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Articles Related to Obesity

Factors Associated with Junk Food Consumption Affecting Saudi University Female Students

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Rare Heterozygous PCSK1 Variants in Human Obesity: The Contribution of the P. Y181H Variant and a Literature Review

Deficiency of proprotein convertase 1/3 (PC1/3), is a known cause of monogenic obesity. This protein is encoded by the proprotein convertase subtilisin/kexin type 1 (PCSK1) gene and PC1/3 deficiency patients carry either homozygous or compound heterozygous PCSK1 variants. Previously, it was also reported that heterozygous PCSK1 variants, causing partial PC1/3 deficiency, resulted in a significant increased risk for obesity. This effect was almost exclusively generated by the rare p.Y181H (rs145592525, GRCh38.p13 NM_000439.5: c.541T>C) variant, which was shown to affect proper PC1/3 maturation but not its enzymatic capacity. As most of the identified individuals with the heterozygous p.Y181H variant were of Belgian origin, we performed a follow-up study in a population of 481 children and adolescents with obesity, and 486 healthy and lean individuals, recruited from Belgian hospitals. We identified three obese (0.62%) and four lean (0.82%) p.Y181H carriers (p = 0.506), indicating no association of the variant with obesity. Next, haplotype analysis was performed in 13 p.Y181H carriers, 20 non-carriers (10 with obesity and 10 lean) and two p.Y181H families. All heterozygous carriers were found to share the same haplotype (p < 0.001). Together with the higher frequency of this variant in Central European populations and the notably high frequency in the Belgian population, this indicates a possible founder effect for the p.Y181H variant. State-of-the-art literature concerning the role of rare heterozygous PCSK1 variants similarly implies them to be rarely associated to monogenic obesity, as first-degree carrier relatives of patients with PC1/3 deficiency are mostly not reported to be obese. Furthermore, recent meta-analyses have only indicated a robust association for scarce disruptive heterozygous PCSK1 variants with obesity, while clinical significance is less or sometimes lacking for most nonsynonymous PCSK1 variants.
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A Web-Based Nutrition Education Study in Alabama Black-Belt Counties During the Covid-19 Pandemic

Overweight and obesity continue to be health-related issues in Alabama Black-Belt Counties with rates ranging from 35 to 48%. We aimed to determine the impact of a web-based nutrition education and physical activity intervention on participants’ health in Alabama Black Belt counties during the COVID-19 pandemic. Nutrition education was delivered to participants through a zoom online platform for 12 weeks. Participants’ knowledge, attitudes, and practices as well as changes in nutrition knowledge, anthropometry, and blood pressure were determined through online surveys. Of the participants, (100%) indicated that overweight and obesity are a result of unhealthy lifestyles, whereas 90.7% reported that obesity increased the risk of high blood pressure (90.7%), diabetes (86.04%), and heart disease (90.7%). Results showed that participants’ income was a significant determinant of their perception for the role of schools in fighting obesity (χ2=0.04). Similarly, data revealed that the age of participants was a significant factor for: their desire to learn more about obesity (χ2=0.04), perception of their knowledge of overweight and obesity compared to the average person (χ2=0.01), and the perception that they had an excellent knowledge of overweight and obesity (χ2=0.05). There were significant improvements in knowledge scores. Results showed a significant decline in waist circumference (p<0.001) and hip circumference (p<0.02); 60% of the participants showed a decline in bodyweight; 43% lost more than 1-5kg, while 9.8% maintained their baseline weight. Web-based virtual interactions may effectively substitute or complement face-face nutrition education and lead to a reduction of overweight and obesity in Alabama Black-Belt counties.
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Italian Survey on Perception of Obesity and Bariatric and Metabolic Surgery: A Comparison between General Practitioners and Obese Patients

Obesity is a pandemic, chronic and relapsing disease with several treatment options. The aim of this work was to investigate the level of awareness that people with obesity (PwO) have of their own condition and the level of knowledge regarding possible treatments available. To compare and contrast collected data on PwO with data obtained from general practitioners (GPs)
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Factors Influencing Overweight and Obesity in Nurses: A Systematic Review and Meta-Analysis

WHO reports a high global prevalence of overweight and, which is prevalent among nurses and results in poorer health, work productivity and patient care. Existing studies have established the relationships between multiple demographic and work-related factors and overweight and obesity, but no review investigated which factors are associated with overweight and obesity in nurses.
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Comparison of Anthropometric Indicators of Overweight and Obesity in Children and Adolescents

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Capsaicinoids Increase Resting Metabolic Rate in Healthy Individuals under Fasting Condition

Obesity is a chronic metabolic condition of energy imbalance where energy intake exceeds energy expenditure. Resting energy expenditure (REE) represents calories burned at rest and accounts for >60% of total energy expenditure and is an important target for management of obesity. Capsaicinoids, extracted from Capsicum annuum have previously been shown to increase metabolism, lipolysis & induce satiety.
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Anthropometric Measures of Obesity to Predict Mortality using Edmonton’s Obesity Staging System, among Young Sudanese Females at Khartoum Locality, Sudan

