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Non-Polio Enterovirus Meningitis in Children-Clinical Spectrum, Viral Serotypes and Outcome: Unusual Community Outbreak Experience at a Tertiary Care Centre from Oman

Enterovirus meningitis is one of the commonest viruses causing meningitis in children which is underdiagnosed. The epidemiology of EV infections is not well studied in the Middle East and Arab Gulf Region. No Study was conducted in Oman to explore more about viral meningitis. This study will help to review enterovirus meningitis in order to guide management and patient care in Oman and will help to decrease the cost of treatment by avoiding unnecessary investigations.
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Review Article: Managing Spinal Cord Injury on Anesthesiologists’ Perspective

Spinal cord injury (SCI) is trauma to the area of the vertebrae resulting in spinal cord lesions resulting in neurological disorders, depending on the location of the spinal nerve damage and the injured nerve tissue. The symptoms of SCI can range from pain and paralysis to incontinence. SCI due to trauma is estimated to occur in 30-40 per million population per year, and about 8,000- 10,000 sufferers each year; generally, occurs in adolescents and young adults. Although the annual incidence of events is relatively low, the cost of care and rehabilitation for spinal cord injuries is very high, at around US $ 53,000 / patient.
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Hyperbaric Oxygen Therapy Improves Cognition in Patients Severe TBI; A Prospective Study

Cognitive impairment post TBI is an important factor in rehabilitation outcomes. Pharmacological and therapeutic services do not directly address damage to the cortical infrastructure. Hyperbaric Oxygen Therapy is known to improve brain function and healing.
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Characterization of Pugmark for Animal Species Identification for Forensic Importance

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Establishing a Special Open Field Test Appliance for Tree Shrews Evaluates their Stressed Locomotor Behavior

It has a great significance to establish a high repetitive and special system to evaluate locomotion for tree shrew animal models, especially neuropsychiatric models. Thus, we designed a special open field test appliance for tree shrews by using a polymer PMMA board (plexiglass). The locomotion of naïve tree shrews was detected twice in it. By using Any-maze Software tracing the motion trajectory, we found that the motion trajectory and the distance were very similar in both tests. It demonstrated that the appliance designed for tree shrews had extremely high reliability and stability.
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Bioequivalence between Two Capsules of Pirfenidonein Healthy Subjects under Fed Condition

Pirfenidone capsules are indicated for the treatment of patients with Idiopathic pulmonary fibrosis. The Bioavailability of two formulations containing pirfenidone 267 mg hard gelatin capsules was compared in a bioequivalence study under fed conditions. The study was single dose, randomized, open label, two-period crossover, with Brazilian healthy subjects, males and nonpregnant females.
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Cognitive Enhancers Derived from Edible Crops

The concept of an effective cognitive boosting nootropic supplement is gaining traction with consumers, neuroscientists and regulators alike and it is therefore unsurprising that scientifically validated Nootropics are highly prized. New research demonstrates edible crops could be useful sources to mine for new nootropics; plant extracts enriched with an array of cognitive enhancing metabolites. There is merit in investigating these plant species. Metadata has identifies consuming specific fruit and vegetables positively affects cognitive function; therefore these same edible crop plants present as opportunities for developing nootropic formulations. This hypothesis is supported by positive data obtained through clinical testing [e.g. extracts of tomato (Solanum lycopersicum), herbs from the Genus Salvia, cocoa (Theobroma), tea (Camellia sinensisor) and coffee (Coffea Arabica). This review will discuss clinically tested cognitive enhancers derived from edible crop species and discuss their use alongside other classes of nootropics.
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Charles Bonnet Syndrome: Rapid Resolution of Visual Hallucinations with Low Dose Risperidone

Charles Bonnet syndrome (CBS) comprises of complex visual hallucinations secondary to visual impairment in the presence of preserved cognition. Age related macular degeneration and other factors causing visual deterioration lead to visual hallucinations in 10-15% of patients. Sensory deprivation and social isolation are risk factors for development of CBS. The distressing hallucinations are underreported by patients and to date there are no robust evidence based guidelines to manage these hallucinations. Since visual hallucinations are associated with multiple psychiatric disorders as well, these patients are often referred to mental health providers. Here, we present the case of CBS development after macular degeneration. Rapid and sustained resolution of visual hallucinations and associated distress was observed with low dose Risperidone.
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Triphasic Waves in EEG, an Atypical Finding in a Subacute Sclerosing Panencephalitis (SSPE) Adult Patient

Subacute sclerosing panencephalitis (SSPE) is a known rare cause of progressive myoclonic encephalitis of childhood and young adults due to a persistent measles virus infection.
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Forensic Medical Aspect in Siddha Medical System-Comparative Study

