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Acute Pneumonia is More Cardiovascular than a Respiratory Disaster

The discovery of antibiotics was one of the greatest achievements of medical science. The introduction of these drugs into medical practice has saved and continues to save millions of lives. At the same time, every year it becomes more and more obvious that antibiotics are not a universal remedy for inflammatory diseases, and their long-term use entails the emergence of new problems
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Epiphyseal Closure of Femur, Tibia and Fibula of the Paca (Cuniculus Paca, Linnaeus, 1766)

After capybara, paca (Cuniculus paca) is the largest rodent in the neotropical region and the body weight varies from 5 to 10 kg, and may reach up to 14 kg. They are animals that reach sexual maturity at around 10 months of age. The aim of this research is to examine, through radiography, the femur, tibia and fibula of the paca. The animals were anaesthetized for radiographic exams. At 6 months of age, the growth line of the femoral proximal epiphysis ceases to perform its functions. At 12 months of age, there is the closure of the line growth of distal femoral epiphysis. At the paca’s tibia, at 12 months old, there was the closure of the growth of the proximal epiphysis. In the distal epiphysis, the closure of the line growth also occurred at 12 months old. At the paca’s fibula, the bone activity of proximal epiphysis ceases with only 23 months old. The distal fibular epiphysis ends its development with 15 months. There are similarities and differences relative to the closure of the pacas’ epiphysis femur, tibia and fibula comparing with dogs and cats.
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Gross and Histopathological Alterations in Experimental Trypanosoma Evansi Infection in Donkeys and the Effect of Isometamidium Chloride Treatment

Trypanosoma evansi (T. evansi) infection causes wasting and fatal animal trypanosomosis. This study was aimed at determining the gross and histopathological alterations in donkeys experimentally infected with T. evansi and the effect of isometamidium chloride treatment. Apparently healthy donkeys (N=18) of mixed sexes were randomly assigned to 3 groups; A1 (Infected-untreated), A2 (Infected, isometamidium-treated) and B (Uninfected, control) of six animals each. Each animal in infected groups had about 2.0x106 T. evansi injected through the jugular vein. Parasitaemia levels were evaluated using HCT and Mice Inoculation Test (support test). Gross and histopathological examinations were also conducted post-infection and post-treatment.
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Epigenetic Changes Caused by Occupational Stress in Humans Revealed through Noninvasive Assessment of DNA Methylation of the Tyrosine Hydroxylase Gene

Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the synthesis of L-dihydroxyphenylalanine (L-DOPA), a precursor of dopamine, and is considered to be involved in many aspects of mental health. On the other hand, the epigenetic mechanisms have been recognized as mediators of stable changes in brain function.
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Microfilaria Causing Bone Marrow Failure

It is common to detect microfilariae in various cytological preparations, however there are very few case reports describing microfilariae in bone marrow aspirates. It is rarer to get bone marrow failure secondary to microfilaria in bone marrow. We report here a patient from Bihar, presented to us with prolonged fever and pancytopenia, bone marrow aspirate showed microfilaria. Treatment with DEC and albendazole resulted in prompt recovery.
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Editorial Board Members Related to SAS

Jamie I. Baum

Assistant Professor
Department of Food Science
University of Arkansas
United States

Cristiana Palmela Pereira

Assistant Professor
Portuguese Institute of Legal Medicine
University of Lisboa
Portugal

Stefan Hiendleder

Professor
JS Davies Fellow Epigenetics and Genetics
Roseworthy Campus, University of Adelaide
Australia

AYMAN ELTAIRY MAHMOUD MAHDY

Associate Professor
Division of Urology
University of Cincinnati
United States

Ramesh C. Gupta

Professor of Chemistry
School of Agricultural Sciences and Rural Development (SASRD)
Nagaland University
India

K. RAMANATHAN

Associate Professor
Industrial Biotechnology Division
School of Bio Sciences and Technology
VIT University
INDIA

MENG-YANG ZHU

Associate Professor
Department of Pharmacology
Quillen College of Medicine
East Tennessee State University
United States

Fernando A. Herrera

Assistant Professor
Department of Surgery
Medical University of South Carolina
United States

Paul H. Wooley

Professor
Orthopaedic Research Institute
Wichita State University
United States

Rostislav Kostadinov

Associate Professor
Disaster Medicine
Medical University Plovdiv
Bulgaria
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