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Articles Related to OCT

Optical Coherence Tomography Angiography for Choroidal Neovascularization and Subretinal Fibrosis in Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is characterized by a progressive fragmentation and calcification of elastic fibers in connective tissue and when Bruch membrane (BM) is affected ocular modifications can be found. Recently, Optical coherence tomography-angiography (OCT-A) contribute to a better comprehension of lesions in PXE.
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Karoshi: A Sword of Damocles Hanging over Chinese High-pressure Doctors

A growing body of evidence gathered over the past 10 years has demonstrated a clear escalation of sudden death (SD) in Chinese medical staff. This retrospective study was conceived to explore the first evidence of signs of SD, relieving clinical workload and strengthening protection against the overload of Chinese medical staff.
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Is the Emergency Bag of the Doctor of a Rural Medical Capacity Ready for Emergencies? A Quality Improvement Project (QIP) in a Greek Rural Health Center

This article describes the procedure we followed in a small rural medical capacity in Greece, to improve a crucial aspect of the everyday clinical practice and adopt a culture of auto-regulation through the procedure of Audit. As Doctors of the Amfiklia Health Center we are often called to leave the office and deal with emergency cases out of the Health Center. It was common ground that the maintenance of the Emergency Bag we use in these cases is neglected. We audited our practice using certain standards, analyzed the findings, recommended regulations, implemented the changes and re-audited our practice. At the end of this project we managed to ensure that the Emergency Bag has almost all of the necessary drugs and consumables which will be in-date. We also managed to improve our practice with regards to the appropriate recording of the Controlled Drugs used during such cases.
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Physician and Patient Perspective to Weight Gain in Pregnancy

Gaining weight outside of the Institute of Medicine guidelines puts a woman and her foetus at an increased risk. Limited or incorrect information is being provided to women during antenatal care. Research shows that physicians do not perceive this as an important issue. We aimed to assess both physician and patient perspective to weight gain in pregnancy as well as assessing physicians current practice to weight management. 71% of women want to be given a target weight to gain during pregnancy; 87% want to be told if they are gaining an inappropriate amount of weight. 87.5% of physicians believe that weight management is important; 31.2% advise patients about weight gain.
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Bubonic Plague Outbreak Investigation in the Endemic District of Tsiroanomandidy - Madagascar, October 2014

Plague remains a major public health problem in Madagascar. Faced with reports of plague cases and deaths in Tsiroanomandidy district, we performed an investigation in October 2014.Our aim was to describe the plague outbreak and to improve the national plague control strategies. We used the National plague control program case definition. We identified cases from outpatient registers and collected socio-demographic and clinical information. Plague circulation was determined through a retrospective environmental survey of rodents and vectors.
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Derivation of Induced Pluripotent Stem (iPS)-like Cells from Microminipig Somatic Cells by Sendai Viral Transduction of 4 HumanG, OCT4, SOX2, KLF4, and c-MYC

Research on the stem cell biology of the minipig is rapidly developing. Although research on mouse and human stem cells currently predominates over that in other species, data from these species have provided a good foundation for current and future porcine stem cell research. In addition, the increasing popularity of alternate-species models in the study of human diseases and disease mechanisms has spurred porcine stem cell research. As a source of pluripotent embryonic stem cells, the pig presents several challenges as compared with mice and humans.
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Radiation Awareness amongst Junior Doctors

Recent literature has suggested that junior doctors’ knowledge of ionising radiation is inadequate. Advances in technology and availability have led to of these investigations being readily requested. Exposure is associated with adverse risks especially malignancy; therefore in accordance with the Ionising Radiation (Medical Exposures) Regulation (IR(ME)R), clinicians should be aware of radiation doses and their legal responsibility as referrers.
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Hirschsprung’s Disease in Adult Treated by Coloprotectomy and Colo-Anal Anastomosis

Hirschsprung’s disease is a rare pathology Most cases become manifest during the neonatal period, but in rare instances, the disease is initially diagnosed in adult patients.
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Spontaneous Coronary Artery Dissection: Efficient Clinical Outcome through Percutaneous Coronary Intervention