Siddha medical system is creating to re-erect of whole world by their facts on human being of health status of living now.
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Bioequivalence between Two Tablets of Levetiracetam in Healthy Subjects under Fasting Condition

Bioavailability of two formulations containing levetiracetam 750 mg film-coated tablets was compared in a fasting bioequivalence study. The study was single dose, randomized, open label, and two-period crossover, with Brazilian healthy subjects, males and nonpregnant females. Blood samples were taken for 36 hours after drug administration and plasmatic concentrations were determined using a validated HPLC-MS/MS method. Confidence intervals (CI90%) for the peak plasma concentration (Cmax) and area under the concentration-time curve (AUC0-t) were determined by calculating LN-transformed data. The ratios and 90% CI for the geometric mean test/reference were 97.41% (91.45- 103.75%) for Cmax and 99.77% (97.07- 102.54%) for AUC0-t.
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Optical Coherence Tomography Angiography for Choroidal Neovascularization and Subretinal Fibrosis in Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is characterized by a progressive fragmentation and calcification of elastic fibers in connective tissue and when Bruch membrane (BM) is affected ocular modifications can be found. Recently, Optical coherence tomography-angiography (OCT-A) contribute to a better comprehension of lesions in PXE.
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Determination of N-Butylscopolamine in Human Plasma by Solid-Phase Extraction and UHPLC-ESI-MS/MS: Development, Validation and Application to a Bioequivalence Study

BioequivalenceA sensitive ultra performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS) method for measurements of N-butylscopolamine in plasma was developed and validated. A SPE extraction was proposed for the clean up of plasma and N-butylscopolamine-d9 was added as internal standard. The analyses were carried out using a phenyl column and mobile phase of acetonitrile:
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MOX Fuel Alternatives for Minor Actinides Burnup in Thermal Spectrum

The spent fuel from the nuclear power reactors is being stored in repositories and dry casks in many countries of the world. However, it does not solve the main problem of the spent fuel, which is the high radiotoxicity of fuel for a long term. A new strategy is required to close the nuclear fuel cycle, and for the sustainability of the nuclear power generation. This strategy could be the plutonium recycling to obtain more energy and recycle the Minor actinides produced during the irradiation, to transmute them into less radioactive products. In this work, we assess the amounts of Minor actinides generated in different fuel designs and the amounts of Minor actinides remaining after recycle them in a thermal reactor.
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Problems of Agriculture in Azerbaijan and the Prospects of its Development

This article examines the current state of soil and water resources, farmland in Azerbaijan Republic, the problem of progressive water and wind soil degradation, the need for the organization of agriculture, taking into account the introduction of automated control systems for irrigation using water saving technology and hardware equipment in it, the study of the characteristics and analysis of experience implementing measures to stabilize ecological and drainage system of agriculture in conditions of insufficient moisture areas in the country, as well as basic aspects of development of environmental reclamation approach balanced, rational use of a particular system of crop rotation and crop taking into account the requirements of economic development and environmental management.
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Introduction to the special issue on ‘Nanostructures by Valve Metal Anodization’

With this special issue of JMSN we are pleased to present significant contributions to a fascinating topic in the field of materials nanostructing, which is the anodization of valve metals. By this treatment porous oxides of controlled geometry can be grown on the respective metal surfaces. To date, aluminum (Al) has been used most often, as confirmed in this special issue where nine out of ten contributions deals with its anodization.
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Recent Developments in Human Odor Detection Technologies

Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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Anodic Oxidation of Titanium in Sulphuric Acid and Phosphoric Acid Electrolytes

Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.
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Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
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Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions

Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
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Editorial Board Members Related to SPE

Hongxia Hao

Lecturer
Department of Chemistry
University of Toronto
Canada

Zhiping Yu

Assistant Professor
Department of Nutrition and Dietetics
University of North Florida
United States

Mohamed Eddouoks

Professor
Faculty of Sciences and Techniques Errachidia
Moulay Ismail University
Morocco

Shirley Mcilvenny

Professor
Department of Health and Nutrition
National Institute of Integrative Medicine
Australia

Jorge Cerezal Garrido

Associate Professor
Department of Surgery
Medical school of the University Miguel Hernandez
Spain

Mohsen Meydani

Professor
Friedman School of Nutrition Science and Policy
Tufts University
United States

Yinghao Wu

Assistant Professor
Department of Systems & Computational Biology
Yeshiva University
United States

Metin Kilinc

Professor
Department of Medical Biochemistry
Kahramanmaras Sutcu Imam University
Faculty of Medicine
Kahramanmaras, Turkey

Xueqin Gao

Department of Orthopaedic Surgery
University of Texas Health Science Center
USA

Nils Ole Schmidt

Neurosurgeon
Department of Neurosurgery
University Medical Center Hamburg-Eppendorf
Germany
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