Articles Related to RH

Supraventricular tachycardia is the most common type of tachyarrhythmia seen in childhood. First-line treatments (adenosine, esmolol-propranolol, digoxin, electrical cardioversion) usually suppress tachycardia, but rarely tachycardia is resistant and requiring Class IC and/or Class III agents, such as amiodarone, sotalol, propafenone, and flecainide.

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Cardiac myxoma are the most common primary heart tumor. It accounts for 40-50% of primary cardiac tumor. Approximately 75% occurs in left atrium and 15-20% in right atrium. Myxoma are usually polypoid, pedunculated lesion with smooth surface covered with thrombus. Most common site of attachment is at the border of fossa ovalis in left atrium but it can occur in any part of atrial wall. Symptoms are produced because of mechanical obstruction with cardiac blood flow, tumor embolization and constitutional symptoms due to increased expressions of IL-6. Echocardiography is the best diagnostic modality to localise the tumor. Surgical excision is the mainstay of treatment of myxoma present in any location.

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Intracranial hemorrhage (ICH) is a life-threatening complication in hemophilia. It often occurs during childhood after minimal head trauma. It poses a problem of diagnostic and therapeutic management, especially in Africa where CFCs are not always available.

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Dysbiosis is microbial imbalance and mostly common in gastrointestinal tract [1]. There is a significant different of microbial communities in diarrheic cases more than healthy dogs’ comparison of gender & clinical signs. Clostridium species is mostly commonly genus found infectious animal cases of diarrhea and moreover in dog in other hand unclassified genus of Ruminococcaceae Bacteroidetes and Faecali bacterium were isolated. The microbiome functional gene content of (PICRUSt) with elevation gastric enzymes & increase titers infra structural proteins in acute diarrhea. Studies and data for dysbiosis with different intestinal disorders in dog associated with acute diarrhea or chronic is very limited. Current study to evaluate microbial dysbiosis. The fecal microbiome, characterized by 655 pyrosequencing of the different genes, AU/CG. There was lower range of bacterial isolates from cases of acute diarrhea compared to animal variation with statistical analysis. Altered microbial imbalance in gut occur with the microbial communities for gastric infection.

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Among patients with tuberculosis (TB), approximately 1 to 5 percent develop central nervous system (CNS) complications. A tuberculoma is a conglomerate granulomatous focus that develops from coalescing tubercles acquired during disseminated bacillaemia. Radiographically, tuberculomas are discrete, ring- enhancing lesions of the brain surrounded by perilesional edema and may present as single or multiple lesions. The diagnosis of tuberculoma should be suspected in patients with mass lesion of the brain and relevant epidemiologic factors. A definitive diagnosis of tuberculoma is established via needle biopsy of the CNS lesion for histopathology and acid-fast bacilli (AFB) staining and culture. In this case report, we present a 43-year-old woman with a past medical history of rheumatoid arthritis (RA) managed with steroids and hydroxychloroquine, who attended to us with a two- month history of numbness and paresthesia of her left extremities and recurrent episodic jerks involving the same side. Brain magnetic resonance imaging (MRI) revealed a large hemorrhagic mass (55 * 40 mm) in right temporo-parietal lobe surrounded by edema and mass effect with small nodule in left peri Rolandic cortex. Following clinical and laboratory clues, MR spectroscopy and brain biopsy, we started with corticosteroids and the following 4 anti-TB drugs: Isoniazid, Rifampin, Pyrazinamide, Ethambutol (HRZE). After 2 months, her symptoms completely resolved and a subsequent MRI scan revealed considerable shrinkage of the right-sided mass and left-sided lesion.

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Introduction: Rheumatoid arthritis ( RA)is an autoimmune and inflammatory disease. It is characterized by arthrosynovitis with resultant joint destruction . So, an early clinical diagnosis along with simple serological tests like anti CCP antibodies, C –reactive protein ( CRP) and Rheumatoid factor (RF) play an important role .An attempt was made to study and compare these parameters in OPD and IPD RA patients in our hospital setup, VMMC and Safdarjung Hospital , New Delhi. Aims and Objectives: To study the role of RF , Anti-CCP antibodies and CRP in early detection and prognosis of Rheu- matoid arthritis. Materials and Methods: A Total of 440 samples were studied from January 2018 to December 2020 (3years). Correlation between Rheumatoid factor(RF) ,anti CCP antibodies and CRP in suspected RA patients from various departments like PMR , Orthopaedics , Medicine, Obstetrics and Gynaecology and Paediatrics was attempted. RF and CRP was performed using latex agglutination test and anti CCP antibody by ELISA. Results and Conclusion: Of 440 samples tested, all the factors were positive in 87 patients . Anti CCP and RF alone was seen in 32 patients. RF and CRP positive in 49 patients, RF alone in 22 patients. In 250 patients all the tests were negative. So, Anti CCP along with RF and CRP showed a better positive predictive value in patients of Rheumatoid arthritis. But positivity of these parameters even in patients who lack sign and symptoms also aids in better diagnosis, treatment and prognosis.

