Articles Related to Proteomics
Immunodepletion of Multiple High-Abundant Proteins from Bovine Fluids
Immunodepletion of high-abundant proteins (HAPs) aids in the identification and analysis of low-abundant proteins (LAPs) in complex
samples. Currently, immunodepletion methods for bovine samples are very limited whereas greater availability exists for human and
murine animal samples. In this study, we report the simultaneous depletion of HAPs from bovine samples using an immunoaffinity
depletion cartridge (the multiple affinity removal system, MARS) designed to target six human HAPs, while such a depletion kit for
bovine samples is not available.
Differential Expression of Proteins Associated with Chronic Hepatitis B Virus Infection on HeLa cell lines
Treatment of Hepatitis B infection is available with the help of existing drugs but the eradication of HBV infection is still under the pipeline. The application of novel drugs and gene-based therapies for HBV infection in need of the hour, however, the lack of efficient cell culture system, animal models for viral infection and replication acts as a major obstacle for novel therapies. This not only hampers the progress of HBV research but also stress the need for effective forthcoming therapeutics for Hepatitis B infection. Proteomic studies to
understand the protein ubiquitination and to find molecular markers are the effective tools to study the HBV infection, pathogenesis and its control.
Proteomic Analysis in Response to Germination in Ceiba pentandra (Kapok) Seeds
1-D, 2-D gel electrophoresis, mass spectrometry and bioinformatics analysis were established and utilized to examine the changes in protein expressions associated with germination of Ceiba pentandra seeds.The change in protein pattern was analysed by 1-D and 2-D gel electrophoresis for better separation and to ascertain the pattern of protein mobilization during germination.
Microwave and Magnetic (M2 ) Proteomics of Childhood B-ALL
We hypothesized that quantitative tandem mass spectrometry-based proteomics, incorporating rapid microwave and magnetic sample preparation (M2 proteomics), might enable relative protein expression to be correlated to childhood B-precursor acute lymphoblastic leukemia (B-ALL) cytogenetic subtypes, corresponding to low-risk (ETV6-RUNX1) and high-risk (MLL-R) subtypes.
Proteomics in Diagnosis: Past, Present and Future
In the post genomic era when several proteomes are on the verge of completion, promising field of protein based diagnostic techniques is emerging. Although protein detection have been used for a long time in clinical diagnostic test, yet high throughput proteomics approaches along with systems biology could be a step forward, towards the development of next generation diagnostic tools and pave a way for personalized medicine.
Editorial Board Members Related to Proteomics
Kwang-Hyun Baek
Department of Biomedical Science
CHA University
Republic of Korea
CHA University
Republic of Korea
Guohui Li
Adjunct Assistant Scientist
Department of chemistry
University of Florida
USA
Department of chemistry
University of Florida
USA
MICHAEL H. A. ROEHRL
Associate Professor
Department of Laboratory Medicine and Pathobiology
University of Toronto
Canada
Department of Laboratory Medicine and Pathobiology
University of Toronto
Canada
Jian Zhu
Assistant Professor
Department of Biochemistry and Biophysics
University of Rochester Medical Center
United States
Department of Biochemistry and Biophysics
University of Rochester Medical Center
United States
CODY P. COYNE
Professor
Department of Basic Science
Mississippi State University
United States
Department of Basic Science
Mississippi State University
United States
Gam Lay Harn
Professor
School of Pharmaceutical Sciences
Universiti Sains Malaysia
Malaysia
School of Pharmaceutical Sciences
Universiti Sains Malaysia
Malaysia
Hong-Wen Deng
Professor
Department of Biostatistics and Bioinformatics
Tulane University
United States
Department of Biostatistics and Bioinformatics
Tulane University
United States
Eva Mischak-Weissinger
Professor
Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation
Hannover Medical School
Germany
Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation
Hannover Medical School
Germany
Fa-Yun Che
Associate Professor
Department of Pathology
Albert Einstein College of Medicine
United States
Department of Pathology
Albert Einstein College of Medicine
United States
Ngai Sai Ming
Associate Professor
School of Life Sciences
The Chinese University of Hong Kong
Hong Kong
School of Life Sciences
The Chinese University of Hong Kong
Hong Kong