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Hydroxyapatite Deposition Disease- Spontaneous Resolution of Significant Post Treatment Deposit

Calcific deposits are commonly seen on imaging done for other reasons. However, it can also present with periarthritis and adhesive capsulitis leading to severe disabling pain. Many theories have been proposed to explain the etiology and it is considered idiopathic by some. The management is also debatable, Barbotage being the most popular. In the majority of the cases it disappears spontaneously, requiring intervention like Barbotage and surgery only in a few cases. We present a case of a 45 year old female patient who had these calcific deposits in an unusual location of her right shoulder. These disappeared partially on conservative treatment. Subsequently, she developed severe pain in her right shoulder with restriction of all her movements. The pain was severe enough to interfere with her sleep. As a result she underwent barbotage. During the procedure an attempt was made to aspirate the calcific deposit in its entirety. This was not possible due to clogging of needle several times. There was complete resolution of pain following the procedure. However, post- procedure Magnetic resonance imaging (MRI) revealed a significant residual calcification which completely resolved 02 months after therapy with no recurrence.
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Gross and Histopathological Alterations in Experimental Trypanosoma Evansi Infection in Donkeys and the Effect of Isometamidium Chloride Treatment

Trypanosoma evansi (T. evansi) infection causes wasting and fatal animal trypanosomosis. This study was aimed at determining the gross and histopathological alterations in donkeys experimentally infected with T. evansi and the effect of isometamidium chloride treatment. Apparently healthy donkeys (N=18) of mixed sexes were randomly assigned to 3 groups; A1 (Infected-untreated), A2 (Infected, isometamidium-treated) and B (Uninfected, control) of six animals each. Each animal in infected groups had about 2.0x106 T. evansi injected through the jugular vein. Parasitaemia levels were evaluated using HCT and Mice Inoculation Test (support test). Gross and histopathological examinations were also conducted post-infection and post-treatment.
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