. Preclinical studies in mice with advanced cancer treated with broad spectrum antibiotics have been associated with resistance to ICI treatment.

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The study reports on improved order selection ergonomics, feedback delivery, productivity, and worker satisfaction by replacing a wireless handheld device system with a voice feedback system. ‘Order selectors’ at a dairy manufacturing plant are tasked with selecting dairy products for store orders (e.g. grocery stores, convenience stores). In the new voice feedback system, workers listened to instructions via a headset and spoke directly into a microphone, receiving immediate voice feedback.

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The European Association of Urology currently recommends partial nephrectomy as the preferred management for localised cT1 renal tumours, irrespective of surgical approach. With the advent of robotic assisted partial nephrectomy, there is growing evidence that warm ischaemia time may be reduced compared to the traditional laparoscopic approach.

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The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.

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The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.

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In this paper, we report on the synthesis of BaTiO3 nanowires via the anodic aluminum oxide template method. To fill in the precursors of BaTiO3 into anodic aluminum oxide templates, the vacuum and drop loading method developed in our previous study was used. Ba(CH3COO)2 (barium acetate) and C12H28O4Ti (tetraisopropyl orthotitanate) were used as Ba and Ti sources, respectively. Anodic aluminum oxide membranes with the through-hole diameter of ~200 nm were used as the template for BaTiO3 nanowires.

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