Articles Related to LV

Stress of the endoplasmic reticulum (ER) is induced by the accumulation of misfolded proteins in this organelle. It can be triggered by biotic and abiotic stress (particularly heat), but also by chemical treatments (such as DTT and tunicamycin) at a laboratory scale. To respond to this stress, various cellular mechanisms are involved, including the highly conserved protein repair pathway, the UPR (Unfolded Protein Response). This pathway aims to restore protein homeostasis in cells. In cereals, seed storage proteins (SSP) represent one of the characteristics that determine grain quality and are of great interest to agriculture. Unlike dicots, the dynamics of the UPR induction pathway in monocots are poorly documented in the literature.

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The present work aims to study a convenient and environmentally friendly method for the green synth of silver nanoparticles (AgNPs based on lemon juice extract. The biomolecules contained in lemon extract act as self- reducing and stabilizing agents. The optimal solution for the synthesis of AgNPs was determined by varying silver nitrate concentrations. A surface plasmon resonance system identified the synthesized silver nanoparticles by their color change from colorless to dark brown. Silver nanoparticles synthesized were characterized by Uv-visible (UV-Vis) spectroscopy, high-resolution transmission electron microscopy (HR-TEM), and FTIR spectroscopy. As a result of UV-visible spectroscopy, surface plasmon resonance (SPR) can be determine

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Prevention of obstetric trauma from damage to the pelvic floor is not always possible and sacral nerve stimulation (SNS) may be necessary later in life. Sacral nerve stimulation has been a promising innovation in the management of moderate to severe faecal incontinence and following sphincter repair failure. Although the indication spectrum for SNS is expanding, the success of neuromodulation for constipation is limited. Adverse events of SNS requiring reintervention are not common but a long-term successful outcome may depend on interventions for maintenance of the device.

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Blastomycosis is known for its propensity to mimic other illnesses, which often leads to incorrect or delayed treatment. Here we present a case report of a patient working in Wisconsin who was misdiagnosed as Tuberculosis since he was an Indian. The patient was not evaluated on endemic grounds for Blastomyces where he was working for couple of years. After he developed skin lesions along with increased shortness of breath, lesions were evaluated which showed large yeast cells resembling Blastomyces. The treating pulmonologist evaluated his occupational history and was revealed with endemicity for Blastomyces.

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Cryptococcosis caused by Cryptococcus gattii differs from that due to C. neoformans by an increased incidence of cryptococcomas in lung and brain, higher neurological morbidity and slower response to antifungal therapy. A case report of a renal transplant recipient with disseminated and fatal cryptoccocosis is presented. For this patient and for 12 controls, bronchoalveolar lavage fluid levels of IL-10, TNF-α, IL-12p40, CXCL-8 and CXCL-10 were measured. Broth microdilution assay, in accordance with CLSI-M27-A3 document was performed to determine antifungal susceptibility. BAL yielded yeasts when cultured that were identified as C. deuterogattii through biochemical reactions and URA5-RFLP genotype. The strain presented susceptibility to amphotericin B, itraconazole, voriconazole, fluconazole, and ketoconazole. The patient presented significant higher levels of IL-10 (73.22 pg/mL), IFN-γ (257.08 pg/mL), CXCL-8 (161.93 pg/ml) and CXCL-10 (1000.76 pg/mL) than controls. Different from C neoformans, scarce data are available about the immune response in patients with C. deuterogattii infection, especially cytokine profile on BAL.

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Malignant infarction of the middle cerebral artery territory is a serious clinical form with a mortality rate of approximately 80%. Several large studies have demonstrated the effectiveness of decompressive hemicraniectomy in reducing mortality and functional impairment following malignant infarction of the middle cerebral artery. The aim of this work was to assess the mortality and functional prognosis of patients who underwent decompressive hemicraniectomy surgery for malignant infarction of the middle cerebral artery from 2009 to May 2016 at the Regional University Hospital of Besançon.

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Buschke-Lowenstein tumor or giant condyloma acuminata is a rare disorder of the external genitalia, belonging to the group of verrucous carcinomas, and usually affects immunocompromised men. Human Papillomavirus (HPV) 6 and 11 are potentially involved in the pathophysiology. A detailed questioning, a rigorous clinical examination and complementary imaging are important to establish an accurate lesion assessment and an adapted management. Wide surgical excision is the treatment of choice.

