Infective endocarditis is most often seen affecting the left side of the heart, with the pulmonary valve being the least frequently involved
valve. The most common organisms responsible for infective endocarditis are Staphylococcus aureus and Streptococcus viridans. Here
we report a rare case of pulmonary valve endocarditis due to Streptococcus pneumoniae, a rare pathogen for this setting. The clinical
features, presentation, and review of the literature are discussed.