Articles Related to National Institutes of Health

Cardiac myxomas are a potential source of emboli to the brain and elsewhere in the vascular tree. Myxomas are the most common benign primary cardiac tumor in adults. The commonest location of cardiac myxomas is in the left atrium followed by the right atrium and the remainder develops in the ventricles and rarely in the heart valves.

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Streptococcus pneumoniae is a leading cause of meningitis. Although rates of bacterial meningitis have decreased after pneumococcal conjugate vaccine introduction, pneumococcal meningitis has not been eliminated. In this case series, we describe the presentation, serotypes, and outcomes of 11 children with pneumococcal meningitis at a tertiary children’s hospital after the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced, from 2011-2013. The median age of children with meningitis was 7 years. The majority of the isolates (82%) were susceptible to penicillin. Most isolates (73%) were serotyped and there was no evidence of disease caused by serotypes contained in PCV7

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