Articles Related to ROC
Reducing Toxic Constituents of Ginkgolic Acids Content and Improving Bioactive Flavonoids Content from Ginkgo Biloba Leaves by High Temperature Pretreatment Processing
High temperature pretreatment was developed in this article to remove the main toxic constituents of ginkgolic acids
(GAs) from Ginkgo biloba leaves (GBLs) and improve the bioactive flavonoids content by water extraction. To optimize
the effects of high temperature pretreatment process parameters on removing toxic GAs to the limited level and improving
content of bioactive flavonoids, a Box-Behnken design (BBD) combined with response surface methodology (RSM) was
also conducted. The results showed that the content of GAs could be reduced to 4.11 ppm and the highest content of flavonoids could reach 3.51 % under the optimized conditions of high temperature pretreatment process of 177 °C with water
extraction at 96 °C at a liquid-to-solid ratio of 56:1. The content of toxic GAs substantially decreased by 83.50% while the
content of bioactive flavonoids increased by 44.30% compared with the conventional water extraction method. Moreover,
the new process was more efficient, environmentally friendly and could get avoid of a subsequent multi-step process of
removing toxic GAs. The crude extracts were then purified by macroporous resin to obtain the 60% ethanol fraction. After
purification, the flavonoids content increased to 43.50% while the GAs were not detected. The main compounds of 60%
ethanol fraction were identified by UPLC-QTOF-MS/MS. Antioxidant activities including reducing powder, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, and OH· scavenging assays all showed that the 60% ethanol fraction was
better than the butylated hydroxytoluene (BHT) standard.
Rare Adnexal Carcinomas: Series of Four Cases Treated at the Ibn Rochd University Hospital of Casablanca
Cutaneous adnexal carcinomas are rare cutaneous malignant adnexal tumors derived from eccrine and apocrine sweat glands, follicular structures and sebaceous glands. They represent less than 1% of cutaneous cancers Porocarcinoma and hidradenocarcinoma are two main types of eccrine sweat carcinomas of unknown pathogenesis
characterized by their clinicopathological diversity.
A Controlled Release PLGA Bupivacaine Construct and its Effect on Chondrocytes
Controlling osteoarthritic pain has emerged as a major health care challenge. Available treatments are either cytotoxic or addictive and therefore there is an urgent need to develop alternative treatment options. We previously developed a liposomal-alginate construct to improve local anesthetic delivery as a potential chronic pain management treatment.
Formulation and In-vitro Characterization of Fluoxetine Hydrochloride Loaded Fast Dissolving Oral Film Using HPMC 15CPS and HPMC K4M
Fluoxetine Hydrochloride (FH), a selective serotonin reuptake inhibitor (SSRI) is a drug of choice in depression, obsessive-compulsive disorder (OCD), bulimia nervosa, etc. Though tablet, capsules, oral solution, or syrup are currently available conventional dosage form of FH, modified or immediate-release formulations for fast onset of action is of utmost importance.
Assessment of Cyanide Concentrations in Cassava Peels obtained at different levels of Processing for Resource Reuse
Cassava processing is a year-round activity in Nigeria, especially in southern part and Ibadan city. The wastes generated by the various processing industries are enormous. Cassava peels are a major residue of processing to prepare various food products. The cassava peels have high concentration of cyanide which has toxic and polluting effects. It is therefore important that the peels are properly processed or pre-treated to reduce the cyanide content before using them as livestock feed which is a common practice among livestock rearers.
HIV Screening Scenarios and Targets to Achieve 90% Sero-Status Knowledge Over 2021-2025 in Morocco – Pioneer Use Case of the Goals HIV Testing Strategies Model in a Concentrated Epidemic
Morocco applied the Goals testing model, projecting alternative testing scale-up scenarios, varying coverage targets for 13 adult populations. The model was calibrated using program service delivery, spending and surveillance data (2015-2019), integrated bio-behavioural surveys, and national HIV estimates. It projects annual diagnoses by target group from undiagnosed prevalence and testing coverage, allowing for HIV-infected people self-selecting for testing, retesting and transitions between groups. Scenarios were
evaluated for knowledge status improvement and cost, focusing on 2023-2025.
Nightmare Case of Complex Neonatal Truncus Arteriosus
Neonatal management of severe quadricuspid truncal valve insufficiency is very challenging with high risk of postoperative mortality. Aortic valve reconstruction is the unique rescue and should be consider and previously planned in case of truncal valvuloplasty failure. Many extracardiac malformations can be associated with truncus arteriosus, therefore a cardiac and chest computed tomography scan must be performed before the elective surgical repair.
Effect of the Seasons on the Change of Morphological, Histo-Cytological and Hormonal Parameters of the Thyroid Gland in Cattle in Algeria
This study was carried out to study the peculiarities of the topography, the macrostructure and the analysis of the structural and functional organization patterns of the parenchyma of the thyroid gland of dairy cows (local breed from the Souk Ahras region, Algeria). A complex of macroscopic and histological techniques was used, as well as immunohistochemical staining of thyroid gland sections to identify localization characteristics of thyrocyte populations in the parenchyma.
