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Bioequivalence Evaluation of Two Clopidogrel Immediate Release Tablet Formulations in Healthy Thai Volunteers Under Fasting Conditions

Clopidogrel is used for acute coronary syndrome and prevention of atherothrombotic events. To improve clinical outcomes, patient adherence to treatment is necessary. However, continuous use of branded product may cause economic burden to patients and healthcare system. The Government Pharmaceutical Organization (GPO), Thailand had developed a generic product of clopidogrel to reduce cost of treatment and improve accessibility to medicines for Thai people.
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Relationship between Blood Ethanol Concentration, Ethyl Glucuronide and Ethyl Sulfate and Clinical Signs of Alcohol Intoxication

Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are markers for screening previous alcohol consumption and indicating recent drinking in cases of suspicion of driving under the influence of alcohol.
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Voromonas Pontica Identified by Giemsa Staining and Anti-RhopH3 Protein Reactivity

Culture characteristics, routine staining for light microscopy and feeding behavior of Voromonas pontica Cavalier-Smith (American Type Culture Collection, ATCC 50640), a predatory free-living marine colpodellid, was investigated
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A Comparative Study of Different Blood Alcohol Concentration Effect on Handwriting

Handwriting is a visible speech which is not spoken but written. There are various internal and external factors that might cause variation in handwriting
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Separation and Detection of Monocrotophos by Chromatography Methods in Forensic Samples

Monocrotophos is a extremely hazardous organophosphate insecticide that is extensively used and easily accessible in India.
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Bioequivalence Study of Olanzapine 5 mg Orally Disintegrating Tablet Formulations in Healthy Thai Volunteers under Fasting Conditions

A comparative randomized, single dose, two-way crossover, open label study was carried out to assess bioequivalence and tolerability of test (ZOLAN GPO®) and reference (Zyprexa Zydis®) products of olanzapine 5 mg orally disintegrating tablets for interchange ability in the same quality and safety.
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Determination of N-Butylscopolamine in Human Plasma by Solid-Phase Extraction and UHPLC-ESI-MS/MS: Development, Validation and Application to a Bioequivalence Study

BioequivalenceA sensitive ultra performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS) method for measurements of N-butylscopolamine in plasma was developed and validated. A SPE extraction was proposed for the clean up of plasma and N-butylscopolamine-d9 was added as internal standard. The analyses were carried out using a phenyl column and mobile phase of acetonitrile:
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A Novel Neuroprotective and Antioxidative Efficacy of a Unique Combination of Standardized Huperzia serrata, Convolvulus pluricaulis and Celastrus paniculatus Extracts

Physical and environmental stress in conjunction with hectic lifestyle and unhealthy food habits are the major cause of diverse neurodegenerative disorders. Oxidative neuronal injury and acetylcholine deficiency have a major impact on learning and memory retention. Most of the treatment strategies are based on the improvement of cholinergic function in the brain and one of the emerging therapeutic targets is to enhance the acetylcholine level in the brain. Standardized botanical extracts including Huperzia serrata (1% Huperzine A, CogniUp), Convolvulus pluricaulis (SP) and Celastrus paniculatus (JY) have been demonstrated to attenuate brain function by serving as a natural acetylcholinesterase (AChE) inhibitor.
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Impact of the Biofield Energy Treated Proprietary Novel Formulation on Memory and Cognition Function in Neuronal Cell

The current study was investigated for the in vitro cognitive effect of the Consciousness Energy Healing (The Trivedi Effect®) Treated novel proprietary test formulation in terms of acetylcholinesterase (AChE) inhibition, neuroprotection, and neurite outgrowth assays in two different neuronal cell-lines (SHS-Y5Y and PC-12 Cells). The test formulation divided into two parts; one part was received the Biofield Energy Treatment by Mr. Mahendra Kumar Trivedi and termed as the Biofield Energy Treated sample, while the other part was denoted as the untreated test sample.
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A Study on Chromatography Methods for the Separation and Detection of Certain Benzodiazepine Drug in Forensic Sample

Forensic Scientists are required to identify an ever increasing and more complex assortment of drugs and related compounds.
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Optimization of Pseudomonas aeruginosa for Chlorpyrifos Degradation using Response Surface Methodology

Chlorpyrifos is a hazardous organophosphate pesticide used worldwide thus its biodegradation is need of the time. In the present study 13 bacterial strains were isolated from collected soil samples of different agro climatic regions and out of them one bacterial strain was screened out as potent degrader of Chlorpyrifos on the basis of percentage degradation using high pressure liquid chromatography (HPLC).
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Spontaneous Bruising on the Face, Neck and Chest

Bruises are due to the blood leaking from vessels into the dermis. They usually occur at sites exposed to trauma, mainly the lower limbs, outer hips and arms. Spontaneous bruising (purpura and ecchymoses) restricted to the face, neck and chest are an exception to the rule.
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Preparation and Performance Analysis of High Temperature Resistant and High Strength Alcohol Soluble Phosphate/Phenolic Hybrid Adhesive

A kind of alcohol-soluble phosphate adhesive was prepared by using phosphate solution as raw material. A hybrid high temperature and high strength adhesive was prepared by adding phenolic resin. The wetting condition of water-soluble and alcohol-soluble phosphate adhesive on the surface of hydrophobic material, the composition and mechanical properties of the adhesive were analyzed by means of liquid drop shape analyzer (DSA), X-ray diffraction instrument and universal tensile force machine. The results show that the alcohol-soluble phosphate adhesive has good wetting effect on hydrophobic materials and has excellent high temperature resistance and mechanical properties.
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Tracheobronchopathia Osteochondroplastica: A Case Report

Tracheobronchopathia osteochondroplastica (TOCP) is a rare disease defined by the presence of osteocartilaginous foci in the submucosa, without direct connection to the cartilage structures of the respiratory tree. The disease is usually located in the trachea, sometimes in the bronchi and more rarely in the larynx.
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Kaempferol 3-glucoside from Azadirachta indica

World population up to 80 percent relies on traditional medicine. Currently use of medicinal plant/herbal medicine for treating various disorders and diseases is quickly evolving. Due to their less side effects. Azadirachta indica (Neem) is one such important medicinal plant widely used in ethno traditional medicine for centuries, which is cosmopolitan in distribution and belongs to the family Meliaceae. In India, it is extensively used in several native medical practices.
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Fabrication of Vertical Cu2ZnSnS4 Nanowire Arrays by Two-Step Electroplating Method into Anodic Aluminum Oxide Template

Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.
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Editorial Board Members Related to LC

EHAB SAMIR AZIZ FARAG

Associate Professor
Department of General Anesthesiology
Cleveland Clinic Lerner College of Medicine
United States

Loai Aljerf

Professor
Department of Basic Sciences
Faculty of Dental Medicine
Damascus University
Syria

FRANCISCO FERNANDEZ CAMPOS

Professor Adjuant
Department of Pharmaceutical Technology
University of Barcelona
Spain

Raghu Vannam

Scientist
Olon Ricerca Bioscience LLC
United States

Mirosław Kwiatkowski

AGH University of Science and Technology
Faculty of Energy and Fuels
Poland

Sayed M. Hassan

Senior Research Scientist
University of Georgia
USA

ZAYDE ALCICEK

Associate Professor
Faculty of Marine Sciences and Technology
Canakkale Onsekiz Mart University
Turkey

Osman Balci

Professor
Department of Computer Science
Virginia Polytechnic Institute and State University
United States

Chang Ming Charlie Ma

Professor
Department of Radiation Oncology
Fox Chase Cancer Center
United States
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