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Articles Related to Proteomics

Immunodepletion of Multiple High-Abundant Proteins from Bovine Fluids

Immunodepletion of high-abundant proteins (HAPs) aids in the identification and analysis of low-abundant proteins (LAPs) in complex samples. Currently, immunodepletion methods for bovine samples are very limited whereas greater availability exists for human and murine animal samples. In this study, we report the simultaneous depletion of HAPs from bovine samples using an immunoaffinity depletion cartridge (the multiple affinity removal system, MARS) designed to target six human HAPs, while such a depletion kit for bovine samples is not available.
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Differential Expression of Proteins Associated with Chronic Hepatitis B Virus Infection on HeLa cell lines

Treatment of Hepatitis B infection is available with the help of existing drugs but the eradication of HBV infection is still under the pipeline. The application of novel drugs and gene-based therapies for HBV infection in need of the hour, however, the lack of efficient cell culture system, animal models for viral infection and replication acts as a major obstacle for novel therapies. This not only hampers the progress of HBV research but also stress the need for effective forthcoming therapeutics for Hepatitis B infection. Proteomic studies to understand the protein ubiquitination and to find molecular markers are the effective tools to study the HBV infection, pathogenesis and its control.
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Proteomic Analysis in Response to Germination in Ceiba pentandra (Kapok) Seeds

1-D, 2-D gel electrophoresis, mass spectrometry and bioinformatics analysis were established and utilized to examine the changes in protein expressions associated with germination of Ceiba pentandra seeds.The change in protein pattern was analysed by 1-D and 2-D gel electrophoresis for better separation and to ascertain the pattern of protein mobilization during germination.
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Microwave and Magnetic (M2 ) Proteomics of Childhood B-ALL

We hypothesized that quantitative tandem mass spectrometry-based proteomics, incorporating rapid microwave and magnetic sample preparation (M2 proteomics), might enable relative protein expression to be correlated to childhood B-precursor acute lymphoblastic leukemia (B-ALL) cytogenetic subtypes, corresponding to low-risk (ETV6-RUNX1) and high-risk (MLL-R) subtypes.
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Proteomics in Diagnosis: Past, Present and Future

In the post genomic era when several proteomes are on the verge of completion, promising field of protein based diagnostic techniques is emerging. Although protein detection have been used for a long time in clinical diagnostic test, yet high throughput proteomics approaches along with systems biology could be a step forward, towards the development of next generation diagnostic tools and pave a way for personalized medicine.
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Editorial Board Members Related to Proteomics

Ngai Sai Ming

Associate Professor
School of Life Sciences
The Chinese University of Hong Kong
Hong Kong

Fa-Yun Che

Associate Professor
Department of Pathology
Albert Einstein College of Medicine
United States

Viorica Lopez-Avila

Research Scientist
Agilent Technologies
United States

Yue Chen

Assistant Professor
Department of Biochemistry, Molecular Biology and Biophysics,
University of Minnesota
United States

LOUISA B. TABATABAI

Professor
Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology
Iowa State University
United States

Eva Mischak-Weissinger

Professor
Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation
Hannover Medical School
Germany

Shen Hu

Associate Professor
School of Dentistry
University of California at Los Angeles
United States

Shen Hu

Associate Professor
School of Dentistry
University of California
United States

Andrew Percy

Genome BC Proteomics Centre
University of Victoria
Canada

Julie Teruya-Feldstein

Director
Hematopathology
Immunohistochemistry Laboratory
United States
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