Articles Related to ISS

The paper will be discussed the forthcoming natural and manmade catastrophic events. One day which may affect our Natural Eco – System and its existing Air – Environments’ Climatic Weather Aviation Meteorological Challenges Changing Conditions/ Occurrences, which are abruptly degrading air quality index (AQI) day by day, due to the generation of the Contaminated/ Polluted Constituents/ Black Carbon Soot Particles Emission in the form of solid, liquid and gaseous substances Whole Around the GLOBE at Local, Regional and Worldwide Scale. Detailed project Kurkuti – Ghamsali – Niti Highway explored for civil engineering highway construction may influence on various types of meteorological weather parameters/ proceedings during the construction highways’ road network. The promotion of cleaner, climate – friendly technologies and improved environmental management practices for enhanced livelihood sustainability and fostering resilience requires resources, which are fast – tracking speedily and all have strong interlinks/ connections through highway roads networks in civil engineering/ buildings/ industries producing anthropogenic substance in natural eco – system and its environment as depicted in Figure 1: Scheme Accomplishment Purposes and Judgment Creation Effort – Lifespan Progression…!!! Through Technology Transmission (T3 Formula…!!)

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Background: The smell in a hospital is an amalgam of smells, emanating from varied sources. But primarily the smell is from the strong cleaning agents used in corridors, including phenyl and bleaching powder, etc. Chemicals that trigger odors may cause health effects. A strong urine odor is also responsible for foul smells in hospitals and other public facilities. Strong odors may cause some people to feel a burning sensation, leading to coughing, wheezing, or other breathing problems.

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Superficial CD34-positive fibroblastic tumor is an infrequent soft-tissue tumor characterized by a lesion located in the subcutaneous fascia without affecting the soft or deep muscle planes. Its incidence is unknown; therefore, it represents a diagnostic challenge for both the surgical oncologist and pathologist. Given its high risk of local recurrence, extensive surgical resection is the recommended treatment modality. This is the first report of this rare entity in Latin-America.

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Dengue fever remains an annual worldwide threat to human health, even though Aedes eradication programs based on the typical route of mosquito- borne transmission have successfully controlled dengue epidemics to a considerable extent. Interestingly, most cases of dengue infection in humans reported in the tropical regions of Asia, Oceania, Africa, and the Americas are due to horizontal transmission. This suggests contribution of atypical transmission routes to continuous infections.

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Abstract Background: Clinical studies demonstrated the efficacy of therapies based on the autologous grafting of adult mesenchymal stem cells to accelerate the healing and regenerative processes of the skin and mesenchymal tissues therefore, this is considered a valuable approach in the aesthetic rejuvenation treatment to give volume restoration and skin regeneration effects. Objective: The aim of this project consists of the evaluation of the cell viability of adipose tissue (AT) harvested using the Superficial Enhanced Fluid Fat Injection (SEFFI) procedure standardized by the Authors (AG, FPB). The harvesting procedure was performed using two different cannulas having 0.8 mm and 1 mm side-port holes, respectively. Cells phenotype and ability to adhere to the plastic surface have been analysed. The results have been compared to those recorded in adipose tissue harvested using a liposuction system and processed with enzymatic digestion (collagenase). Methods: This study was performed on adipose tissues harvested from 7 patients (6 females and 1 male) with an average age of 48.5 years with two different techniques and three different cannulas. We compared the cell vitality of every sample at T0 and T72. Moreover, the samples were analysed to determine the phenotype: cells were incubated with antibodies anti human against CD90-FITC, CD73-PeCy7, CD44-PE, CD31-PECy5, CD235a- PECy7, CD34-FITC, CD45-FITC and CD146-FITC and read using the flow cytometer s3e Cell Sorter, BioRad. Results were analysed using the software Flow Jo.

