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Articles Related to Integra

Bioequivalence Study of Donepezil 10 mg Orally Disintegrating Tablets in Healthy Thai Volunteers Under Fasting Conditions

Donepezil is a potent, selective, noncompetitive and reversible inhibitor of acetylcholinesterase, commonly used for the treatment of Alzheimer’s disease. The form of orally disintegrating tablets (ODTs) is a good alternative dosage form for patients who have a difficulty in swallowing conventional tablets or capsules.
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Bioequivalence Study of Olanzapine 5 mg Orally Disintegrating Tablet Formulations in Healthy Thai Volunteers under Fasting Conditions

A comparative randomized, single dose, two-way crossover, open label study was carried out to assess bioequivalence and tolerability of test (ZOLAN GPO®) and reference (Zyprexa Zydis®) products of olanzapine 5 mg orally disintegrating tablets for interchange ability in the same quality and safety.
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Pharmacokinetics of a 1,000 mg Disintegrating Aspirin Tablet Formulation

Migraine is a global disorder and considerably affecting people`s quality of life. Treatments include nonsteroidal anti-inflammatory drugs-containing medicinal products among whom acetylsalicylic acid-containing Aspirin® has been proven effectively to relief migraine headache. Early treatment is recommended for patients with migraine attacks.
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The Effect of Bundled Interventions on Prevention of Hospital Acquired Clostridium Difficile Infection: An Integrative Review

Hospitalized patients are at an increased risk for acquiring Clostridium Difficile Infection (CDI). Increased virulence of C. difficile strains and increased use of antimicrobials have led to an increase of CDI cases that are more difficult to treat (CDC, 2013). Proper hand hygiene techniques, room cleaning, and equipment cleaning are not consistently being followed by healthcare workers, leading an increased spread of CDI between hospitalized patients. The purpose of this integrative review was to determine the best evidencebased methods to reduce hospital-acquired CDI rates. The evidence reviewed supports the implementation of a multifaceted approach including: (a) proper hand hygiene practices, (b) adequate and appropriate surface cleaning practices, (c) compliance to contact isolation procedures, and (d) strengthening of an existing antimicrobial stewardship committee to reduce hospital-acquired CDI rates.
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Provision of Adolescent-Friendly Sexual and Reproductive Health (SRH) Services Integrated into HIV Treatment and Care

Integration of HIV prevention services into reproductive health, care support and treatment programs can potentially increase the uptake of FP, dual protection and reduce vertical transmission of HIV.
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An Introduction to the Approaches of Novel Drug Delivery Systems for Acquired Immune Deficiency Syndrome (AIDS)

The currently available anti HIV agents have several drawbacks such as short half life, low bioavailability, poor CNS penetration and retention, hepatic first pass metabolism, undesirable side effects and frequent dosing regimen.
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Coverage of Exposed Lower Extremity Bypass Vascular Graft with Integra and NPWT for Limb Salvage

Integra was first used to replace the dermis in third-degree burns to minimize contraction and scarring, its usage had led to better functional and aesthetic results. It acts as a network for dermal reconstruction. Its usage had expanded in trauma and soft tissue defects resulting after cancer excision and other defects with tendons and bone exposure.
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Combating Childhood Obesity with an Integrated School Curriculum

The prevalence of overweight and obesity among US adults is well-documented and lifestyle intervention remains the foundation for all overweight and obesity treatment interventions, even when bariatric surgery is offered. Unfortunately, lifestyle intervention, though clearly a vital part of any obesity treatment, including bariatric surgery, has not been found to be as effective in achieving health benefits as hoped for.
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Orally Disintegrating Tablets: A Short Review

This article summarizes the advantages of orally disintegrating tablets (ODTs) as well as critical issues during evaluation of ODTs such as bioequivalence and challenges and limitations of ODTs and finally present and the future of ODTs. ODTs have received everincreasing demand and the field has become a rapidly growing area in the pharmaceutical industry.
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Evaluation of Luffa Aegyptica Mill Powder: A Novel Superdisintegrant in Delayed Release Tablets

