Articles Related to SV

Gestational diabetes mellitus (GDM) is associated with an increased maternal and fetal risk of complications. Other than lifestyle modifications and diet, little prevention can be done towards this maternal complication. Through a preclinical approach and a retrospective clinical trial, we investigated the effects of maternal supplementation with a nutraceutical composition based on resveratrol (RSV) and alpha-lipoic acid (ALA) on insulin resistance and GDM status

View complete article: PDF  |  Full-text

Respiratory Syncytial Virus is an etiological cause of lower respiratory tract infections. Due to the controversial therapeutic approach, it has a significant share in the causes of hospitalizations and even fatal outcomes concerning children up to two years of age. The elderly patients, especially the immune compromised and those with co-morbidities, are at a great risk of developing severe conditions because it is often not considered as pathogen. Those are the reasons which determine the necessity of prophylaxis of the abovementioned target groups of patients - children up to two years of age and adults over 65 years of age.

View complete article: PDF  |  Full-text

Carica papaya x vasconcelleacauliflora and intergeneric F1 hybrids of these species were screened for resistance to severely infected papaya ringspot virus isolates of papaya ringspot virus. Artificial screening for papaya ringspot virus was carried out 27 days after sap inoculation. Out of twenty-nine F1 hybrid plants of CO 7 x Vasconcelleacauliflora, only six plants were found free from PRSV symptoms. Similarly, out of fifty-five F1 hybrid plants of PusaNanha x Vasconcelleacaulifloraonly twenty-three were found free from the symptoms and seventy plants out of 335 plants of CP50 x Vasconcelleacauliflora were found free from PRSV symptoms. The resistance of the hybrids and parents and their hybrids viz, CO 7 x Vasconcelleacauliflora, PusaNanha x Vasconcelleacauliflora and CP50 x Vasconcelleacauliflora were subjected to DAS ELISA test. Molecular marker viz, ISSR markers were used to check and verify the hybridity. ISSR markers showed confirmity on three hybrid progenies viz, CO7V3, CO7V5 and CO7V6 from CO 7 xVasconcelleacauliflora.

View complete article: PDF  |  Full-text

Diabetic macular edema (DME) has become one of the most potential complications that results in loss of vision in patients with diabetic retinopathy. Treatment outcomes that have been predicted directly with advent of machine learning (ML) methods after the initial anti-vascular endothelial growth factor (anti-VEGF) injection, has become extremely vital in the management of DME. Purpose: The aim of this study is to analyze the efficiency of the ML regression models which were developed and validated to predict the possible post-injection central subfield thickness (CST) value and distant vision best corrected visual acuity (DV BCVA) in eyes with DME before the anti-VEGF injection is administered at either treatment initiation or during treatment monitoring. Methods: This retrospective study was conducted in Medical Research Foundation, Chennai, India from January 2010 to December 2020. The model development emphasized on an ensemble ML system consisting of four ML models that were developed and trained independently using the clinical parameters to predict the post injection CST value. The dataset consisting of 906 patients with total of 1874 samples [Optical coherence tomography (OCT) images and clinical parameters] were divided into trained and test set, and the model was validated on test dataset. The predicted CST values was then compared against the respective sample’s post injection actual CST value. The comparative results were measured in terms of Correlation Coefficient and Mean Absolute Relative Error (MARE). Results: On evaluation, we found that Support Vector Regression (SVR) with linear kernel performed best among the other models with four different scenarios in term of both CST and DVBCVA prediction with correlation coefficient of 0.65, 0.73, 0.75, 0.85 and 0.83, 0.87, 0.89 and 0.92 respectively.

View complete article: PDF  |  Full-text

African region is thought to contribute to >50% of deadly cases of pertussis worldwide, however surveillance and available data on Bordetella pertussis circulation are limited. Currently, pertussis vaccination schedule in most African countries is restricted to a primary immunization consisting of three doses during the first year of life using whole pertussis vaccines for which effectiveness is not known.

