Articles Related to Protein

A trial was carried out on growing lambs to compare conventional protein supplementation of sugarcane with soybean meal with Saccharomyces cerevisiae enrichment produced by solid-state fermentation. Yeast enrichment enabled sugarcane stalks to increase their crude protein content from 4% to 12%. No difference was obtained between these two forms of supplementation on the daily growth of 80.2 and 76.8 g per day for enriched and non-enriched sugarcane respectively.

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Candida albicans is an opportunistic agent that can produce systemic infections in immunosuppressed patients. By varying its cell wall antigens this fungus can evade the immunological response by varying its cell wall antigens. On the other hand, Larrea divaricata Cav. (Jarilla) is a widely spread plant in America and it is used in folk medicine to treat several pathologies. It has been shown that antibodies against Jarilla proteins of crude extract (JPCE) cross-react with proteins of other microorganisms such as Gram-negative bacteria.

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Stress of the endoplasmic reticulum (ER) is induced by the accumulation of misfolded proteins in this organelle. It can be triggered by biotic and abiotic stress (particularly heat), but also by chemical treatments (such as DTT and tunicamycin) at a laboratory scale. To respond to this stress, various cellular mechanisms are involved, including the highly conserved protein repair pathway, the UPR (Unfolded Protein Response). This pathway aims to restore protein homeostasis in cells. In cereals, seed storage proteins (SSP) represent one of the characteristics that determine grain quality and are of great interest to agriculture. Unlike dicots, the dynamics of the UPR induction pathway in monocots are poorly documented in the literature.

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Using kinetic differential equations and the Runge-Kutt algorithm, an analysis of the pathological processes occurring in the course of Alzherimer’s disease was carried out. Thanks to the appropriately selected kinetic equations, the presented model allows to explain the time course of the growth of pathological proteins: beta-amyloid and tau protein and the related loss of nerve cells. The model is based on previous experimental knowledge of Alzherimer’s diseas and is in good agreement with the experimental data.

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Introduction: Rheumatoid arthritis ( RA)is an autoimmune and inflammatory disease. It is characterized by arthrosynovitis with resultant joint destruction . So, an early clinical diagnosis along with simple serological tests like anti CCP antibodies, C –reactive protein ( CRP) and Rheumatoid factor (RF) play an important role .An attempt was made to study and compare these parameters in OPD and IPD RA patients in our hospital setup, VMMC and Safdarjung Hospital , New Delhi. Aims and Objectives: To study the role of RF , Anti-CCP antibodies and CRP in early detection and prognosis of Rheu- matoid arthritis. Materials and Methods: A Total of 440 samples were studied from January 2018 to December 2020 (3years). Correlation between Rheumatoid factor(RF) ,anti CCP antibodies and CRP in suspected RA patients from various departments like PMR , Orthopaedics , Medicine, Obstetrics and Gynaecology and Paediatrics was attempted. RF and CRP was performed using latex agglutination test and anti CCP antibody by ELISA. Results and Conclusion: Of 440 samples tested, all the factors were positive in 87 patients . Anti CCP and RF alone was seen in 32 patients. RF and CRP positive in 49 patients, RF alone in 22 patients. In 250 patients all the tests were negative. So, Anti CCP along with RF and CRP showed a better positive predictive value in patients of Rheumatoid arthritis. But positivity of these parameters even in patients who lack sign and symptoms also aids in better diagnosis, treatment and prognosis.

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There is a need to develop a universal vaccine that can boost immunity to coronaviruses if some modifications in their structure occur. This is what we are dealing with nowadays: a virus that can mutate its structure, while immunity is standing still in facing the virus. We report on preclinical trials of CRCx 3 and CRCx 2 vaccine candidates in inducing an elevated level of positive neutralizing antibodies as well as a cellular immune response in an animal model to provide protection against SARS-CoV-2. Highly efficient protection against SARS-CoV-2 was obtained with three-dose immunization using 0.25 ml of CRCx vaccine with a 25-mm needle at 7-day intervals between successive injections. In addition, CRCx vaccine candidates exhibit efficient productivity and good genetic stability for vaccine manufacture. These results support the further evaluation of CRCx in a clinical trial.

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COVID-19 is caused by SARS-CoV-2 and is associated with the increasing number of cases and deaths and has been declared a pandemic by WHO. The treatment strategy focused on preventing the S protein from binding and penetrating the ACE-2 receptor. In addition, S protein-related molecules such as peptides, blockers, and inhibitors that inhibit S protein cleavage are considered candidate therapeutics.

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This retrospective study was conducted at the Physical Examination Center of the First Hospital of Jilin University, China. The 5594 healthy individuals were included based on strict predefined inclusion and exclusion criteria from 8821 participants who received health examinations between January 2019 and April 2019. H. pylori infection was detected using a commercial carbon-14 urea breath test. Logistic regression analysis was used to determine the relationships of biomarkers of early kidney dysfunction with H. pylori infection, after adjusting for age, sex, and metabolic factors.

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The emergence of SARS-CoV-2 has resulted in > 36,361,054 infections and > 1,056,186 deaths worldwide. Using publicly available genome sequences of patient samples from different geographical regions, a study has been conducted to co-relate mutational frequency with disease transmission and fatality rate.

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In 2016 a very powerful AI (artificial intelligence) tool has been established for predicting sumoylation sites in proteins, one of the most important post modifications in proteins [1].

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Immunodepletion of high-abundant proteins (HAPs) aids in the identification and analysis of low-abundant proteins (LAPs) in complex samples. Currently, immunodepletion methods for bovine samples are very limited whereas greater availability exists for human and murine animal samples. In this study, we report the simultaneous depletion of HAPs from bovine samples using an immunoaffinity depletion cartridge (the multiple affinity removal system, MARS) designed to target six human HAPs, while such a depletion kit for bovine samples is not available.

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Culture characteristics, routine staining for light microscopy and feeding behavior of Voromonas pontica Cavalier-Smith (American Type Culture Collection, ATCC 50640), a predatory free-living marine colpodellid, was investigated

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This study aimed to determine the protein intake and percentage of organ weight in broilers fed rations containing fermented leaves and seeds from the rubber tree (FLSRT) as a substitute for soybean meal. The results of this study are also expected to reduce the use of imported feed ingredients and feed ingredients that compete with human needs, such as soybean meal.

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Bronchial-Asthma, Adhatoda-vasica, In-Silico, IL- 13, IL- 4

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Fish protein concentrated of Silver carp minced, was obtained in three steps using solvent (Isopropanol), drying and pressing using dry temperature (60 °C), and this concentrate had 93% protein, which according to Aquatic protein sources have a high nutritional value and are used to enrich other food products.

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