Articles Related to RT

Objective: The purpose of this study was to compare the bioavalability between the two 80 mg Valsartan Tablets formulations and to evaluate the bioequivalence of Reference and Test formulations of Valsartan Tablets 80 mg in Healthy adult chinese Male and Female subjects under Fasting and Fed condition.

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This paper covers the validation and measurement uncertainty evaluation of an ICP-AES method for bismuth mass fraction determination in bismuth sulfide thin films. Plasma view at radial mode and the wavelength were monitored for bismuth at 223.061 nm. Following AFNOR (Association Française de Normalisation) Norm NFT 90-210 (2009), a regression equation was calculated using single element bismuth standard solution prepared in the same matrix as samples. The linear range was between 0.2 and 2.0 mg L−1. Limits of detection (LOD) and quantification (LOQ) were calculated as 0.03 and 0.12 mg L−1, respectively. Recovery percentages were ranging between 91 and 109 %. Accuracy was found to be adequate. Estimated expanded uncertainty according to both GUM and EURACHEM guides was 3.1 %.

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Background: Manifold emulsions are used to increase the bioavailability of active medicinal ingredients and to provide a longer drug delivery mechanism. Hydrophobic and hydrophilic combinational surfactants are frequently used to stabilize the manifold emulsions.

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This study is an attempt to emphasize the prevalence of severe anemia in pediatric age group and characterize different clinical and Hematological findings among them. Anemia is a major global health problem, especially in developing countries like India, despite the fact that this problem is largely preventable & easily treatable. It leads to morbidity and mortality in children and establish a public health problem of substantial importance.

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Intracranial hemorrhage (ICH) is a life-threatening complication in hemophilia. It often occurs during childhood after minimal head trauma. It poses a problem of diagnostic and therapeutic management, especially in Africa where CFCs are not always available.

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Background: Super capsular percutaneously-assisted total hip (Super PATH) approach has been regarded as one of minimally invasive and muscle sparing technique, which accesses the hip maintaining integrity of the external rotators and capsule. The purpose of this study was to compare the Super PATH approach with the conventional posterolateral approach in terms of early clinical outcomes and radiological results.

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Proper use of medicine or taking medicine in correct order is essential to cure any disease. According to the WHO, lack of adherence to treatment regimens leads to major problems among patients, mostly with chronic illnesses

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The present work aims to study a convenient and environmentally friendly method for the green synth of silver nanoparticles (AgNPs based on lemon juice extract. The biomolecules contained in lemon extract act as self- reducing and stabilizing agents. The optimal solution for the synthesis of AgNPs was determined by varying silver nitrate concentrations. A surface plasmon resonance system identified the synthesized silver nanoparticles by their color change from colorless to dark brown. Silver nanoparticles synthesized were characterized by Uv-visible (UV-Vis) spectroscopy, high-resolution transmission electron microscopy (HR-TEM), and FTIR spectroscopy. As a result of UV-visible spectroscopy, surface plasmon resonance (SPR) can be determine

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Hydranencephaly is an extremely rare congenital anomaly of the central nervous system, characterized by the almost total absence of the bilateral cerebral hemispheres and replaced by cerebrospinal fluid. Almost all cases are sporadic with an incidence of less than 1 per 10,000 births and a very poor prognosis. The exact main cause is still unknown, but hydranencephaly is usually found to develop secondarily to the occlusion of cerebral arteries above the supraclinoid level. We report the case of a full-term female infant with hydranencephaly diagnosed at 28 weeks of gestation by routine antenatal intrauterine ultrasonograph

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Objective: Obstructive sleep apnea (OSA) is a highly prevalent disease associated with various morbidities worldwide. Although continuous positive airway pressure (CPAP) is the cornerstone of therapy, adherence to CPAP directly affects its efficacy. Methods: We retrospectively investigated consecutive patients who were diagnosed with OSA and placed on CPAP the- rapy within an approximate ten-year period. Using patient characteristics and short-term usage, the predictors of adhe- rence to CPAP were evaluated.

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The study assessed factors affecting fertilizer applications by yam farmers in Edo State, Nigeria. The specific objectives were to: ascertain the basic source of information among the farmers, determine the factors affecting fertilizer applications on yam production and the constraints working against yam production in the study area. Multistage sampling techniques were used in this study.

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The European Association of Urology currently recommends partial nephrectomy as the preferred management for localised cT1 renal tumours, irrespective of surgical approach. With the advent of robotic assisted partial nephrectomy, there is growing evidence that warm ischaemia time may be reduced compared to the traditional laparoscopic approach.

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Necrotizing Sialometaplasia (NSM) is a rare, benign, self-limiting, inflammatory disease of mostly minor salivary gland origin. NSM can resemble a malignant lesion in its early disease course, both clinically and pathologically. Bilateral involvement of the hard and soft palate by the lesion is a rare occurrence. NSM was first described as a reactive inflammatory process. Since then, over 200 cases have been reported and has been added to the WHO classification of salivary gland tumours under the tumour-like lesions. Here, we report a case of a 30-year-old male with bilateral NSM of both the hard and soft palate, on a background history of prurigo nodularis. The patient was initially referred to an Oral and Maxillofacial Department by his general practitioner for a palatal ulcer, concerning for oral malignancy. The ulcer was painless with a well-demarcated border and necrotic base. Subsequent biopsy and histological examination confirmed necrotizing sialometaplasia with healing occurring within 5 weeks.

