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Articles Related to Neuroprogenitor induction

Human Induced Pluripotent Stem Cells Derived from A Patient with Sporadic Alzheimer’s Disease Exhibit Altered Neuronal Proliferative Capacity

We generated two hiPSC clones from a patient with sporadic late-onset Alzheimer’s disease (AD-iPSCs), which expressed typical undifferentiated markers and passed standard pluripotency assays. Genome-wide microarray analysis revealed that AD-iPSCs were highly similar to control hiPSCs and hESCs, albeit with some noticeable differences in few genes, viz.: DNAJC15, GRPR, NAIP and SNORD116-18
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