Articles Related to Polyvinylpyrrolidone
Formation of Gold Nanoprisms on Atomically Flat Mica Surface
A numerous methods are being used for synthesis of gold nanoparticles (NPs) in liquid media, in micelles and at different interfaces. The size and geometry of NPs depend on parameters of synthesis. Here we propose the growth of Au NPs on atomically flat mica surfaces. In such conditions the monocrystalline and isotropic NPs are being simultaneously formed on the surface.
Wet Granulation to Overcome Liquisolid Technique Issues of Poor Flowability and Compactibility: A Study to Enhance Glibenclamide Dissolution
The aim of this study is to apply wet granulation on liquisolid powders to overcome issues of poor powder flowability and compressibility especially with using high viscosity liquid vehicles. Different liquisolid formulations were made using three excipients where the effect of each excipient used in the dissolution of the model hydrophobic drug (Glibenclamide) was evaluated. The Glibenclamide tablets were formulated using PEG 400, Synperonic PE/L44 and Cremophor ELP, at a 10 %w/w in liquid vehicle drug concentration. The carrier (Avicel®PH102) was used followed by colloidal silicon dioxide (coating material) that converted the wet mixture into dry powder. Potato starch, 5%w/w, as a disintegrant was mixed with the mixture manually for 10 minutes and was finalized by adding 0.75% of magnesium stearate as a lubricant.