Articles Related to IH

The BDNF/TrkB signaling is a robust regulatory feature of neuronal cells that promotes survival, differentiation, and proliferation in a variety of cell types and animal models for neurodegenerative diseases. The activation of TrkB by BDNF in clinical trials is accompanied by remarkable side effects and appears to be challenging due to BDNF's adverse molecular profile

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The fruit of Crataegus dahurica Koehne ex C.K. Schneid is an edible wild fruit and herb for the treatment of various diseases. However, few studies were conducted to search the chemical constituents of the edible herb. In the present study, a new glycoglycerolipid (1), together with ten known compounds, 2-oxo pomolic acid (2), cecropiacic acid (3), nikoenoside (4), garcimangosone D (5), ampelopsisionoside (6), saussureosides B (7), 6-O-[(2E, 6S)-2, 6-dimethyl-6-hydroxy-2, 7-octadienoyl]-α-D-glucopyranoside (8), 6-O-[(2E, 6S)-2, 6-dimethyl6-hydroxy-2, 7-octadienoyl]-β-D-glucopyranoside (9), betulalbuside A (10), quercetin (11), were isolated from the fruits of C. dahurica with various chromatographic techniques.

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Most forensic investigations are done based on the forensic expert’s level of expertise.

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This paper explores the emerging role of the private sector and public-private partnerships for e-waste management in the developing world. We use a combination of two conceptual frameworks, the triple bottom line approach and the sustainable livelihoods approach, to analyze the case study of the Extended Producer Responsibility (EPR) programme in Nigeria, which was launched in 2016. The sustainable livelihoods approach has been adopted in international development for over two decades, but so far it has not been applied for inclusion of informal sector workers in e-waste. Our findings illustrate how the financial and environmental bottom lines have already received considerable attention during the development of the Nigerian EPR programme, but that the social elements, in particular informal sector inclusion, have received less attention. Consequently, based on proven practices of the sustainable livelihoods approach, this paper identifies opportunities and provides recommendations as to how the international and national private sector players and government agencies involved in Nigeria’s e-waste EPR programme can establish a social engagement model to support inclusion of the informal sector. This model would not only help meet the financial and environmental bottom lines, but also address the social bottom line to improve livelihood outcomes for informal e-waste recyclers.

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To evaluate the value and safety of labetalol in comparison to Alfa methyldopa in treatment of pregnant women with pregnancy-induced hypertension (PIH). 264 patients with PIH were randomly distributed to take either methyldopa (group 1) labetalol (group 2). or Intake of medications with respect to Age, gravidity, Blood Pressure measurement, albumin in urine measurement Levels, Side Effects, dose of the drug, increasing duration of pregnancy, mode of delivery, Perinatal safety and APGAR scores were studied. The statistical level of significance was taken at P<0.05.

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Preeclampsia is clinically defined by hypertension and proteinuria, with or without pathologic edema that occurs after 20 weeks’ gestation, but can also present up to 4-6 weeks post-partum. Worldwide, incidence of preeclampsia is 5-14 percent of all pregnancies, while severe preeclampsia can develop to about 25 percent of all cases of preeclampsia.

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A comparative study on the proximate, mineral amino acid and anti nutritional compositions of sweet and bitter cassava varieties was done to ascertain the nutritional quality and safety after 72 h of fermentation for garri production.

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Inhibiting multiple pathways/targets with combination drug therapies is widely used to maximize therapeutic benefit in many diseases. Therapeutic success can often be improved by concurrently and/or sequentially inhibiting multiple pathways/targets by combining drugs with different mechanisms of action.

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In the analysis of competing risks data, it is common that the exact cause of failure for certain study subjects is missing. This problem of missing failure type may be due to inadequacy in the diagnostic mechanism or reluctance to report the exact cause of failure.

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Lip cancer is relatively common, despite the progress seen recently in Morocco in terms of labial-jugal cancer reconstructions. Lip cancer is often seen in advanced stages and poses management problems.

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Violent offenders are individuals who are incarcerated due to any criminal charge for a violent offence against another individual-armed robbery, murder, attempted murder, kidnapping, assault which results in bodily harm and forcible confinement.

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Cardiac myxomas are a potential source of emboli to the brain and elsewhere in the vascular tree. Myxomas are the most common benign primary cardiac tumor in adults. The commonest location of cardiac myxomas is in the left atrium followed by the right atrium and the remainder develops in the ventricles and rarely in the heart valves.

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The Novel, simple, sensitive, rapid, accurate and economical and reliable First derivative spectroscopic method has been developed for synthetic mixture of Dapagliflozin (DAPA) and Metformin hydrochloride (MET).

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A monoclonal antibody (Mab) designated as GHR106 was generated against the extracellular domain (N1-29 synthetic peptide) of human gonadotropin releasing hormone (GnRH) receptor. It is a first-in-class GnRH analog and can serve as a drug candidate for potential applications in the treatment of human cancers and/or fertility regulations.

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A new, stable and accurate high performance liquid chromatography ultraviolet spectrophotometric method for quantitation of Ciprofloxacin in human plasma was developed and validated.

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