The current research in the field of drug delivery by which pulsatile release can be achieved has been intensified. The objective of the present study was to evaluate Luffa aegyptica mill powder as a novel superdisintegrant in the development of pulsatile drug delivery system (PDDS).
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AIDS: Signs to Management of the Disease

Acquired Immune Deficiency Syndrome (AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV). They get it after being infected with the HIV virus. HIV (human immunodeficiency virus) is a retrovirus that primarily infects components of the immune system.
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Croscarmellose Sodium Efficiency in the Development of a Generic Capsule Formulation of Piroxicam, Comparable Dissolution Profile to the Innovator Product, Feldene

The objective of this study was to evaluate the encapsulation performance of Croscarmellose sodium, a superdisintegrant in a low-dose, poor-solubility drug formulation and the in-vitro dissolution performance of the Piroxicam capsules. Preparation, characterization and evaluation of the effects of the different concentrations of carmellose sodium and the amount of dried starch on in-vitro dissolution of Piroxicam capsules. Piroxicam was chosen for its very low solubility in biological fluids, which result in poor systemic bioavailability after oral administration. Piroxicam can be categorized as Class II drugs according to the Biopharmaceutics Classification System.
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A Reintegration Program for Elderly Prisoners Reduces Reoffending

Harsh sentences have resulted in many prisoners being elderly at the time of their release. However, the longer individuals have been incarcerated and the older they are, the more difficult it may be for them to re-enter free society. We developed a reintegration program to promote their successful adjustment to society and to prevent their reoffending, and evaluated its effectiveness. Participants were 25 older prisoners in Japan; all were homeless and more than 65 years old.
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Feasibility Analysis of Autogenous Tooth-based Bone Graft Material after Guided Bone Regeneration Technique

We set out to determine the possibility of radiographically evaluating the degree of marginal bone loss in humans after functional loading of implants at sites of guided bone regeneration (GBR) with autogenous tooth-based bone graft (ATBBG) material (AutoBT®, Korea Tooth Bank, Seoul, Korea).
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Reduction of Bitterness and Enhancing Palatability of Cetirizine Oral Liquid Dosage Forms by Cyclodextrins

The aim of this manuscript is to study cyclodextrins (CDs) as a potential excipient to suppress bitterness and enhance palatability of pediatric liquid preparations for Cetirizine, an extremely bitter drug. Natural α, β and γ CDs; and β CD derivatives such as hydroxyl propyl (HP), randomly methylated (RM) and sulfobutyl ether (SBE) β-CDs were screened in different molar ratios of 1:1, 1:2 and 1:3 for their inhibition of the extremely bitter taste of Cetirizine using the human gustatory sensation test.
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Anodic Oxidation of Titanium in Sulphuric Acid and Phosphoric Acid Electrolytes

Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.
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Editorial Board Members Related to Integra

Shirley Mcilvenny

Professor
Department of Health and Nutrition
National Institute of Integrative Medicine
Australia

Jian Zhu

Assistant Professor
Department of Biochemistry and Biophysics
University of Rochester Medical Center
United States

ASIF ALI

Assistant Professor
Academy of Scientific & Innovative Research (AcSIR)
India

Yao Olive Li

Assistant Professor
Department of Human Nutrition & Food Science
California State Polytechnic University
United States

RAJNISH S. DAVE

Associate Scientist
Department of Neuroscience
Temple University
United States

Peter L. Bordi

Associate Professor
School of Hospitality Management
Pennsylvania State University
United States

Michael Gibson

Associate Professor
Department of Medicine
Case Western Reserve University
United States

Abdelfattah Y. M. Nour

Professor
Department of Basic Medical Sciences
Purdue University
United States

Frank C. Barone

Professor
Department of Neurology
SUNY Downstate Medical Center
United States

Miklas Scholz

Professor
Water Resources Engineering
Lund University
Sweden
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