Spontaneous coronary artery dissection (SCAD) is a rare myocardial ischemic disease that threatens patients’ life. Various risk factors are associated with SCAD, such as smoking, severe hypertension and psychological reasons. Considering the formation of dissection, SCAD can be divided into intimal tear type or intraluminal hemorrhage type.
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Chromosomal Aberrations and HMGA2 Expression in Paroxysmal Nocturnal Hemoglobinuria

Somatic, inactivating PIGA mutations in haematopoietic stem cells, followed by an unknown autoimmune selection process in favor of the mutated clone, are thought to be important events in the pathogenesis of paroxysmal nocturnal hemoglobinuria (PNH). Recently, a second clonal event involving the HMGA2 gene was reported in some PNH cases, and over expression of this gene was postulated to promote proliferation of the mutated clone.
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Postoperative Chylothorax: Is Octreotide A Valid Therapy?

Chylothorax is an extremely rare and serious complication of cardiac surgery, with a poor outcome unless treated at the right time and in the right way. We report a case of a 76-year-old female who developed chylothorax after coronary artery bypass grafting.
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Unusual Large Ethmoidal Osteoma with Orbital Extension

Large osteomas of the fronto-ethmoidal cavities are very rare benign tumors. Headache and ocular signs are the most common symptoms. Imaging allows the diagnosis. Treatment of ethmoid sinus osteoma is surgical. One case with orbital extension is reported and discussed. A 30 years-old male; complaining of swelling of themedial angle of the right eye. Computed tomography showed a right ethmoidal process with orbital extension. The tumor was removed through an external ethmoidectomy.
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Review on Transdermal Drug Delivery Systems

Recently, transdermal drug delivery system (TDDS) has become a more and more important approach to administering drugs. Based on its advantages, which are not achievable by other modes of administration, many researchers are dedicated to the study of it, and have made great progress. Although the skin offers a painless interface for systemic drug delivery, it also presents limitations which are mainly caused by the stratum corneum.
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The Association of Grades of Photoreceptor Inner Segment-Ellipsoid Band Disruption with Severity of Retinopathy in Type 2 Diabetes Mellitus

A prospective case-control study was undertaken to evaluate the association of inner segment-ellipsoid (ISel) band disruption with severity of diabetic retinopathy on spectral-domain optical coherence tomography. ISel disruption was graded as - grade 0: intact ISel; grade 1: focal disruption (subfoveal ISel disruption) and grade 2: global disruption (ISel disruption involving macular cube). Increased severity of diabetic retinopathy was found to be associated with increase in disruption of ISel (r = 0.49, p < 0.001).
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Feasibility Analysis of Autogenous Tooth-based Bone Graft Material after Guided Bone Regeneration Technique

We set out to determine the possibility of radiographically evaluating the degree of marginal bone loss in humans after functional loading of implants at sites of guided bone regeneration (GBR) with autogenous tooth-based bone graft (ATBBG) material (AutoBT®, Korea Tooth Bank, Seoul, Korea).
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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Editorial Board Members Related to OCT

Chandra M Valmikinathan

Department of Biomedical Engineering
Georgia Institute of Technology
United States

Lufang Zhou

Lufang Zhou
Assistant Professor
The University of Alabama
Birmingham
United Kingdom

Aly Soliman Hamed Derbalah

Professor
Pesticides Chemistry and Toxicology Department
Faculty of Agriculture
Kafr-El-Shiekh University
Egypt

Ranjana Bhattacharjee

Molecular Geneticist
Bioscience Center
IITA, Ibadan
Nigeria

Alex Bekker

Professor and Chair, Department of Anesthesiology
Professor, Department of Physiology and Pharmacology
Rutgers New Jersey Medical School
United States

Nicole Lovato

Adelaide Institute for Sleep Health: A Flinders Centre of Research Excellence
College of Medicine and Public Health
Flinders Universitybr/> Australia

Yue Chen

Assistant Professor
Department of Biochemistry, Molecular Biology and Biophysics,
University of Minnesota
United States

Doug Fairlie

Division of Structural Biology
The Walter and Eliza Hall Institute of Medical Research
Australia

Zhuoxiao Cao

Scientist
Cell biology department
Novo Nordisk China R&D
China

JONATHAN K. MURASKAS

Professor
Department of Pediatrics and Obstetrics/Gynecology
Loyola University Medical Center
Loyola University Stritch School of Medicine
United States
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