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A majority of Carbon-dioxide including smaller amounts of methane and nitrous are emitted from the consumption of fossil fuels around the world to meet the sustainable development goals and global prosperity. Studies have shown that the increase in greenhouse gases has negative effects on human health, and the environment around us. Emissions from the consumption of fossil fuels in factories and industries either to produce electricity or transport people, goods and services cause the release of CO2 and other pollutants into the atmosphere. The majority of industrial energy is supplied by nonrenewable energy resources, which mainly consist of fossil fuels. Currently, fossil fuels are the main source of energy and are concentrated in some regions of the world, therefore direct contamination occurs in areas where they are stored or processed. A majority of electricity consumed by cities and countries across the world is produced from fossil fuels, which accounts for the highest percentage of overall CO2 production in that particular country. People will share the common global environmental problems, either it is local or regional, hence immediate actions are needed to tackle problems at national and regional and global levels. Fortunately, with the advent of new technologies and intervention strategies, it is possible to reduce pollution and reduce the rate of rising global temperature that might result in better economy and ecological systems as well as providing sustainable energy resources. In this research the data on nonrenewable energy sources, fossil fuel reserves in different regions, production and consumption rate of fossils have been identified and reviewed. Additionally, mathematical calculation has been done to find the carbon dioxide emission amounts, both international and national legislations as well as further recommendations have been provided to reduce or prevent emissions.

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Non-exhaust road transport emissions, particularly tyre-pavement abrasion, contribute to poor air quality. This original work is on particle emissions caused by tyre-pavement abrasion in real driving conditions in urban, suburban and motorway areas. The collected data were analyzed according to the size, the number and chemical identification. Multivariate analysis provided clusters of size and chemical elements. Results showed the predominant particles (diameter φ < 1 μm and φ ε]1-2 μm]) for urban and suburban experiments, and ]1- 3 μm] on motorways. A confirmed shift phenomenon at the close-to-the-source showed particles of large sizes [5- 10 μm]. The obtained clusters were: 1. Aluminosilicate, iron compounds, silicate free of aluminum (70%). 2. Ferrosilicon, silica, compounds of calcium, manganese, iron oxide, compounds of aluminum, sulfur, copper and zinc (29%). 3. A mix of various traces (1%). This paper will contribute to the development of new green technologies dedicated to improving sustainable road transport.

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Data on illness in preterm infants due to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is limited. Duration of viral shedding and treatment options including use of dexamethasone to treat SARS-CoV-2 pneumonia in preterm newborns are scarce and not-well reported. We are reporting SARS-COV-2 positive sick preterm twins vertically infected from SARS-COV-2 positive unvaccinated mother. Twin B initially tested negative at 24 & 48 hours of life (HOL) but subsequently tested positive at 72 HOL and developed SARS-COV-2 pneumonia and required a longer duration of respiratory support. We treated her with 10 days of dexamethasone and noted a good clinical response. To our knowledge, we are first to report the use dexamethasone in a premature newborn with SARS-COV-2 pneumonia. Additionally, the duration of viral shedding in both Twin A and Twin B was between 4-5 weeks.

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Traditionally, a typical phase II trial has been conducted using a single-arm design recruiting patients only to the experimental therapy to be compared with a historical control. Due to a small sample size and heterogeneity of patient population, the patient characteristics of the patients in a new phase II trial is often different from that of the selected historical control, so that the single-arm phase II trial may lead to biased conclusions. A randomized phase II trial can resolve such problems by randomizing patients between an experimental arm and a control arm. We propose a software package for designing and analyzing randomized phase II trials. We develop a user-friendly Java software that will help us find optimal two-stage phase II trial designs. Although the programs accommodate trial designs based on various statistical methods and different types of early stopping rules, the main part of our paper is focused on randomized phase II trials based on Fisher’s exact test with futility and superiority early stopping values. If users enter input parameter values, the software generates a graphical output displaying all efficient two-stage designs. Minimax, optimal, and admissible designs are highlighted as good designs, but users can select any of the displayed designs. When the circle representing a design is clicked, all the specifics of the selected design are displayed. Fisher’s test is an exact method whose critical values depend on the total number of responders from two arms. So, the computations required to search for optimal randomized multi-stage phase II trial designs based on Fisher’s exact test is very heavy. By using efficient algorithms, our software provides output at almost real time speed

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Several factors have been identified as contributing to medical errors such as labels, appearance, and location of ampules. In this paper, inadvertent intrathecal Injection of tranexamic acid has resulted from similarities in appearance between tranexamic acid and heavy bupivacaine 0.5% ampoules. The patient experienced severe itching in the gluteal region followed by generalized myoclonic seizures after accidental intrathecal administration of tranexamic acid.

