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Articles Related to MCC

Twenty Five Years of Drug Discovery at the University of California Targeting Kinetoplastid Parasites

This review summarizes 25 years of screening compounds against three major kinetoplastid parasites, Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp. The work was carried out at two University of California campuses by a consortium of scientists. The history of this effort is summarized beginning with DARPA and NIAID TDRU projects. The compound collections that were screened came from both academic and industry sources.
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Metastatic Leiomyosarcoma of the Inferior Vena Cava Presenting with a Hepatic Mass

A case report of a 72-year-old female patient presenting with right-sided abdominal pain and back pain, on which initial abdominal ultrasound revealed a hepatic mass.
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Wet Granulation to Overcome Liquisolid Technique Issues of Poor Flowability and Compactibility: A Study to Enhance Glibenclamide Dissolution

The aim of this study is to apply wet granulation on liquisolid powders to overcome issues of poor powder flowability and compressibility especially with using high viscosity liquid vehicles. Different liquisolid formulations were made using three excipients where the effect of each excipient used in the dissolution of the model hydrophobic drug (Glibenclamide) was evaluated. The Glibenclamide tablets were formulated using PEG 400, Synperonic PE/L44 and Cremophor ELP, at a 10 %w/w in liquid vehicle drug concentration. The carrier (Avicel®PH102) was used followed by colloidal silicon dioxide (coating material) that converted the wet mixture into dry powder. Potato starch, 5%w/w, as a disintegrant was mixed with the mixture manually for 10 minutes and was finalized by adding 0.75% of magnesium stearate as a lubricant.
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Recent Developments in Human Odor Detection Technologies

Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.
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Editorial Board Members Related to MCC

JOEL E. RICHTER

Professor
Department of Medicine
University of South Florida
United States

Irmo Marini

Department of Rehabilitation
University of Texas-Pan American
US

Mohsen Meydani

Professor
Friedman School of Nutrition Science and Policy
Tufts University
United States

ASISH K. SAHA

Associate Professor
Department of Medicine
Boston University
United States
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