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From Jan –2004 to Dec-2004, five patients were referred to the surgical department with a diagnosis of endocarditis refractory to medical therapy. Patients were all male, age ranging 16 years to 28 years with a mean of 22 years. All of the five patients had native valve endocarditis of the tricuspid valve with a history of drug addiction in common. Their presentations included, sepsis, failure and recurrent pulmonary embolism. Three of them had bacterial, while two had fungal infection which was proven after blood cultures. After resuscitation, stabilization and preoperative workup, tricuspid valvectomy was performed on these patients because of the destructive and irreparable nature of the native valve. Fortunately, all had uneventful recovery after surgery. Pre-operatively these patients were treated with antibiotics and antifungals, and continued thereafter for almost 4 to 6 weeks in the post-operative period. Postoperatively there was significant tricuspid regurgitation in a subset of patients who had a follow-up. The Left Ventricular (LV) function remained normal to moderate with a moderate pulmonary artery pressure. These patients were discharged on antibiotics and anti-failure medications as per the GDMT.

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Fluoxetine Hydrochloride (FH), a selective serotonin reuptake inhibitor (SSRI) is a drug of choice in depression, obsessive-compulsive disorder (OCD), bulimia nervosa, etc. Though tablet, capsules, oral solution, or syrup are currently available conventional dosage form of FH, modified or immediate-release formulations for fast onset of action is of utmost importance.

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Considering high demand of exploring clean and sustainable source of energy worldwide, biomass derived green bioenergy has tremendous potential. Amongst all possible ways of biomass processing to derive bio-fuels, the biomass pyrolysis is highly preferred thermochemical process that converts the biomass to bio-oil. In our present work, the noncatalytic pyrolysis of ligno-cellulosic biomass samples (sawdust, rice straw and cotton stalk) was successfully carried out using in-house developed fixed bed pyrolytic reactor.

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Neonatal management of severe quadricuspid truncal valve insufficiency is very challenging with high risk of postoperative mortality. Aortic valve reconstruction is the unique rescue and should be consider and previously planned in case of truncal valvuloplasty failure. Many extracardiac malformations can be associated with truncus arteriosus, therefore a cardiac and chest computed tomography scan must be performed before the elective surgical repair.

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The concept of an effective cognitive boosting nootropic supplement is gaining traction with consumers, neuroscientists and regulators alike and it is therefore unsurprising that scientifically validated Nootropics are highly prized. New research demonstrates edible crops could be useful sources to mine for new nootropics; plant extracts enriched with an array of cognitive enhancing metabolites. There is merit in investigating these plant species. Metadata has identifies consuming specific fruit and vegetables positively affects cognitive function; therefore these same edible crop plants present as opportunities for developing nootropic formulations. This hypothesis is supported by positive data obtained through clinical testing [e.g. extracts of tomato (Solanum lycopersicum), herbs from the Genus Salvia, cocoa (Theobroma), tea (Camellia sinensisor) and coffee (Coffea Arabica). This review will discuss clinically tested cognitive enhancers derived from edible crop species and discuss their use alongside other classes of nootropics.

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Extramedullary plasmacytoma (EMP), characterized by infiltration of malignant plasmablastic clones outside the bone marrow in absence of multiple myeloma.

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Multiple primary parotid gland tumors are rare, accounting for 1.7-5% of all parotid neoplasms, and the occurrence of bilateral parotid gland tumors is even lower (1.3-3.5%). These tumors can be synchronous or metachronous and the most common histologic type of bilateral parotid gland tumors is Warthin tumor (79.2-90%). Combined benign and malignant lesions and bilateral neoplasms of different histologic types are even less frequently found.

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Stool impaction is an ailment resulted from chronic constipation which commonly found in the elderly population. It causes wide range of potential complications if not promptly diagnosed and treated. These complications doubled when elder people experience other comorbidities. A case of an 80 years old lady with advanced dementia, bedridden and non-communicating is presented for clinical study. This patient who was presented with abdominal distention and changes in her mental status was found to have stool impaction based on the clinical and radiological test conducted to her.

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With this special issue of JMSN we are pleased to present significant contributions to a fascinating topic in the field of materials nanostructing, which is the anodization of valve metals. By this treatment porous oxides of controlled geometry can be grown on the respective metal surfaces. To date, aluminum (Al) has been used most often, as confirmed in this special issue where nine out of ten contributions deals with its anodization.

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The results are presented of obtaining anodic aluminum oxide with an ordered pore arrangement by employing two anodizing modes - galvanostatic mode and combined (galvanostatic + potentiostatic) mode, at high values of the current density and voltage. Use has been made of an oxalate electrolyte and a complex electrolyte comprising oxalic acid and phosphoric acid. Scanning electron microscopy has been used to investigate the surface morphology of the barrier and porous layers and to determine pore sizes and inter-pore distance.

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Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.

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