View complete article: PDF  |  Full-text

In contrast to previous years which consistently had an influenza “season” our clinical virology laboratory has made only a strikingly small number of identifications of influenza during the early weeks of this respiratory virus season. This experience is similar to its decreased activity in the Southern Hemisphere during their winter, April to July 2020. We report the same experience with RSV. These results are likely attributable to measures employed for control of COVID-19, including social distancing and the use of face masks.

View complete article: PDF  |  Full-text

Insulin resistance (IR) is almost constistently associated with overweight or obesity in both diabetic and non-diabetic subjects. Nutraceutical compounds improving insulin resistance (IR) may be useful in prevention and treatment of cardiovascular (CV) risk factors in metabolic diseases.

View complete article: PDF  |  Full-text

Bronchiolitis is the most common infection of the lower airways of the 1st year. Infants with severe respiratory distress (2-3%) require hospital care. The aim of the study is to evaluate the frequency of Respiratory Virus (VRS) infection, the usefulness of the diagnostic score, the ventilatory support and the protective effect of vaccinations.

View complete article: PDF  |  Full-text

In this paper, a mathematical five-dimensional dynamical system involving an SVEIR model of infectious disease transmission in a chemostat is proposed. A profound qualitative analysis is given. The analysis of the local and global stability of equilibrium points is carried out. It is proved that if R>1, then the disease-persistence (endemic) equilibrium is globally asymptotically stable. However, if 1≤R, then the disease-free equilibrium is globally asymptotically stable in R5.

View complete article: PDF  |  Full-text

Bioavailability in different formulations of desvenlafaxine100 mg prolonged-release tablets was compared in two bioequivalence studies, one under fasting conditions and the other after a standard breakfast. Both studies were a single dose, randomized, open-label, two-period crossover, with Brazilian male and female healthy subjects. Blood samples were taken during 48 h and plasmatic concentrations were determined using a validated UPLC-MS/MS method.

View complete article: PDF  |  Full-text

This paper studies the theoretic and practical solutions of appearance of reactive power and compensation of it in the 25 kV, 50 Hz supply system of the Serbian Railway. The article proposes the theoretic (by using formulas, equivalent, structural schemes, phasor diagrams) and practical research (by providing the schemes of connecting capacitor banks, calculating the parameters of capacitor banks) for the compensation of reactive power.

View complete article: PDF  |  Full-text

Globally 42 million adults and children are estimated to be living with HIV/AIDS of which 22 million of these cases are in Sub Sahara Africa. In Zimbabwe 1.6 million adults aged 15 years and above are living with HIV/ AIDS and in Masvingo Province HIV/AIDS is ranked 2nd on the top ten causes of OPD attendance.

View complete article: PDF  |  Full-text

We investigated the histopathological changes observed in the brains, organs, and apoptotic changes in the brain of young rats born from rats with torsio uteri that survive. We divided 10 Sprague-Dawley rats with a gestational age of 18-19 days into two groups. The rats in group 1 (i.e., the control group; n=5) were given anesthesia only; the rats in group 2 (study group; n=5) underwent a 360-degree clockwise torsion in their uterus, and the torsion was corrected after 6 hours. The births of the offspring were followed, and 7 female and male offspring 1 month of age were selected in each group. The vaginal openings of the young female offspring were checked to determine the time to reach puberty. The 1-month-old male offspring and the mature young female rats were then decapitated. Tissue samples, including visceral organs, genital organs, and brains, were evaluated by histapathologically; we also investigated apoptosis via the TUNEL method. Although no abortion was observed in any of the pregnant rats in the control group, two abortions were observed in the study group after torsion/detorsion.

View complete article: PDF  |  Full-text

Mesenchymal stem cells (MSCs) have been found in almost all tissues and due to their regenerative properties represent promising tools in cell-based therapy. Role of MSCs in tissue repair is strongly governed by their interplay with immune cells and regulating factors.

View complete article: PDF  |  Full-text

Inguinal hernia is a common surgical problem, but it can present a surgical dilemma for the skilled surgeon when it exhibits some unusual contents.

View complete article: PDF  |  Full-text