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Articles Related to Overweight

Rare Heterozygous PCSK1 Variants in Human Obesity: The Contribution of the P. Y181H Variant and a Literature Review

Deficiency of proprotein convertase 1/3 (PC1/3), is a known cause of monogenic obesity. This protein is encoded by the proprotein convertase subtilisin/kexin type 1 (PCSK1) gene and PC1/3 deficiency patients carry either homozygous or compound heterozygous PCSK1 variants. Previously, it was also reported that heterozygous PCSK1 variants, causing partial PC1/3 deficiency, resulted in a significant increased risk for obesity. This effect was almost exclusively generated by the rare p.Y181H (rs145592525, GRCh38.p13 NM_000439.5: c.541T>C) variant, which was shown to affect proper PC1/3 maturation but not its enzymatic capacity. As most of the identified individuals with the heterozygous p.Y181H variant were of Belgian origin, we performed a follow-up study in a population of 481 children and adolescents with obesity, and 486 healthy and lean individuals, recruited from Belgian hospitals. We identified three obese (0.62%) and four lean (0.82%) p.Y181H carriers (p = 0.506), indicating no association of the variant with obesity. Next, haplotype analysis was performed in 13 p.Y181H carriers, 20 non-carriers (10 with obesity and 10 lean) and two p.Y181H families. All heterozygous carriers were found to share the same haplotype (p < 0.001). Together with the higher frequency of this variant in Central European populations and the notably high frequency in the Belgian population, this indicates a possible founder effect for the p.Y181H variant. State-of-the-art literature concerning the role of rare heterozygous PCSK1 variants similarly implies them to be rarely associated to monogenic obesity, as first-degree carrier relatives of patients with PC1/3 deficiency are mostly not reported to be obese. Furthermore, recent meta-analyses have only indicated a robust association for scarce disruptive heterozygous PCSK1 variants with obesity, while clinical significance is less or sometimes lacking for most nonsynonymous PCSK1 variants.
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Factors Influencing Overweight and Obesity in Nurses: A Systematic Review and Meta-Analysis

WHO reports a high global prevalence of overweight and, which is prevalent among nurses and results in poorer health, work productivity and patient care. Existing studies have established the relationships between multiple demographic and work-related factors and overweight and obesity, but no review investigated which factors are associated with overweight and obesity in nurses.
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Comparison of Anthropometric Indicators of Overweight and Obesity in Children and Adolescents

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Prevalence and Factors Associated with Overweight and Obesity among Adults in the Selected Towns of Western Ethiopia: A Community Based Cross-Sectional Study

The risk of overweight and/ or obesity is one of the increasing conditions worldwide touching both the developed and developing countries. It is becoming much devastating specially in town population. The aim of this study was to assess the prevalence of overweight/obesity and the associated risk factors among adults residing in the selected towns of western part of Ethiopia.
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Exhaled Volatile Organic Compounds and Vagal Tone are Different in Patients with Overweight or with Obesity: Practical Consequencies

Urinary Volatile Organic Compounds have been associated with type 2 diabetes mellitus and overweight and may correlate with Exhaled Volatile Organic Compounds (E-VOCs).
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Overweight and Obesity and their Relationship with Glucose Dysregulation in the Nigerian Youth

Fasting plasma glucose is a risk factor for diabetes and cardiovascular disease in obese children. This study aimed to evaluate the association between WC, BMI and WHtR and blood glucose in children.
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Effects of Ramadan Fasting on Anthropometric Measures, Blood Pressure and Glucose Level among Type 2 Diabetic Patients on Metformin Treatment

Fasting from dawn to dusk during Ramadan is obligatory for all healthy adult Muslims.
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Metabolic Effects of an Inositol-Resveratrol Nutraceutical Combination in Non-Diabetic Overweight/Obese Subjects with Altered Glucose Tolerance

Insulin resistance (IR) is almost constistently associated with overweight or obesity in both diabetic and non-diabetic subjects. Nutraceutical compounds improving insulin resistance (IR) may be useful in prevention and treatment of cardiovascular (CV) risk factors in metabolic diseases.
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Overweight and Obesity in Women: Factor Analysis of Data from the Kenya Demographic and Health Survey

Overweight and obesity are emerging public health challenges in low-to-middle-income countries. Factors such as urbanization, physical inactivity, changing diets, and harmful consumption of alcohol contribute to this global growth in overweight and obesity, particularly in African countries. This study aimed to identify factors most predictive of overweight and obesity in adult women in Kenya.
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Impact of Eating Habits on Cellular Regeneration and Weight Balance in the Central African Republic

Food compound has an impact on cell regeneration and body mass index. Studies of observations conducted between 2015 and 2017 among men in the CAR show a similarity in eating habits and in the way of consuming food. Of 148 people from different households with different incomes observed, 79 or 53.38% were male and 69 or 46.32% were female. The median age was 28 years (18-45). In group 1 or G1, 115 (77.7%) retained the African food habit. In addition, 33 people or 22.3% adopted a western-style eating habit and have a preference for fried foods and dairy products with a high-fat content (group 2 or G2). This G2 had more overweight or obesity phenomena than the G1 which presented some weight loss cases with a significant difference. The composition of the African food habit has certainly an influence on the body mass and cellular regeneration thus tissue.
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Measure: Multiprofessional Intervention in Overweight and Obesity of Users Assisted in the Primary Health Care