Obesity is considered a serious health hazard. It predisposes the individual to many disorders, such as diabetes and heart disease, it shortens the life span, and it complicates childbirth and surgery. This study was a cross-sectional study conducted in health centers at Khartoum locality during November 2018- January 2019; aimed to predict mortality among a young female Sudanese population enrolled in health centers.
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Prevalence and Factors Associated with Overweight and Obesity among Adults in the Selected Towns of Western Ethiopia: A Community Based Cross-Sectional Study

The risk of overweight and/ or obesity is one of the increasing conditions worldwide touching both the developed and developing countries. It is becoming much devastating specially in town population. The aim of this study was to assess the prevalence of overweight/obesity and the associated risk factors among adults residing in the selected towns of western part of Ethiopia.
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Comparative Effect of a High Fat with or without High Levels of Sucrose Diets on Peripheral Neuropathy in C57BL/6J Mice

Feeding mice a diet containing high fat and high sucrose has been promoted as a good model for type 2 diabetes. This study sought to determine the effect of feeding mice a high fat and high sucrose diet on neuropathy compared to mice fed only a high fat diet and mice fed a high diet and treated with streptozotocin.
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Fractional Exhaled Nitric Oxide (FeNO) in Healthy Obese Adults

It was a cross-sectional study including 434 apparently healthy subjects (194 males) divided into two groups: i) obese (BMI ≥ 30 Kg/m²) and ii) non-obese (BMI < 30 Kg/m²). Exclusion criteria were: current smokers, asthma, medicine intake interfering with FeNO levels, and abnormal lung function tests. The FeNO measurements were performed before spirometry. Student t test was performed to compare between the two groups. The Spearman correlation between BMI and FeNO levels was evaluated. The Piecewise linear regression with breakpoint was assessed to define the breakpoint of inflammation related to obesity.
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Does Obesity Increase the Risk of Brain Damage following COVID-19 Infection?

Neurological impairments associated with Covid-19 have been the subject of numerous investigations since the end of 2019, when the SARS-CoV-2 virus appeared and showed a staggering rise worldwide. Neuroimaging in patients infected with Covid-19 revealed the apparition of severe brain pathologies, such as acute perfusion deficits and white matter abnormalities, meningeal enhancement, basal ganglia lesions, intracranial hemorrhage, encephalitis, cerebral venous thrombosis, encephalopathy, and stroke [1,2].
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How Nurse Education Impacts Her Career?

A great proportion of healthcare services need high-quality medication and nursery. For high-quality nursery needs best nurses and their education. Gradually, different types of nursery education systems can impact their life and career. In the future, more parameters can be used for judging the quality and promotion of nurses. This editorial addresses different educational efforts for their progresses in medical knowledge promotion, technical capability improvement and salary promotion.
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Ketogenic Diet Versus a Standard Low-Calorie Diet to Treat Mildly Obese Patients in an Outpatient Clinic: An Observational Retrospective Study

The aim of this study is to evaluate the effectiveness of a Very Low-Calorie Ketogenic Diet (VLCKD) compared to a LowCalorie Diet (LCD) in the treatment of mildly obese patients. We aimed to highlight the difference in weight loss, compliance, physical activity levels and drop-out rates between the VLCKD group and the standard LCD one.
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Exhaled Volatile Organic Compounds and Vagal Tone are Different in Patients with Overweight or with Obesity: Practical Consequencies

Urinary Volatile Organic Compounds have been associated with type 2 diabetes mellitus and overweight and may correlate with Exhaled Volatile Organic Compounds (E-VOCs).
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Editorial Board Members Related to Obesity

DONALD K. INGRAM

Adjunct Professor
Pennington Biomedical Research Center
Louisiana State University
United States

Mohamed Eddouoks

Professor
Faculty of Sciences and Techniques Errachidia
Moulay Ismail University
Morocco

Liqing Yu

Associate Professor
Departments of Animal and Avian Sciences
University of Maryland
United States

Magdalena Pilska

Assistant Professor
Faculty of Human Nutrition and Consumer Sciences
Warsaw University of Life Sciences
Poland

Andreu Palou

Professor
Laboratory of Molecular Biology, Nutrition and Biotechnology
University of the Balearic Islands
Spain

KEQUAN ZHOU

Associate Professor
Department of Nutrition & Food Science
Wayne State University
United States

Edralin A Lucas

Associate Professor
Department of Nutritional Sciences
Oklahoma State University
United States

VICTORIA J VIEIRA-POTTER

Assistant Professor
Department of Nutrition and Exercise Physiology
University of Missouri
United States

Jyotsna Sharman

Assistant Professor
Department of Health and Human Performance
Radford University
United States

YUNBO LI

Professor
Department of Pharmacology
Campbell University School of Osteopathic Medicine
United States
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