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Dengue is a prevalent arthropod-borne viral disease in tropical and subtropical areas of the globe. Dengue clinical manifestations include asymptomatic infections; undifferentiated fever; dengue fever, which is characterized by fever, headache, retro orbital pain, myalgia, and arthralgia; and a severe form of the disease denominated dengue hemorrhagic fever/dengue shock syndrome, characterized by hemoconcentration, thrombocytopenia, and bleeding tendency. However, atypical manifestations, such as liver, central nervous system, and cardiac involvement, have been increasingly reported called expanded dengue syndrome. The renal complications of dengue virus infection cover a wide spectrum of manifestations from acute kidney injury to glomerular injury with nephritic/nephrotic syndrome. Majority of cases remain symptom free and show full recovery. We report a 55 years old lady with atypical and rare presentation of dengue disease marked by rapidly progressive glomerulonephritis. Condition improved after initial 5 days pulse methylprednisolone followed by oral prednisolone therapy and mycophenolate mofetil. The main mechanism of dengue glomerulonephritis is still unknown though both direct viral infection and immune mediated damage have been suggested to be the cause. To avoid otherwise preventable morbidity and mortality, physicians should have a high index of suspicion for renal complications in patients with dengue illness and should manage this accordingly

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Erdhein-chester disease is a rare non-Langerhans histocytes that can involve multiple systems, with bone involvement as the most common. We reports a 39-year-old female who visited the hospital due to pain in both lower limbs, combined with clinical manifestations, imaging, and laboratory tests, Erdhein-Chester disease was prelimi narily diagnosed. The diagnosis was confirmed by the presence of BRAF V600E mutation and tissue cells on biopsy of the right tibia. We discussed the disease based on literature review, aiming to improve the understanding of clinicians.

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Diarrhoea is a common and diverse aetiology problem in HIV infected patients that can cause deterioration in the quality of life, malnutrition and failure of antiretroviral therapy (ART). Ibalizumab (IBA), a humanized monoclonal antibody that binds to domain 2 of CD4 T lymphocytes receptor, has been recently approved for treating adults infected with multidrug-resistant HIV-1 infection for whom it is otherwise not possible to construct a suppressive antiviral regimen.

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: Colporrhexis is separation of vaginal fornix from cervix and is a rare but serious cause of major obstetric haemorrhage in women during labor. Immediate clinical diagnosis is difficult but must be anticipated if haemorrhage continues despite contracted uterus following delivery. Rapid resuscitation and decision of laparotomy with either repair or hysterectomy is key in preventing maternal mortality.

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Exclusive breastfeeding is essential for the first 6 months of life. In Pakistan, the proportion of children under age 6 months who are exclusively breastfed is only 38 percent making it urgent to explore interventions to address the low rates.

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Bosma arrhinia microphthalmia syndrome is a rare entity of unknown etiology, characterized by abnormalities of the nose and eyes and hypogonadotropic hypogonadism.

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Anti-streptolysin O (ASO) titer assists for the diagnosis of streptococcal infections and their sequele. Normal value of Anti-streptolysin O titer is not available for Ethiopian populations. These studies establishes and compare the normal reference value in Rheumatoid Heart Disease (RHD) and in apparently healthy children.

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Crouzon syndrome is an autosomal dominant disorder characterized by fusion of coronal and sagittal sutures. There is arrested growth of the maxilla and zygoma resulting in shallow orbits with ocular proptosis, hypertelorism and maxillary hypoplasia. Hereby, we present a case report of a 20-year-old Jamaican female with Crouzon syndrome, who had multiple facial deformities including midfacial hypoplasia, short upper lip and hypertelorism.

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Culture characteristics, routine staining for light microscopy and feeding behavior of Voromonas pontica Cavalier-Smith (American Type Culture Collection, ATCC 50640), a predatory free-living marine colpodellid, was investigated

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