Articles Related to MPA

The present study evaluated the efficacy and safety of biosimilar infliximab in patients with active rheumatoid arthritis on a stable dose of methotrexate. Subjects were assigned randomly to either study infliximab or reference infliximab product in an approved dose of 3 mg/kg as an intravenous infusion at week 0, followed by similar doses at Weeks 2, 6 and 14. Primary efficacy endpoint was the proportion of subjects achieving ACR20 criteria at week 16 and secondary efficacy assessment included proportion of subjects achieving ACR20, ACR50 and ACR70 at week 16. In the open-label phase, all responders were followed till week 54. The non-responders entered a follow-up phase for immunogenicity and safety for an additional 3 months.

View complete article: PDF  |  Full-text

This study tested for the effects of generic liposome-encapsulated doxorubicin hydrochloride (generic doxorubicin) compared to reference-pegylated liposomal doxorubicin hydrochloride (reference doxorubicin) as a treatment for patients afflicted with epithelial ovarian carcinoma whose disease has progressed after platinum-based chemotherapy. Chart-reviews of actual patients enrolled in a community-based NIH trial suggest that both generic and reference liposomal doxorubicin hydrochloride (HCl) are equally effective as treatment for ovarian cancer carcinoma.

View complete article: PDF  |  Full-text

Despite several studies having highlighted that candidaemia and invasive fungal disease (IFD) are associated with high mortality and increased costs, there are currently few published studies which provide an insight into real-life practice of invasive candidal diseases. In a medium-sized district general hospital in the UK we sought to compare the efficacy, safety and treatment cost of micafungin versus caspofungin and low dose of liposomal amphotericin B (L-AmB) 1mg/kg/day for the treatment of confirmed candidaemia or clinically diagnosed invasive fungal disease (CDIFD). In the present retrospective audit, a total of 126 patients with candidaemia or CDIFD were reviewed from hospital records and 94 were included in our audit.

View complete article: PDF  |  Full-text

To evaluate the value and safety of labetalol in comparison to Alfa methyldopa in treatment of pregnant women with pregnancy-induced hypertension (PIH). 264 patients with PIH were randomly distributed to take either methyldopa (group 1) labetalol (group 2). or Intake of medications with respect to Age, gravidity, Blood Pressure measurement, albumin in urine measurement Levels, Side Effects, dose of the drug, increasing duration of pregnancy, mode of delivery, Perinatal safety and APGAR scores were studied. The statistical level of significance was taken at P<0.05.

View complete article: PDF  |  Full-text

In the current study, we have experimentally and comparatively investigated and compared malignant human cancer cells and tissues before and after irradiating of synchrotron radiation using Two-Dimensional Infrared Correlation Spectroscopy, Linear Two-Dimensional Infrared Spectroscopy and Non-Linear Two-Dimensional Infrared Spectroscopy.

View complete article: PDF  |  Full-text

Objective: Concomitant chemoradiation (RCT) represents the standard of care for locally-advanced nasopharyngeal carcinoma (NPC).Nevertheless induction chemotherapy (IC) followed by RCT is currently an attractive approach. Some trials showed a survival benefit of this therapeutic strategy. The aim of this study was to analyze complete clinical response (CCR) after IC and to assess its impact on disease control and survival.

View complete article: PDF  |  Full-text

Background and Objective: In response to low consumption levels of fruits and vegetables (F&V) by Supplemental Nutrition Assistance Program (SNAP) participants, the Community Food Bank of Southern Arizona created the Double Up SNAP (DUSP) farmers’ market (FM) incentive program to examine its impact on awareness of and access to FM, and F&V purchase and consumption in Pima County, AZ.

View complete article: PDF  |  Full-text

A human being is having physical and biological body structure, even though each and every individual is having his own blood group, hair color, retina color, skin complexes, height, breadth etc. that result in his own bodily structure that differentiates with the other individual. After the certain age of subject nearly about twenty years, height or length of his organs or limbs are not increases and fixed bodily structure is built up.

View complete article: PDF  |  Full-text

Describes a case of a patient that presents with hippocampal atrophy leading to hyperkinetic crises of parietal-occipital origin

View complete article: PDF  |  Full-text

The Vespa orientalis venom, a secretary substance from arthropod wasps has attracted considerable interest as a potential source of pharmacological substances. Photo detoxified snake venom has been used for dementia, dengue fever, atherosclerosis, cancer, and diabetes. There was no scientific evidence on the photooxidized Vespa orientalis venom of Indian origin as well as its protein characteristic.

View complete article: PDF  |  Full-text

This study has a focus on patterns of work-related interactions, experiences, and attitudes expressed by leaders in the Swedish Police force.A cross-sectional design was used to compare police leaders (n=106) with reference groups recruited for public and private enterprises (n=1650). Work-related ratings were provided by use of a recruitment inventory JobMatch Talent (JMT). In this study, three main JMT scales (including subscales) concerned with relationships were used: Tolerance (h1: Assent image, h2: Tolerant attitude, h3: Trust in others); Social Interest (i1: Showing consideration, i2: Diplomacy, i3: Contact creating); Communication (j1: Impact, j2: Communicative, j3: Openness).

View complete article: PDF  |  Full-text

This study has a focus on patterns of work-related interactions, experiences, and attitudes expressed by leaders in the Swedish Police force.A cross-sectional design was used to compare police leaders (n=106) with reference groups recruited for public and private enterprises (n=1650). Work-related ratings were provided by use of a recruitment inventory JobMatch Talent (JMT).

View complete article: PDF  |  Full-text

Jing.Zou@staff.uta.fi

View complete article: PDF  |  Full-text

Ten recently extracted primary molars, were used in this study for the measurement of the shear bond strength. Occlusal enamel was ground, leaving a flat dentin surface, on which a cylindrical specimen of each of the two tested materials was applied and light-cured according to the manufacturer’s instructions. Specimens were then mounted in self-cure acrylic resin. Ten specimens were used for the measurement of the compressive strength. The specimens were prepared in a special-cylindrical mold, then light-cured according to the manufacturer’s instructions. The compressive and shear bond strength of each specimen was measured using a Universal Testing Machine.Ten specimens of each of the two resin materials were used to measure the abrasion resistance. The test was performed by means of a toothbrushing machine and abrasive dentifrice slurry. The specimens were weighed before and after the test. Weight loss of the specimens were calculated after the test and reported as percent weight loss. Regarding microleakage test, Class V cavities were prepared in the buccal surface of 36 exfoliated or extracted human primary molars.

View complete article: PDF  |  Full-text

Objective: To evaluate the compliance of chemotherapy administration duration by comparing the peripheral venous catheter (PVC) route with the implantable venous access device (IVAD).Keywords: Chemotherapy; Gravity perfusion; Peripheral venous; Implantable venous access deviceIntroduction Methods: This was a retrospective study that analyzed 566 cycles of chemotherapy administered by PVC at the Cancer Unit of Yalgado Ouédraogo University Hospital and 258 cycles administered by IVAD at the Oncology Department of Treichville University Hospital in Abidjan. We compared the differences between the programmed duration of chemotherapy and the actual duration of administration according to the two routes of administration.

View complete article: PDF  |  Full-text