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One factor underlying medical errors in “confirmation bias,” the tendency to interpret new evidence as confirmation of one’s existing beliefs or theories. When a medical error occurs, the physician has a moral duty to examine the factors which lead to its occurrence, to discuss these factors with the patient who suffered the error, and to perform their due diligence to prevent the error from occurring again. Restorative Justice is a form of collaborative decisionmaking including all parties involved in a precipitating event, including the perpetrators, victims, and stakeholders. We report on a case in which confirmation bias played a major role in misdiagnosis followed by the application of Restorative Justice principles to address the consequent mistrust between the physician and patient.

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Driving pattern of the given vehicle in a city is represented by the driving cycle which is used by modal models for estimation of vehicular emissions. In this study, a driving cycle was developed for passenger cars in the city of Islamabad. A representative route for city was identified which included parts of highway, arteries, and streets. Speed-time data was collected along the selected route in both peak and off-peak hours. The on-board measurement method was adopted for data collection on highways, whereas on arteritis and streets, chase car method has opted for data collection. The developed cycle showed comparable values of average speed and acceleration with New European Driving Cycle (NEDC), but acceleration and deceleration were observed to be lower. The emission estimation and fuel consumption were calculated by the Comprehensive Modal Emission Model (CMEM) for 4 selected vehicle types. The average emissions for the selected vehicles were 204.4 g CO2/km, 2.3 g CO /km, 0.09 g HCs /km, 0.31 g NOx /km emitted, and 65.7 g of fuel consumed /km. The developed cycle showed higher fuel consumption and CO2 emissions /km traveled than NEDC for all 4 passenger car types. However, HCs, CO, and NOx emissions were lower. The developed driving cycle can be used for estimation of the emissions from passenger cars in the city and this information can be useful for future emission projections and policy making.

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The emissions trading system is an important tool to combat climate change, which uses the “cap and trade” principle to reduce carbon dioxide emissions. This paper first adopts production technology considering carbon emission permit trading and proposes a data envelopment analysis (DEA) model to evaluate carbon emission efficiency of Chinese fire power industry from 2013 to 2017. Further, a new zero sum gains DEA（ZSG-DEA）considering carbon emission permit trading model is proposed based on efficiency principle to adjust the initial allocation of carbon emission permits (considering fairness principle) among regional fire power industries in 2030. The new approach enables us to investigate the carbon emission efficiency and emission permit allocation problem from an emission permit trading perspective. Theoretical analysis show that organizations have higher potential in reducing carbon emissions and greater potential in improving inputs and outputs after introducing emitting permit trading. Empirical results show that the southeastern fire power industries have higher carbon emission efficiencies and permitted emission levels. Under the background of carbon emission permit trading, the allocation level of carbon emissions permit in inefficient areas is limited and given greater responsibility for reducing emissions considering fairness and efficiency principles. This could promote active carbon emissions reduction in various regions so as to realize China’s carbon emissions [1] reduction targets in a faster pace.

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Blastomycosis is known for its propensity to mimic other illnesses, which often leads to incorrect or delayed treatment. Here we present a case report of a patient working in Wisconsin who was misdiagnosed as Tuberculosis since he was an Indian. The patient was not evaluated on endemic grounds for Blastomyces where he was working for couple of years. After he developed skin lesions along with increased shortness of breath, lesions were evaluated which showed large yeast cells resembling Blastomyces. The treating pulmonologist evaluated his occupational history and was revealed with endemicity for Blastomyces.

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Fluoxetine Hydrochloride (FH), a selective serotonin reuptake inhibitor (SSRI) is a drug of choice in depression, obsessive-compulsive disorder (OCD), bulimia nervosa, etc. Though tablet, capsules, oral solution, or syrup are currently available conventional dosage form of FH, modified or immediate-release formulations for fast onset of action is of utmost importance.

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With this special issue of JMSN we are pleased to present significant contributions to a fascinating topic in the field of materials nanostructing, which is the anodization of valve metals. By this treatment porous oxides of controlled geometry can be grown on the respective metal surfaces. To date, aluminum (Al) has been used most often, as confirmed in this special issue where nine out of ten contributions deals with its anodization.

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