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Background: Morocco is a low endemic country of HIV/AIDS that achieved the goal of the second and third 90-90-90 targets in 2019 while still 78% of people living with HIV know their HIV status. The aim of this study was to analyze time trends of HIV/AIDS reported cases during the last 33 years taking into consideration the implementation of voluntary HIV counseling and testing (HCT) services in primary health care facilities. Methodology: This was a time series of HIV/AIDS reported cases at national level between 1986 and 2019. Variable collected for each year were HIV/AIDS reported per 100000 H, age category, gender, origin, CD4 count and route of transmission. Trend of HIV/AIDS reported cases was assessed by Joinpoint Regression Analysis. Annual percentage changes (APCs) were estimated to identify the years (joinpoint) when significant changes occurred in the trend. We therefore examined trends in HIV/AIDS reported cases according to epidemiological variables. Results: Cumulative HIV/AIDS reported cases during the study period was of 17 000. Joinpoint regression showed an increase in HIV/AIDS reported cases between 1986 and 2019. The APC for the period 1986-2012 was of 13.4 (95% CI: 12.0 to 14.8, p <0.05) and the APC from 2012 to 019 was of 5.4 (95% CI: 2.5 to 8.5, p<0.05) with a significant break in the same joinpoint year than HCT implementation in primary health care settings. In stratified analysis, HIV/AIDS reported cases increased but not significantly after joinpoint. A significant decrease was noted in 2015 in urban areas (APC = -10.0, 95% CI: -17.0 to -2.3, p<0.05). Conclusions: HIV/AIDS reported cases were increasing over 33 years, with a significant rise after 2012by 5% per year, corresponding to HCT integration into primary health care setting. Furthermore, Morocco is may be on the right way to eliminate HIV/AIDS in urban areas.

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Diabetic macular edema (DME) has become one of the most potential complications that results in loss of vision in patients with diabetic retinopathy. Treatment outcomes that have been predicted directly with advent of machine learning (ML) methods after the initial anti-vascular endothelial growth factor (anti-VEGF) injection, has become extremely vital in the management of DME. Purpose: The aim of this study is to analyze the efficiency of the ML regression models which were developed and validated to predict the possible post-injection central subfield thickness (CST) value and distant vision best corrected visual acuity (DV BCVA) in eyes with DME before the anti-VEGF injection is administered at either treatment initiation or during treatment monitoring. Methods: This retrospective study was conducted in Medical Research Foundation, Chennai, India from January 2010 to December 2020. The model development emphasized on an ensemble ML system consisting of four ML models that were developed and trained independently using the clinical parameters to predict the post injection CST value. The dataset consisting of 906 patients with total of 1874 samples [Optical coherence tomography (OCT) images and clinical parameters] were divided into trained and test set, and the model was validated on test dataset. The predicted CST values was then compared against the respective sample’s post injection actual CST value. The comparative results were measured in terms of Correlation Coefficient and Mean Absolute Relative Error (MARE). Results: On evaluation, we found that Support Vector Regression (SVR) with linear kernel performed best among the other models with four different scenarios in term of both CST and DVBCVA prediction with correlation coefficient of 0.65, 0.73, 0.75, 0.85 and 0.83, 0.87, 0.89 and 0.92 respectively.

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Self-organized anodic porous alumina films with hexagonal pore lattice have attracted a considerable attention for biological arrays and confinement of various organic probes dyes in solutions. A molecular structure with axial symmetry in bis-heterocyclic indole chains and conjugate system, such as cyanine fluorophore Cy3 dye, was investigated here with respect to its fluorescence when loaded in the anodic alumina pores.

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Two basic reactions occur during the anodizing of aluminum: 1) the aluminum is consumed and 2) an oxide grows. By accepting this statement as true, the anodizing process can be viewed as a corrosion process, and anodizing can be modeled using the Tafel Equation. Anodizing process parameters of electrolyte chemistry and concentration, temperature, aluminum substrate resistance and current density are presented as they relate to the Tafel Equation and how they impact the anodic aluminum oxide structure and properties. Understanding this relationship is consequent in making anodizing an engineering process, one that enables tuning the structure such that it yields distinct characteristics to fulfill design and application requirements.

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Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.

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The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.

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Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological samples.

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The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.

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The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.

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Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.

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We investigated a method for preparation of ordered nanopore arrays with the interpore distance of 60 nm by guided self-organization of anodic aluminum oxide with a prepatterned array of pits in the starting Al film.

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The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.

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Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.

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Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.

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In this paper, we report on the synthesis of BaTiO3 nanowires via the anodic aluminum oxide template method. To fill in the precursors of BaTiO3 into anodic aluminum oxide templates, the vacuum and drop loading method developed in our previous study was used. Ba(CH3COO)2 (barium acetate) and C12H28O4Ti (tetraisopropyl orthotitanate) were used as Ba and Ti sources, respectively. Anodic aluminum oxide membranes with the through-hole diameter of ~200 nm were used as the template for BaTiO3 nanowires.

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