Obesity is a contemporary phenomenon that consumes an enormous and substantial public expense regarding health for needy countries. The amount spent only for the cost with the treatment of obesity for the SUS (The Unified Health System) was estimated around half a billion of reais in 2011 (Oliveira, 2013) [1]. In this scenery, the purpose towards prevention and control initiatives concerning these outlines must really become fundamental. This study has aimed to analyze the efficacy developed by a multidisciplinary team during a period of 12 months (from 2016 to 2017). The intervention has consisted in a number of periodic consultations supervised by this special team within food directions and physical training. All the data were synthesized and analyzed statistically through the Mcneunann Test, regarding the significance degree of p< 0.05. It has been observed in such results that most of the participants belong to feminine sex having from 45 to 81 years of age, a low schooling and a short monthly income. For the present, what must be said is that the intervention was wholly effective providing reduction of corporal measures, improvement in the quality of the diet consumed, besides a strengthening in the social network, empowering for the participants, further the expansion of knowledge about topics relative to food and nutrition. So, it can finally be suggested that initiatives towards obesity control are indeed effective and important and must be promoted everywhere.
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Association between Physical Activity and Body Weight: Health Creation and Disease Prevention

Leisure time physical activity has a broad spectrum of health benefits. The objective of this study was to provide evidence and to support the association between physical activity and body weight. We used data from a probability sample of 8,128 individuals residing in Montreal (Canada). Multinomial multivariate logistic regression was used to determine the association between physical activity and body weight. Results showed no statistical association between physical activity and underweight. However, physical activity was associated with overweight, namely individuals doing less physical activity were significantly more likely to be overweight (OR=1.42; 95%CI=1.18- 1.69) than those performing intense physical activity. Additionally, the association between physical activity and obesity showed a negative incremental relationship, i.e. individuals reporting moderate physical activity were 29% more likely to be obese (OR=1.29; 95%CI=1.07- 1.55), and those reporting low physical activity were 123% more likely to be obese (OR=2.23; 95%CI=1.80-2.76) compared to intense physical activity status. Leisure time physical activity and overweight/obesity were significantly associated after accounting for several socioeconomic, lifestyle and health-related correlates. Due to the broader positive impact of physical activity on the health status of the individual, we advise health authorities to facilitate the propagation of healthy lifestyle in the community by adopting a health-creation policy in addition to the conventional disease-prevention strategy
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Overweight and Obesity among Adults Aged 18-45 Years Residing in and around Giyani Town in Mopani District of Limpopo Province, South Africa

Objective: To describe the prevalence of overweight and obesity among adults aged 18-45 years residing in and around Giyani town. Methods: This study included 100 participants recruited from a location in Greater Giyani Municipality of Mopani district, Limpopo Province, South Africa. This Municipality was purposively selected and convenience sampling was used to choose study participants. Body weight and height were measured using standard techniques. Waist circumference, systolic, diastolic, glucose, cholesterol and body fat levels were also assessed.
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Effect of Cold Wet sheet Pack on Body Temperature among Healthy Individuals - Result of a Single Arm Study

Hydrotherapy, as the name suggests is the most ancient method of treating diseases by using water in its various forms. The use of water for therapy has been around for hundreds of years. The cold wet sheet pack is one of the common hydrotherapy techniques used for reducing body weight. There have been no documented studies conducted to scientifically evaluate this effect. This study is an attempt to examine the effect of cold wet sheet pack on body temperature. Application of cold wet sheet pack for particular duration increases the body temperature by utilization of calories thus may leads to reduction of bodyweight. Thirty healthy volunteers were randomly selected from medical students enrolled in a naturopathic programme. The participants were of both sexes aged between 18 and 25 years under normal Body mass index (18.5-25). A cold (20 oC± 1 oC) wet sheet pack has given to each of the participants for one hour duration. The outcome measures were resting blood pressure, body temperature and pulse rate. 30 Participants were successfully completed the study, all participants have shown a raise in body temperature after intervention which was statistically significant (P=0.003). There is no significant change in blood pressure and pulse rate. Also there was a week positive correlation between body mass index and body temperature. A cold wet sheet pack for one hour has shown a raise in body temperature, which indicate that the cold wet sheet pack have a role in reducing body weight by utilizing the calories. However, these observations are based on a short term single arm pre-post design on healthy students. A cold wet sheet pack has been demonstrated in this study to have a significant effect in increasing body temperature and shows perspiration by utilization of calories. Large scale randomized control trials in obese patients over a longer period are warranted to conform the results which was uncovered in this study.
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The Effectiveness of an Activity Meter for Overweight Children and Their Caregivers in a Clinical Setting: a Pilot Study

Childhood obesity is epidemic in the United States, but low levels of physical activity and high levels of screen time are modifiable risk factors. An activity meter (AM) program, that utilizes an interactive child-focused website and measures the amount and intensity of physical activity, may promote activity and decrease BMI.The current study tests the feasibility of using an AM program with child-caregiver pairs in a primary care setting. We hypothesize that participants would rate the system as easy to use, would be motivated with their engagement in physical activity, and would continue to use and recommend to others. We hypothesize the AM system would increase children’s physical activity levels and decrease engagement in screen time over the study period. We also measure changes in participants’ body mass index (BMI).Prospective study assessing ease of use and satisfaction with the AM program post-intervention and comparing physical activity and BMI changes in children and caregivers from pre- and post-intervention over a 4-month period.
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Editorial Board Members Related to Overweight

Sununta Youngwanichsetha

Assistant Professor
Faculty of Nursing
Prince of Songkla University
Thailand

Kathy K Isoldi

Assistant Professor
Department of Nutrition
Long Island University
United States

Ana Cristina Lindsay

Associate Professor
Department of Nutrition
University of Massachusetts Boston
United States

Chandan Saha

Associate Professor
Department of Biostatistics
School of Medicine
Indiana University
United states
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