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Isolated Temporal Bone’s Paget Disease: A Case Report

Paget’s bone disease (PBD) is a benign tumor of osteoclasts. We report a case of an isolated temporal bone’s Paget disease with unusual evolution to a rapidly functional degradation of vestibulocochlear system. A 60 years old female was admitted for an isolated, left sided mastoid tumefaction without any inflammatory signs. Initial temporal bone computed tomography (CT) showed a left cotton wool appearance without any ossicles lesion or vestibulocochlear extension. Anatomo pathological tests confirmed the diagnosis. The outcome was marked by the occurrence of vestibulocochlear symptoms. Treatment had consisted on subtotal surgery in combination with oral bisphosphonate with improvement of her clinical conditions. The post operative’s follow-up was simple without any abnormalities. PBD of temporal bone is a benign disorder. Imaging is considered the most useful diagnosis modality for revealing the disorder that will be confirmed by histological tests. The treatment is based on medical approaches and surgery has few indications.
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Novel analytical technologies of Quality in the Sheep & Goat Dairy Sector

France, Greece, Italy, and Spain the major sheep and goat milk producers in Europe, got the initiative through an interim of 30 years (1985 – 2015), to organize - through IDF - 7 symposiums aiming at the upgrade of the Dairy Sector. One major interest was the milk quality. Stepwise, the efforts followed cow milk structural development in organizing the testing laboratory, the definition of quality in composition (fat, protein, lactose, total solids), in Hygienic (Total Bacteria Count, Somatic Cell Count, antibiotics residues and Aflatoxin M1 contamination), adulteration with water and detection of milk species. EU, by Decision 2002/657/EC, defined the rules for the Directive 96/23/EC, enumerated the testing methods, the demands in sampling procedures, the minimum limits of performance, the quality control (ISO 17025) and the interpretation of results. The equivalency of results from different laboratories, through ISO 17025, demanded the application of ISO analytical standards.
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Dental Implant Complications –Systemic Diseases- PART-I

Although dental implants have been a successful option for replacement of lost dentition for nearly five decades, their use in the medical and dental treatment plan is still in its youth. Literature on the medical implications of dental implants is surprisingly sparse, with a need for organization. This review is an attempt to begin the process of documenting the science behind this complex, yet critical topic.
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Pharmacokinetics, Biotransformation, Distribution and Excretion of Empagliflozin, a Sodium-Glucose Co-Transporter (SGLT 2) Inhibitor, in Mice, Rats, and Dogs

The metabolism, pharmacokinetics, excretion and distribution of a sodium-glucose co-transporter (SGLT 2) inhibitor, empagliflozin, were studied in mice, rats and beagle dogs following a single oral or intravenous administration of [14C]-empagliflozin. Empagliflozin was well absorbed in all species after oral administration.
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Identification of an Outer Membrane Protein from Actinobacillus Pleuropneumoniae Serotype 7

Actinobacillus pleuropneumoniae causes porcine pleuropneumonia, a disease which occurs world-wide and affects pigs of all ages. The study on the protective immune mechanism is not thoroughly clear. An outer membrane protein (OMP) was identified by screening a phage library of 3~8kb random DNA fragments of A. pleuropneumonia serotype 7.
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Editorial Board Members Related to PAGE

Alamgir Hossain

Professor
Department of Chemistry
Jackson State University
United States

PAUL G HORGAN

Professor
Department of Surgery
University of Glasgow
United Kingdom

Jagriti Narang Malhotra

Assistant Professor
Amity University
Noida
India

Efimia Papadopoulou-Alataki

Assistant professor
Aristotle University of Thessaloniki
Papageorgiou Hospital
Greece
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