Utilization of Red mud-Water/Soil Pollutant for Alternative Engineering Applications: A Critical Perspective Review
Environmental pollution and climate change continue to be a major cause for concern in the 21st century. Aluminum is the most abundant metal on the surface used in every walk of life. Red mud, a by-product produced during the extraction of Aluminium from Bauxite by Bayer’s Process, causes serious hazards for the human and ecological systems.
Formulation and Evaluation of Sustained Occular Delivery of Ciprofloxacin Hydrochloride
The aim of the present work was formulation and evaluation of in-situ gelling system of Ciprofloxacin Hydrochloride. The poor
bioavailability and therapeutic response exhibited by conventional ophthalmic solution due to rapid precorneal elimination of the drug
may be overcomed by the use of in-situ gel forming system that are installed as drop into the eye and undergo sol to gel transition in the
cul-de-sac.
The First Suspicions Case of Congeneital Microcephaly Associated with Zika Virus in Eastern Democratic Republic of Congo
Zika virus infection is public health emergency in the world with 4 million people infected in America.The objective of
this presentation is to recall and illustrate the fetal microcephaly associated to Zika virus infection in pregnancy
Greater Trochanter Avulsion Associated with Posterior Hip Dislocation
Hip dislocation occurs when axial loading force is transmitted through intact femoral shaft to the hip joint leading to a posterior dislocation of the femoral head with or without posterior acetabular fracture. However dislocation of the hip with associated fracture of the trochanter, neck or shaft of femur is uncommon in literature. We present the case of a 56 year old patient who fell from a height. Clinical and imaging [radiography, CT] examination revealed a comminuted greater trochanteric fracture associated with ipsilateral posterior hip dislocation.
Changing of Charge Carriers Concentration in a Diffusion-Junction Rectifier with Variation of Radiation Processing of Materials
In this paper we analyzed changing of dynamics of redistribution of dopant during manufacturing of diffusion-junction rectifier in a
heterostructure due to radiation processing.
Setting Threshold Value for Peripheral Blood Morphology Slide Review of Leucocytes and Lymphocytes at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia
Evaluation of peripheral blood morphology is an important screening tool for many diseases.
The Relationship of Visuo-Motor Processing and Upright Balance in Acutely Concussed Athletes
Following a concussion, athletes display impairments in upright balance, as well as changes in visual acuity. Balance deficits arise as a result of sensory information integration impartments when sensory information processing is delayed or altered. Investigating the relationship between visual processing and balance following a concussion will help to better understand the underlying pathophysiologic mechanisms for balance deficits and why altered visuo-motor processing may be related to postural instability.
Ordered Growth of Anodic Aluminum Oxide in Galvanostatic and Galvanostatic-Potentiostatic Modes
The results are presented of obtaining anodic aluminum oxide with an ordered pore arrangement by employing two anodizing modes - galvanostatic mode and combined (galvanostatic + potentiostatic) mode, at high values of the current density and voltage. Use has been made of an oxalate electrolyte and a complex electrolyte comprising oxalic acid and phosphoric acid. Scanning electron microscopy has been used to investigate the surface morphology of the barrier and porous layers and to determine pore sizes and inter-pore distance.
Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS
The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in
legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine
the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix),
polyester, rayon and wool.
The Effects of the Film Thickness and Roughness in the Anodization Process of Very Thin Aluminum Films
The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.
Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell
The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
Editorial Board Members Related to ROC

Zezhang Tom Wen
Associate Professor
School of Medicine
LSU Health Sciences Center School of Dentistry
United States
School of Medicine
LSU Health Sciences Center School of Dentistry
United States

Joseph Prandota
Emeritus Full Professor
Department of Pediatrics & Clinical Pharmacology
Faculty of Health Sciences
Wroclaw Medical University
Wroclaw
Poland
Department of Pediatrics & Clinical Pharmacology
Faculty of Health Sciences
Wroclaw Medical University
Wroclaw
Poland

MICHAEL P. SHERMAN
Professor Emeritus
Department of Child Health
Division of Neonatology
University of California-Davis School of Medicine
United States
Department of Child Health
Division of Neonatology
University of California-Davis School of Medicine
United States

Jun Ni
Associate Professor
Department of Radiology
Carver College of Medicine
University of Iowa
United States
Department of Radiology
Carver College of Medicine
University of Iowa
United States

Bruno Amato
Associate Professor
Department of Clinical Medecine and Surgery
University Federico II of Naples
Italy
Department of Clinical Medecine and Surgery
University Federico II of Naples
Italy