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Articles Related to Pharmacology

Charles Bonnet Syndrome: Rapid Resolution of Visual Hallucinations with Low Dose Risperidone

Charles Bonnet syndrome (CBS) comprises of complex visual hallucinations secondary to visual impairment in the presence of preserved cognition. Age related macular degeneration and other factors causing visual deterioration lead to visual hallucinations in 10-15% of patients. Sensory deprivation and social isolation are risk factors for development of CBS. The distressing hallucinations are underreported by patients and to date there are no robust evidence based guidelines to manage these hallucinations. Since visual hallucinations are associated with multiple psychiatric disorders as well, these patients are often referred to mental health providers. Here, we present the case of CBS development after macular degeneration. Rapid and sustained resolution of visual hallucinations and associated distress was observed with low dose Risperidone.
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The Dose and its Acute Toxicology: A Systematic Review Article in the First Phase of Experimental Pharmacology

Hundreds and thousands of acute toxicity studies are conducted in experimental pharmacology with assumption hypothesis every year. It is usually concluded with inadequately validated data during the period of investigation within 24 hours.
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Veterinary Considerations for the Theoretical Resurrection of Extinct Species

The de-extinction of the dinosaur is a dubious possibility but its consideration brings forth some issues that are at least worthy of scientific discussion. In this review, we discuss two distinct issues that have implications for a de-extinct species such as a dinosaur: the ability, or lack thereof, to safely sedate a rare and potentially fractious animal capable of harming the veterinary staff tasked with its care; and, disease risks associated with a species that has been extinct for millions of years. To identify potential sedatives, comparative pharmacology will be needed to uncover the links between receptor pharmacology and the desired clinical outcomes of activating established alpha-2 adrenergic, opioid, and benzodiazepine receptors. Specific to disease control, it will be necessary to understand the unique susceptibility of the new species to current diseases as well as predicting their reservoir capacity for potential human and veterinary pandemic diseases. While the topics presented herein are not exhaustive, this review highlights some of the foremost research that should be conducted in order to serve the unique veterinary needs of a de-extinct species using the dinosaur as a paradigm. Addressing these issues should be considered if an intact dinosaur genome becomes available, regardless of the feasibility of dinosaur resurrection.
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Pharmacy Compounding Quality Control and Pharmaceutical Development Strategies for Seventeen alpha Hydroxyprogesterone Caproate in Prevention of Preterm Delivery

Seventeen alpha hydroxyprogesterone caproate (17-OHPC) is the only FDA-approved drug labeled for prevention of preterm delivery. This drug is also available as a compounded product from licensed compounding pharmacies. This article reviews the FDA approval history and pharmacy compounding quality control data of 17-OHPC, as well as briefly discusses possible future pharmaceutical development strategies for 17-OHPC.
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Treatments for Atopic Dermatitis

Atopic dermatitis, also known as eczema, affects about 10-20% of children in the UK and about 1-3% of adults [1]. The incidence of atopic dermatitis has increased as much as 3 fold in the past 40 years
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Editorial Board Members Related to Pharmacology

Burton M. Altura

Professor
Department of Medicine
Suny downstate medical center
United States

Norio Yasui-Furukori

Associate Professor
Department of Neuropsychiatry
Hirosaki University School of Medicine
Japan

Marco Weiergraber

Principal Investigator & Group leader
Neuropsychopharmacology
Federal Institute for Drugs and Medical Devices
Germany

P. S. SURESH

Assistant Professor
Department of Bio-Sciences
Mangalore University
India

Joseph Prandota

Emeritus Full Professor
Department of Pediatrics & Clinical Pharmacology
Faculty of Health Sciences
Wroclaw Medical University
Wroclaw
Poland

MASAYOSHI YAMAGUCHI

Professor
Department of Hematology and Medical Oncology
Emory School of Medicine
Emory University
United States

Zhiyuan Li

Professor
Laboratory of Ion Channels Research
Guangzhou Institute of Biomedicine and Health
Chinese Academy of Sciences
China

Masayoshi Yamaguchi

Adjunct Professor
Department of Hematology and Biomedical Oncology
Emory University School of Medicine
United States

Vincenzo Cuomo

Professor
Department of Physiology and Pharmacology
Sapienza University of Rome
Italy

CHARLES C. MUSCOPLAT

Professor
Department of Food Science and Nutrition
University of Minnesota
United States
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